932-53-6

中文名称 6-氮杂胸腺嘧啶

英文名称 6-AZATHYMINE

CAS 932-53-6

EINECS 编号 213-253-9

分子式 C4H5N3O2

MDL 编号 MFCD00006457

分子量 127.1

MOL 文件 932-53-6.mol

更新日期 2025/10/22 11:23:17

932-53-6 结构式

基本信息物理化学性质安全数据上下游产品信息图谱信息知名试剂公司产品信息 6-氮杂胸腺嘧啶价格(试剂级) 常见问题列表

基本信息

中文别名

6-氮杂胸腺嘧啶
6-吖胸嘧啶
6-氮胸嘧啶

英文别名

1,2,4-TRIAZINE-3,5(2H,4H)-DIONE, 6-METHYL-
3,5-DIHYDROXY-6-METHYL-1,2,4-TRIAZINE
6-AZA-2,4-DIHYDROXY-5-METHYL-PYRIMIDINE
6-AZA-5-METHYLURACIL
6-AZATHYMINE
6-METHYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE
4h)-dione,6-methyl-as-triazine-5(2h
4-triazine-3,5(2h,4h)-dione,6-methyl-2
5-Methyl-6-azauracil
6-Methyl-1,2,4-triazine-3,5-dione
6-methyl-as-triazine-3,5-(2h,4h)-dione
6-Methyl-as-triazine-3,5(2H,4H)-dione
6-methyl-as-triazine-3,5-diol
ai3-50849
as-Triazine-3,5(2H,4H)-dione, 6-methyl-
As-triazine-3,5-diol, 6-methyl-
USAF cb-28
usafcb-28
6-Azathymine,98%
6-METHYL-S-TRIAZINE-3,5-DIONE

所属类别

生物化工：核苷酸及其类似物

物理化学性质

熔点210-212°C

沸点235.85°C (rough estimate)

密度1.4748 (rough estimate)

折射率1.5000 (estimate)

酸度系数(pKa)7.6(at 25℃)

形态粉末晶体

颜色白色到近乎白色

Merck14,903

BRN126863

InChIInChI=1S/C4H5N3O2/c1-2-3(8)5-4(9)7-6-2/h1H3,(H2,5,7,8,9)

InChIKeyXZWMZFQOHTWGQE-UHFFFAOYSA-N

SMILESN1=C(C)C(=O)NC(=O)N1

CAS 数据库932-53-6(CAS DataBase Reference)

安全数据

危险性符号(GHS) GHS hazard pictograms

GHS07

警示词警告

危险性描述H335-H319-H302-H315

防范说明P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

安全说明S22-S24/25

RTECS号XY8050000

海关编码2934.10.9000

危险等级IRRITANT

上下游产品信息

上游原料

钠醋酸钠乙二醇丙酮酸盐酸氨基脲

图谱信息

6-氮杂胸腺嘧啶(932-53-6)质谱(MS)
6-氮杂胸腺嘧啶(932-53-6)核磁图(¹HNMR)
6-氮杂胸腺嘧啶(932-53-6)核磁图(¹³CNMR)
6-氮杂胸腺嘧啶(932-53-6)红外图谱(IR1)
6-氮杂胸腺嘧啶(932-53-6)红外图谱(IR2)

知名试剂公司产品信息

Alfa Aesar

6-氮杂胸腺嘧啶,98%
6-Azathymine, 98%(932-53-6)

TCI Shanghai

6-氮杂胸腺嘧啶
6-Azathymine,>98.0%(LC)(T)(932-53-6)

6-氮杂胸腺嘧啶价格(试剂级)

报价日期	产品编号	产品名称	CAS号	包装	价格
2025/09/19	L06762	6-氮杂胸腺嘧啶, 98% 6-Azathymine, 98%	932-53-6	5g	1036元
2025/05/22	L06762	6-氮杂胸腺嘧啶, 98% 6-Azathymine, 98%	932-53-6	25g	4138元
2025/05/22	HY-136559	6-氮杂胸腺嘧啶 6-Azathymine	932-53-6	100mg	600元

常见问题列表

生物活性

6-Azathymine，胸腺嘧啶的 6-氮类似物，是一种有效的 D-3-氨基异丁酸酯-丙酮酸氨基转移酶 (D-3-aminoisobutyrate-pyruvate aminotransferase) 抑制剂。6-Azathymine 可抑制 DNA 的生物合成，并具有抗菌和抗病毒活性。

体外研究

6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis (8043) and several other strains of microorganisms. Studies of the mechanism of action of 6-Azathymine reveal that S. faecalis can convert the analog to the corresponding deoxyriboside, azathymidine.

体内研究

The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5- ¹⁴ C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives.