959-23-9
中文名称
4'-甲氧基查耳酮
英文名称
4'-METHOXYCHALCONE
CAS
959-23-9
EINECS 编号
213-495-5
分子式
C16H14O2
MDL 编号
MFCD00008407
分子量
238.28
MOL 文件
959-23-9.mol
更新日期
2023/03/20 19:41:21
959-23-9 结构式
基本信息
中文别名
4'-甲氧基查耳酮,97%1-(4-甲氧基苯基)-3-苯基丙-2-烯-1-酮
英文别名
1-(4-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE2-BENZYLIDENE-4'-METHOXYACETOPHENONE
4'-METHOXYCHALCONE
(E)-1-(4-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE
METHOXYCHALCONE, 4'-
RARECHEM AM UC 0609
alpha-styryl p-anisyl ketone
4'-METHOXYCHALCONE 97%
Benzylidene(4-methoxyacetophenone)
4'-Methoxychalcone,97%
1-(4-Methoxyphenyl)-3-phenyl-2-propen-1-one
4-Methoxyphenylstyryl ketone
Styryl(4-methoxyphenyl) ketone
β-Phenyl-4'-methoxyacrylophenone
所属类别
生物化工：提取物物理化学性质
熔点101-103 °C(lit.)
沸点397.5±42.0 °C(Predicted)
密度1.114±0.06 g/cm3(Predicted)
形态Solid
颜色White to light yellow
水溶解性Soluble in dichloromethane and methanol. Insoluble in water.
BRN644640
LogP4.180 (est)
4'-甲氧基查耳酮价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-128400 | 4'-甲氧基查耳酮 4'-Methoxychalcone | 959-23-9 | 25mg | 350元 |
| 2025/02/08 | HY-128400 | 4'-甲氧基查耳酮 4'-Methoxychalcone | 959-23-9 | 10 mM * 1 mLin DMSO | 385元 |
| 2025/02/08 | HY-128400 | 4'-甲氧基查耳酮 4'-Methoxychalcone | 959-23-9 | 50mg | 620元 |
常见问题列表
生物活性
4'-Methoxychalcone存在于柑橘属植物中，是一种查耳酮衍生物，具有多种药理活性，如抗肿瘤和消炎活性。靶点
PPARγ
体外研究
4'-Methoxychalcone (5 μM; 8 days) markedly increases the mRNA expression of adipogenic genes during adipocyte differentiation, PPARγ, aP2, FAS, adiponectin and GluT 4. 4'-Methoxychalcone (5 μM; 8 days) reduces the upregulated mRNA expression of IL-6, PAI-1, and MCP-1 by TNF-α in preadipocyte 3T3-L1 cells. 4'-Methoxychalcone (5 μM; 0-8 days) causes an increase in PPARγ expression during differentiation, while C/EBPβ protein expression is relatively unaffected.
RT-PCR
| Cell Line: | Preadipocyte 3T3-L1 cells |
| Concentration: | 5 μM |
| Incubation Time: | 0 day; 2 days; 4 days; 6 days; 8 days |
| Result: | Increased the mRNA expression of all adipogenic genes, except GluT1 in adipocyte. |
Western Blot Analysis
| Cell Line: | Preadipocyte 3T3-L1 cells |
| Concentration: | 5 μM |
| Incubation Time: | 8 days |
| Result: | Increased PPARγ expression in adipocyte. |