地贝卡星
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- CAS号:
- 34493-98-6
- 英文名:
- (2R,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
- 英文别名:
- DIBEKACIN;ibekacin;Aids070753;Brn 1441606;Aids-070753;4)]-2-deoxy-;Dibekacin USP/EP/BP;4'-Dideoxykanamycin B;Dibekacin（Dideoxykanamycin B）;D-StreptaMine,O-3-aMino-3-deoxy-a-D-glucopyranosyl-(1®
- 中文名:
- 地贝卡星
- 中文别名:
- 地贝卡星;二苯卡沙星;化合物 T23993;化合物 Dibekacin
- CBNumber:
- CB02130442
- 分子式:
- C18H37N5O8
- 分子量:
- 451.52
- MOL File:
- 34493-98-6.mol
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地贝卡星化学性质
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比旋光度:
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D20 +132° (c = 0.65)
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沸点:
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559.28°C (rough estimate)
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密度:
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1.3132 (rough estimate)
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折射率:
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1.7600 (estimate)
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酸度系数(pKa):
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13.07±0.70(Predicted)
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CAS 数据库:
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34493-98-6
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地贝卡星性质、用途与生产工艺
地贝卡星是半合成氨基糖苷类抗生素之一，一般为硫酸盐。
地贝卡星的抗菌谱与庆大霉素相似，对铜绿假单胞菌(Pseudomonas aeruginosa)、变形杆菌(Proteus spp)、大肠埃希氏菌(Escherichia coli)、肺炎克雷伯氏菌(Klebsiella pneumoniae)和金黄色葡萄球菌(Staphylococcus aureus)有较强的抗菌活性，但抗菌力不及庆大霉素，只有对铜绿假单胞菌的抗菌力比庆大霉素强，也对耳和肾有药害，适用于治疗由敏感菌所引起的败血症、呼吸道感染、腹腔感染、泌尿道感染以及皮肤软组织感染等。
地贝卡星
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34493-98-6, 地贝卡星 相关搜索:
- 抑制剂
- 4493-98-6
- 化合物 Dibekacin
- 化合物 T23993
- 二苯卡沙星
- 地贝卡星
- 34493-98-6
- DIBEKACIN
- D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-
- ibekacin
- 4'-Dideoxykanamycin B
- Dibekacin USP/EP/BP
- (2S,3R,4S,5S,6R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,6S)-3-amino-6-(aminomethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol
- Dibekacin（Dideoxykanamycin B）
- (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
- D-StreptaMine,O-3-aMino-3-deoxy-a-D-glucopyranosyl-(1®
- 6)-O-[2,6-diaMino-2,3,4,6-tetradeoxy-a-D-erythro-hexopyranosyl-(1®
- 4)]-2-deoxy-
- O-3-AMino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diaMino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-D-streptaMine
- D-Streptamine, o-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)-(1-4)-2-deoxy-
- Brn 1441606
- Aids-070753
- Aids070753
- 6-O-(3-Amino-3-deoxy-α-D-glucopyranosyl)-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-2-deoxy-D-streptamine
- (2R,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol