1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺
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- CAS号:
- 374922-43-7
- 英文名:
- CAY10602
- 英文别名:
- CAY10602;CAY10602 HCl;CAY10602, >98%;SIRT1 Activator II;CAY10602, 10 mM in DMSO;CAY10602, SIRT1 Activator;SIRT1 Activator II - CAS 374922-43-7 - Calbiochem;Inhibitor,CAY 10602,CAY10602,CAY-10602,inhibit,Sirtuin;1-(4-Fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine;1H-Pyrrolo[2,3-b]quinoxalin-2-amine, 1-(4-fluorophenyl)-3-(phenylsulfonyl)-
- 中文名:
- 1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺
- 中文别名:
- 化合物CAY10602;CAY10602,SIRT1活化剂;化合物CAY10602,10 MM DMSO 溶液;1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺
- CBNumber:
- CB12590438
- 分子式:
- C22H15FN4O2S
- 分子量:
- 418.44
- MOL File:
- 374922-43-7.mol
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1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺化学性质
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熔点:
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270 °C
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储存条件:
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+2C to +8C
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溶解度:
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DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
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形态:
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Off-white powder
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颜色:
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Light yellow to Amber to Dark green
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CAS 数据库:
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374922-43-7
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1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺性质、用途与生产工艺
CAY10602 是一种 SIRT1 的激活剂。CAY10602 剂量依赖性地抑制 THP-1 细胞中脂多糖对 NF-κB 的 TNF-α 依赖性诱导。
Compounds (including CAY10602/compound 1) with SIRT1-activating properties have a significant effect on fat mobilization in differentiated adipocytes, and these compounds (including CAY10602) have antiobesity and/or antidiabetic properties. Compounds (including CAY10602) with SIRT1 activating potential exert strong suppression of TNF-α release at concentrations between 20 and 60 μM.
1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/02/08 | HY-104073 | 1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺
CAY10602 | 374922-43-7 | 5mg | 450元 |
| 2025/02/08 | HY-104073 | 1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺
CAY10602 | 374922-43-7 | 10mM * 1mLin DMSO | 500元 |
1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺
生产厂家
374922-43-7, 1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺 相关搜索:
- 抑制剂
- 高端化学
- 化合物CAY10602,10 MM DMSO 溶液
- CAY10602,SIRT1活化剂
- 化合物CAY10602
- 1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-B]喹喔啉-2-胺
- 374922-43-7
- SIRT1 Activator II
- CAY10602, 10 mM in DMSO
- 1-(4-Fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine/CAY10602
- CAY10602, SIRT1 Activator
- Inhibitor,CAY 10602,CAY10602,CAY-10602,inhibit,Sirtuin
- CAY10602 HCl
- 1H-Pyrrolo[2,3-b]quinoxalin-2-amine, 1-(4-fluorophenyl)-3-(phenylsulfonyl)-
- CAY10602, >98%
- SIRT1 Activator II - CAS 374922-43-7 - Calbiochem
- 1-(4-Fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
- CAY10602