GNE140 racemate
|
|
|
- CAS号:
- 1802977-61-2
- 英文名:
- GNE-140 (racemate)
- 英文别名:
- GNE-140 (racemate);GNE-140 racemate
(GNE 140 racemate;3-((2-chlorophenyl)thio)-6-(4-morpholinophenyl)-6-(thiophen-3-yl)piperidine-2,4-dione;2,4-Piperidinedione, 3-[(2-chlorophenyl)thio]-6-[4-(4-morpholinyl)phenyl]-6-(3-thienyl)-
- 中文名:
- GNE140 racemate
- 中文别名:
- 化合物 T13450L;化合物 GNE-140 RACEMATE;LDHA抑制剂(GNE-140 RACEMATE);3-((2-氯苯基)硫代)-6-(4-吗啉代苯基)-6-(噻吩-3-基)哌啶-2,4-二酮
- CBNumber:
- CB33152079
- 分子式:
- C25H23ClN2O3S2
- 分子量:
- 499.04
- MOL File:
- 1802977-61-2.mol
|
|
|
GNE140 racemate化学性质
-
沸点:
-
739.0±60.0 °C(Predicted)
-
|
-
密度:
-
1.43±0.1 g/cm3(Predicted)
-
|
-
储存条件:
-
2-8°C
-
|
-
溶解度:
-
DMSO : ≥ 34 mg/mL (68.13 mM)
-
|
-
形态:
-
Solid
-
|
-
酸度系数(pKa):
-
9.61±0.70(Predicted)
-
|
-
颜色:
-
White to off-white
-
|
GNE140 racemate性质、用途与生产工艺
GNE-140 racemate 是一种 (R)-GNE-140 和 (S)-GNE-140 的外消旋混合物。GNE-140 racemate 也是一种有效的乳酸脱氢酶 A (LDHA) 抑制剂。
Lactate dehydrogenase A (LDHA)
Increased glucose consumption distinguishes cancer cells from normal cells and is known as the “Warburg effect” because of increased glycolysis. Lactate dehydrogenase A (LDHA) is a key glycolytic enzyme, a hallmark of aggressive cancers, and believed to be the major enzyme responsible for pyruvate-to-lactate conversion.
GNE140 racemate
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/02/08 | HY-100742 | 1802977-61-2
GNE-140 racemate | 1802977-61-2 | 1mg | 1150元 |
| 2025/02/08 | HY-100742 | 1802977-61-2
GNE-140 racemate | 1802977-61-2 | 5mg | 2850元 |
1802977-61-2, GNE140 racemate 相关搜索:
- 抑制剂
- 细胞生物学试剂
- 化合物 GNE-140 RACEMATE
- 化合物 T13450L
- 3-((2-氯苯基)硫代)-6-(4-吗啉代苯基)-6-(噻吩-3-基)哌啶-2,4-二酮
- LDHA抑制剂(GNE-140 RACEMATE)
- 1802977-61-2
- 2,4-Piperidinedione, 3-[(2-chlorophenyl)thio]-6-[4-(4-morpholinyl)phenyl]-6-(3-thienyl)-
- 3-((2-chlorophenyl)thio)-6-(4-morpholinophenyl)-6-(thiophen-3-yl)piperidine-2,4-dione
- GNE-140 (racemate)
- GNE-140 racemate
(GNE 140 racemate