16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮
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- CAS号:
- 1922-48-1
- 英文名:
- 16beta-Methyl-16alpha,17alpha-epoxypregnenolone
- 英文别名:
- Ambiguanol;16,17-Epoxy-16-methylpregnenolone;16|-Methyl-16|,17|-epoxypregnenolone;16b-methyl-16a,17a-epoxypregnenolone;16,17-Epoxy-6-methylpregn-5-en-3-ol-20-one;5-PREGNEN-16, 17-EPOXY-16β-METHYL-3β-OL-20-ONE;16BETA-METHYL-16ALPHA,17ALPHA-EPOXYPREGNENOLONE;5-Pregnen-16α,17α-epoxy-16β-methyl-3β-ol-20-one;16,17-Epoxy-3-hydroxy-16-methyl-pregn-5-en-20-one;3β-Hydroxy-16β-methyl-16α,17α-oxido-Δ5-pregnenon-20
- 中文名:
- 16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮
- 中文别名:
- 美伦孕酮中间体;化合物T3223;化合物 AMBIGUANOL;16α,17α-环氧-16β-甲基孕甾-5-烯-3β-醇-20-酮;16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮;16ALPHA,17ALPHA-环氧-3Β-羟基-16Β-甲基孕甾-5-烯-20-酮;化合物16BETA-METHYL-16ALPHA,17ALPHA-EPOXYPREGNENOLONE
- CBNumber:
- CB4155931
- 分子式:
- C22H32O3
- 分子量:
- 344.49
- MOL File:
- 1922-48-1.mol
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16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮化学性质
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熔点:
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189-191 °C(Solv: acetone (67-64-1); hexane (110-54-3))
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沸点:
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462.3±45.0 °C(Predicted)
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密度:
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1.17±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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14.99±0.70(Predicted)
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16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮性质、用途与生产工艺
化学性质
结晶化合物，熔点为165-185℃。
用途
地塞米松醋酸酯的中间体。
生产方法
可用3β-羟基孕甾-5,16-二烯-20-酮-3-醋酸酯（即妊娠双烯醇酮醋酸酯）经（与亚硝基甲基脲）加成并消除，生成3β-羟基-16β-甲基孕甾-5,16-二烯-20-酮-3-醋酸酯，然后与过氧化氢反应，环氧化后制得该品。
16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮
上下游产品信息
上游原料
下游产品
16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮
生产厂家
1922-48-1, 16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮 相关搜索:
- 抑制剂
- 有机中间体
- C22H32O3
- 化合物 AMBIGUANOL
- 美伦孕酮中间体
- 化合物T3223
- 化合物16BETA-METHYL-16ALPHA,17ALPHA-EPOXYPREGNENOLONE
- 16ALPHA,17ALPHA-环氧-3Β-羟基-16Β-甲基孕甾-5-烯-20-酮
- 16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮
- 16α,17α-环氧-16β-甲基孕甾-5-烯-3β-醇-20-酮
- 1922-48-1
- 16,17-Epoxy-16-methylpregnenolone
- 5-PREGNEN-16, 17-EPOXY-16β-METHYL-3β-OL-20-ONE
- Pregn-5-en-20-one, 16,17-epoxy-3-hydroxy-16-methyl-, (3β,16α)-
- 16beta Methyl 16alpha,17alpha epoxypregnenolone,16betaMethyl16alpha,17alphaepoxypregnenolone
- Pregn-5-en-20-one,16,17-epoxy-3-hydroxy-16-methyl-, (3b,16a)-
- Ambiguanol
- 5-Pregnen-16α,17α-epoxy-16β-methyl-3β-ol-20-one
- 3β-Hydroxy-16β-methyl-16α,17α-epoxy-5-pregnen-20-one
- (17R)-16β,17-Epoxy-3β-hydroxy-16-methylpregn-5-en-20-one
- 16|-Methyl-16|,17|-epoxypregnenolone
- 5-Pregnen-16α,17α-epoxy-16β-methyl-3β-ol-20-one, 3β-Hydroxy-16β-methyl-16α,17α-epoxy-5-pregnen-20-one
- 3β-Hydroxy-16β-methyl-16α,17α-oxido-Δ5-pregnenon-20
- 16-alpha,17-alpha-epoxy-3-beta-hydroxy-16-beta-methylpregn-5-en-20-one
- 16BETA-METHYL-16ALPHA,17ALPHA-EPOXYPREGNENOLONE
- 16b-methyl-16a,17a-epoxypregnenolone
- 16,17-Epoxy-3-hydroxy-16-methyl-pregn-5-en-20-one
- 16,17-Epoxy-6-methylpregn-5-en-3-ol-20-one
- 5-PREGNEN-16ALPHA,17ALPHA-EPOXY-16BETA-METHYL-3BETA-OL-20-ONE
- 3BETA-HYDROXY-16BETA-METHYL-16ALPHA,17ALPHA-EPOXY-5-PREGNEN-20-ONE