普拉洛尔
|
|
|
- CAS号:
- 6673-35-4
- 英文名:
- Practolol
- 英文别名:
- dalzic;ay21011;eraldin;ici50172;PRACTOLOL;practalol;praktololu;dl-Practolol;rac Practolol;RaceMic Practolol
- 中文名:
- 普拉洛尔
- 中文别名:
- 心得宁;醋心安;醋氨心安;普拉洛尔;N-(4-(2-羟基-3-(异丙基氨基)丙氧基)苯基)乙酰胺;N-[4-[2-羟基-3-[(1-甲基乙基)氨基]丙氧基]苯基]乙酰胺
- CBNumber:
- CB4295109
- 分子式:
- C14H22N2O3
- 分子量:
- 266.34
- MOL File:
- 6673-35-4.mol
|
|
|
普拉洛尔化学性质
-
熔点:
-
134-136° (BuOAc)
-
|
-
沸点:
-
409.54°C (rough estimate)
-
|
-
密度:
-
1.0807 (rough estimate)
-
|
-
折射率:
-
1.5110 (estimate)
-
|
-
储存条件:
-
Refrigerator
-
|
-
溶解度:
-
DMSO (Slightly), Methanol (Slightly)
-
|
-
形态:
-
Solid
-
|
-
酸度系数(pKa):
-
pKa 9.5 (Uncertain)
-
|
-
颜色:
-
White to Off-White
-
|
普拉洛尔性质、用途与生产工艺
Practolol 是一种有效和选择性的 β1 肾上腺素能受体拮抗剂。Practolol 可用于心律失常的研究。
Practolol (10 μM; 30 min) preferentially antagonizes the relaxant effects produced by R0363 in spontaneously contracted tracheal preparations from the guinea-pig.
Practolol (10 nM-100 μM) blocks the progesterone production induced by (-)epinephrine in a dose-dependent manner in granulosa cells.
Practolol (0.5 mg/kg; i.v.) decreases heart rate, left ventricular
dP/dt max
, myocardial blood flow and cardiac output in intact close-chest dogs.
Practolol (0.5 mg/kg; i.v.) decreases normal myocardial blood flow but flow in the ischaemic area remains unchanged after coronary artery ligation.
用途
心血管系统用药。
普拉洛尔
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/02/08 | HY-119802 | 普拉洛尔
Practolol | 6673-35-4 | 1 mg | 172元 |
| 2025/02/08 | HY-119802 | 普拉洛尔
Practolol | 6673-35-4 | 5 mg | 430元 |
普拉洛尔
生产厂家
全球有 50家供应商
普拉洛尔国内生产厂家
6673-35-4, 普拉洛尔 相关搜索:
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Inhibitors
- Aromatics
- FDA批准的配体
- N-(4-(2-羟基-3-(异丙基氨基)丙氧基)苯基)乙酰胺
- N-[4-[2-羟基-3-[(1-甲基乙基)氨基]丙氧基]苯基]乙酰胺
- 心得宁
- 醋心安
- 醋氨心安
- 普拉洛尔
- 6673-35-4
- N-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide , Practolol
- receptor,inhibit,arrhythmias,β1-adrenergic,Practolol,Beta Receptor,Adrenergic Receptor,cardiac,Inhibitor
- N-[4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETAMIDE USP/EP/BP
- Acetamide, N-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-
- eraldin
- dalzic
- ay21011
- 4’-(2-hydroxy-3-(isopropylamino)propoxy)acetanilide
- 4’-(2-hydroxy-3-(isopropylamino)propoxy)-acetanilid
- 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol
- N-[4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETAMIDE
- PRACTOLOL
- N-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
- praktololu
- practalol
- n-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-acetamid
- ici50172
- RaceMic Practolol
- rac Practolol
- dl-Practolol
- DL-4'-[2-Hydroxy-3-(isopropylaMino)propoxy]acetanilide