DBCO-PEG4-DBCO
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- CAS号:
- 2182601-68-7
- 英文名:
- DBCO-PEG4-DBCO
- 英文别名:
- DBCO-PEG4-DBCO;Bis-DBCO-NHCO-PEG4;DBCO-NHCO-PEG4-CONH-DBCO;4,7,10,13-Tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-
- 中文名:
- DBCO-PEG4-DBCO
- 中文别名:
- DBCO-四聚乙二醇-DBCO;二苯并环辛炔-PEG4-二苯并环辛炔;化合物 DBCO-PEG4-DBCO;二苯并环辛炔-四聚乙二醇-二苯并环辛炔;N1,N16-双[3-(11,12-二脱氢二苯并[B,F]氮杂环辛炔-5(6H)-基)-3-氧代丙基]-4,7,10,13-四氧杂十六烷二酰胺
- CBNumber:
- CB43339239
- 分子式:
- C48H50N4O8
- 分子量:
- 810.93
- MOL File:
- 2182601-68-7.mol
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DBCO-PEG4-DBCO化学性质
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沸点:
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1104.6±65.0 °C(Predicted)
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密度:
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1.30±0.1 g/cm3(Predicted)
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储存条件:
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-20°C, sealed storage, away from moisture
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形态:
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Solid
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酸度系数(pKa):
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14.84±0.46(Predicted)
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颜色:
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White to yellow
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DBCO-PEG4-DBCO性质、用途与生产工艺
DBCO-PEG4-DBCO 是一种 PROTAC 连接桥，属于 PEG 类。DBCO-PEG4-DBCO 可用于合成一系列 PROTAC 分子。DBCO-PEG4-DBCO 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
DBCO-PEG4-DBCO
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/05/22 | HY-130346 | DBCO-PEG4-DBCO | 2182601-68-7 | 25 mg | 1157元 |
| 2025/05/22 | HY-130346 | DBCO-PEG4-DBCO
DBCO-PEG4-DBCO | 2182601-68-7 | 50 mg | 2040元 |
2182601-68-7, DBCO-PEG4-DBCO 相关搜索:
- 抑制剂
- 助剂
- C48H50N4O8
- 化合物 DBCO-PEG4-DBCO
- N1,N16-双[3-(11,12-二脱氢二苯并[B,F]氮杂环辛炔-5(6H)-基)-3-氧代丙基]-4,7,10,13-四氧杂十六烷二酰胺
- 二苯并环辛炔-PEG4-二苯并环辛炔
- DBCO-四聚乙二醇-DBCO
- 二苯并环辛炔-四聚乙二醇-二苯并环辛炔
- 2182601-68-7
- DBCO-NHCO-PEG4-CONH-DBCO
- 4,7,10,13-Tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-
- Bis-DBCO-NHCO-PEG4
- DBCO-PEG4-DBCO