DBCO-PEG4-DBCO
- CAS No.
- 2182601-68-7
- Chemical Name:
- DBCO-PEG4-DBCO
- Synonyms
- DBCO-PEG4-DBCO;Bis-DBCO-NHCO-PEG4;DBCO-NHCO-PEG4-CONH-DBCO;4,7,10,13-Tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-
- CBNumber:
- CB43339239
- Molecular Formula:
- C48H50N4O8
- Molecular Weight:
- 810.93
- MDL Number:
- MFCD31536768
- MOL File:
- 2182601-68-7.mol
DBCO-PEG4-DBCO Chemical Properties,Uses,Production
Description
DBCO-PEG4-DBCO is a homobifunctional PEG linker containing two DBCO groups and a hydrophilic PEG spacer arm. DBCO will react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. The hydrophilic PEG spacer arm can increase water solubility and membrane permability.
Uses
DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
Cleavable Linker; PEGs
References
[1] Adam TIBBLES, et al. Engineered O-glycosylation in recombinant polypeptides via heterologous glycosylation sites. WO2019122234A1.
DBCO-PEG4-DBCO Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG4-DBCO Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32433 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Shanghai 9i Technology Co., Ltd. | 021-33555271 18201009191 | MWen@9iLab.com | China | 133 | 58 |
View Lastest Price from DBCO-PEG4-DBCO manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-22 | DBCO-PEG4-DBCO
2182601-68-7
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | DBCO-PEG4-DBCO
2182601-68-7
|
US $0.00 / mg | 25mg | >99.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- DBCO-PEG4-DBCO
2182601-68-7
- US $0.00 / mg
- TargetMol Chemicals Inc.
-
- DBCO-PEG4-DBCO
2182601-68-7
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
