DBCO-PEG4-DBCO
- CAS No.
- 2182601-68-7
- Chemical Name:
- DBCO-PEG4-DBCO
- Synonyms
- DBCO-PEG4-DBCO;Bis-DBCO-NHCO-PEG4;DBCO-NHCO-PEG4-CONH-DBCO;4,7,10,13-Tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-
- CBNumber:
- CB43339239
- Molecular Formula:
- C48H50N4O8
- Molecular Weight:
- 810.93
- MDL Number:
- MFCD31536768
- MOL File:
- 2182601-68-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
DBCO-PEG4-DBCO price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0107400 | DBCO-PEG4-DBCO ≥97% | 2182601-68-7 | 25mg | $132 | 2026-06-04 | Buy |
| ChemScene | CS-0107400 | DBCO-PEG4-DBCO ≥97% | 2182601-68-7 | 50mg | $263 | 2026-06-04 | Buy |
| ChemScene | CS-0107400 | DBCO-PEG4-DBCO ≥97% | 2182601-68-7 | 100mg | $538 | 2026-06-04 | Buy |
| BroadPharm | bp-23772 | DBCO-PEG4-DBCO 98% | 2182601-68-7 | 25MG | $180 | 2026-05-24 | Buy |
| BroadPharm | bp-23772 | DBCO-PEG4-DBCO 98% | 2182601-68-7 | 50MG | $290 | 2026-05-24 | Buy |
DBCO-PEG4-DBCO Chemical Properties, Uses, Production
Description
DBCO-PEG4-DBCO is a homobifunctional PEG linker containing two DBCO groups and a hydrophilic PEG spacer arm. DBCO will react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. The hydrophilic PEG spacer arm can increase water solubility and membrane permability.
Uses
DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
Cleavable Linker; PEGs
References
[1] Adam TIBBLES, et al. Engineered O-glycosylation in recombinant polypeptides via heterologous glycosylation sites. WO2019122234A1.
DBCO-PEG4-DBCO Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG4-DBCO Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai 9i Technology Co., Ltd. | 021-33555271 18201009191 | MWen@9iLab.com | China | 133 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3147 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1927 | 58 |
| Henan Lien Chemical Products Co., Ltd. | 0371-63357898 15378766539 | 535046669@qq.com | China | 5821 | 58 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Zhengzhou Convergence Chemical Co. LTD | 13393710386 | 3941078109@qq.com | China | 9905 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9932 | 58 |
View Latest Price from DBCO-PEG4-DBCO manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-22 | DBCO-PEG4-DBCO
2182601-68-7
|
10g | TargetMol Chemicals Inc. | ||||
 |
2025-06-07 | DBCO-PEG4-DBCO
2182601-68-7
|
25mg | >99.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- DBCO-PEG4-DBCO
2182601-68-7
- $0.00
- TargetMol Chemicals Inc.
-
- DBCO-PEG4-DBCO
2182601-68-7
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
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