硫酸奥西那林
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- CAS号:
- 5874-97-5
- 英文名:
- Orciprenaline sulfate
- 英文别名:
- METAPROTERENOL SULFATE;alupent;alotec;th-152;metaprel;Astmopent;novasmasol;ORCIPRENALINE SULFATE;dl-Orciprenaline sulfate;METAPROTERENOLSULFATE,USP
- 中文名:
- 硫酸奥西那林
- 中文别名:
- 硫酸异丙喘宁;硫酸奥西那林;硫酸奥昔帕林;异丙喘宁硫酸盐;奥西那林硫酸盐;硫酸奥肾上腺素;奥西那林半硫酸盐;硫酸奥西那林杂质;硫酸奥西那林-D6;硫酸奥西那林 标准品
- CBNumber:
- CB7226328
- 分子式:
- C22H36N2O10S
- 分子量:
- 520.59
- MOL File:
- 5874-97-5.mol
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硫酸奥西那林化学性质
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熔点:
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202-203°
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储存条件:
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2-8°C
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溶解度:
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Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
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形态:
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Solid
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颜色:
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White to Off-White
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稳定性:
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Hygroscopic
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硫酸奥西那林性质、用途与生产工艺
Metaproterenol hemisulfate (Orciprenaline hemisulfate) 是一种直接作用的拟交感神经药，是 β2-肾上腺素能受体 (β2AR) 激动剂，其 IC50 为 68 nM。Metaproterenol hemisulfate 还具有抗炎活性。
IC50: 68 nM (β2-adrenergic receptor)
Metaproterenol (10 μM; 74 hours; THP-1 cells and bone marrow macrophages) treatment enhances β-arrestin2 and its interaction with IκBα in high glucose-induced THP-1 cells and bone marrow macrophages.
Metaproterenol (10 μM; 74 hours; THP-1 cells and bone marrow macrophages) treatment leads to downregulation of NF-κB in high glucose-induced THP-1 cells and bone marrow macrophages.
Western Blot Analysis
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Cell Line:
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THP-1 cells and bone marrow macrophages
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Concentration:
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10 μM
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Incubation Time:
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74 hours
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Result:
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Enhanced β-arrestin2 and its interaction with IκBα.
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RT-PCR
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Cell Line:
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THP-1 cells and bone marrow macrophages
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Concentration:
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10 μM
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Incubation Time:
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74 hours
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Result:
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Led to downregulation of NF-κB.
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Treatment of Zucker diabetic fatty rats with Metaproterenol for 12 weeks attenuates monocyte activation as well as pro-inflammatory and pro-fibrotic responses in the kidneys and heart. Thus, Metaproterenol might has protective effects against diabetic renal and cardiovascular complications.
硫酸奥西那林
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/05/22 | HY-B1276 | 硫酸奥西那林
Metaproterenol hemisulfate | 5874-97-5 | 5 mg | 171元 |
| 2025/05/22 | HY-B1276 | 硫酸奥西那林
Metaproterenol hemisulfate | 5874-97-5 | 10mM * 1mLin DMSO | 188元 |
硫酸奥西那林
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硫酸奥西那林国内生产厂家
5874-97-5, 硫酸奥西那林 相关搜索:
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- 医药原料药
- beta2-adrenoceptor agonist
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- 间丙肾上腺素半硫酸盐
- 硫酸奥西那林杂质
- 硫酸奥西那林-D6
- 奥西那林半硫酸盐 异丙喘宁
- 硫酸奥肾上腺素
- 硫酸奥昔帕林
- 奥西那林硫酸盐 EP标准品
- 硫酸奥西那林ORCIPRENALINE SULFATE
- 硫酸奥西那林 标准品
- 奥西那林硫酸盐
- 硫酸奥西那林 USP标准品
- 奥西那林系统适用性 EP标准品
- 硫酸异丙喘宁
- 奥西那林半硫酸盐
- 奥西那林半硫酸盐 标准品
- 异丙喘宁硫酸盐
- 硫酸奥西那林(异丙喘宁)
- 异丙喘宁硫酸盐溶液,100PPM
- 硫酸奥西那林
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- 5874-97-5
- Metaproterenol hemisulfate, 10 mM in DMSO
- 1,3-Benzenediol, 5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, sulfate (2:1)
- Inhibitor,Beta Receptor,Metaproterenol hemisulfate,inhibit,Orciprenaline hemisulfate,Adrenergic Receptor
- Metaproterenol Sulfate (1395500)
- Orciprenaline sulphateQ: What is
Orciprenaline sulphate Q: What is the CAS Number of
Orciprenaline sulphate Q: What is the storage condition of
Orciprenaline sulphate Q: What are the applications of
Orciprenaline sulphate
- Orciprenaline sulfate USP/EP/BP
- 5-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,3-diol hemisulfate
- Orciprenaline for system suitability CRS
- Orciprenaline sulfate CRS
- Orciprenaline hemisulfate Solution, 100ppm
- Orciprenaline heMisulfate
- 5-[1-Hydroxy-2-[(1-Methylethyl)aMino]ethyl]-1,3-benzenediol Sulfate