GSK 3359088
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- CAS号:
- 1628830-21-6
- 英文名:
- GSK3359088
- 英文别名:
- CS-2741;EZM2302;GSK3359088;EZM2302 (GSK3359088);EZM 2302, 10 mM in DMSO;EZM2302;EZM-2302;EZM 2302;inhibit,Inhibitor,EZM2302,Histone Methyltransferase,EZM 2302,EZM-2302;Methyl 2-(2-(2-chloro-5-((R)-2-hydroxy-3-(methylamino)propoxy)phenyl)-6-(3,5-dimethylisoxazol-4-yl)-5-methylpyrimidin-4-yl)-2,7-diazaspiro[3.5]nonane-7-carboxylate;Methyl 2-[2-[2-chloro-5-[(2R)-2-hydroxy-3-(methylamino)propoxy]phenyl]-6-(3,5-dimethyl-4-isoxazolyl)-5-methyl-4-pyrimidinyl]-2,7-diazaspiro[3.5]nonane-7-carboxylate;methyl 2-(2-{2-chloro-5-[(2R)-2-hydroxy-3-(methylamino)propoxy]phenyl}-6-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methylpyrimidin-4-yl)-2,7-diazaspiro[3.5]nonane-7-carboxylate
- 中文名:
- GSK 3359088
- 中文别名:
- 化合物EZM 2302;化合物EZM 2302,10 MM DMSO 溶液;EZM 2302 (GSK 3359088;GSK3359088;EZM2302);2-(2-(2-氯-5-((R)-2-羟基-3-(甲基氨基)丙氧基)苯基)-6-(3,5-二甲基吡啶-4-基)-5-甲基嘧啶哌啶-4-基)-2,7-二氮杂螺[3.5]壬烷-7-羧酸乙酯
- CBNumber:
- CB93364258
- 分子式:
- C29H37ClN6O5
- 分子量:
- 585.09
- MOL File:
- 1628830-21-6.mol
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GSK 3359088化学性质
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沸点:
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705.8±60.0 °C(Predicted)
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密度:
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1.36±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO:91.0(Max Conc. mg/mL);155.53(Max Conc. mM)
DMSO:91.0(Max Conc. mg/mL);155.53(Max Conc. mM)-
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酸度系数(pKa):
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13.79±0.20(Predicted)
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形态:
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A solid
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颜色:
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White to off-white
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InChIKey:
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OWCOTUVKROVONT-HXUWFJFHSA-N
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SMILES:
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C1C2(CCN(C(OC)=O)CC2)CN1C1C(C)=C(C2=C(C)ON=C2C)N=C(C2=CC(OC[C@H](O)CNC)=CC=C2Cl)N=1
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GSK 3359088性质、用途与生产工艺
EZM 2302是共激活因子相关的精氨酸甲基转移酶1 (CARM1) 制剂， IC50值为6 nM。
GSK 3359088
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2025/05/22 | HY-111109 | EZM 2302 | 1628830-21-6 | 1 mg | 740元 |
| 2025/05/22 | HY-111109 | GSK 3359088
EZM 2302 | 1628830-21-6 | 5mg | 1625元 |
1628830-21-6, GSK 3359088 相关搜索:
- 抑制剂
- 化工原料
- C29H37ClN6O5
- EZM 2302 (GSK 3359088;GSK3359088;EZM2302)
- 化合物EZM 2302,10 MM DMSO 溶液
- 化合物EZM 2302
- 2-(2-(2-氯-5-((R)-2-羟基-3-(甲基氨基)丙氧基)苯基)-6-(3,5-二甲基吡啶-4-基)-5-甲基嘧啶哌啶-4-基)-2,7-二氮杂螺[3.5]壬烷-7-羧酸乙酯
- 1628830-21-6
- EZM 2302, 10 mM in DMSO
- methyl 2-(2-{2-chloro-5-[(2R)-2-hydroxy-3-(methylamino)propoxy]phenyl}-6-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methylpyrimidin-4-yl)-2,7-diazaspiro[3.5]nonane-7-carboxylate
- inhibit,Inhibitor,EZM2302,Histone Methyltransferase,EZM 2302,EZM-2302
- Methyl 2-[2-[2-chloro-5-[(2R)-2-hydroxy-3-(methylamino)propoxy]phenyl]-6-(3,5-dimethyl-4-isoxazolyl)-5-methyl-4-pyrimidinyl]-2,7-diazaspiro[3.5]nonane-7-carboxylate
- Methyl 2-(2-(2-chloro-5-((R)-2-hydroxy-3-(methylamino)propoxy)phenyl)-6-(3,5-dimethylisoxazol-4-yl)-5-methylpyrimidin-4-yl)-2,7-diazaspiro[3.5]nonane-7-carboxylate
- 2,7-Diazaspiro[3.5]nonane-7-carboxylic acid, 2-[2-[2-chloro-5-[(2R)-2-hydroxy-3-(methylamino)propoxy]phenyl]-6-(3,5-dimethyl-4-isoxazolyl)-5-methyl-4-pyrimidinyl]-, methyl ester
- CS-2741
- EZM2302;EZM-2302;EZM 2302
- EZM2302 (GSK3359088)
- EZM2302
- GSK3359088