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Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Struktur
184177-81-9
CAS-Nr.
184177-81-9
Englisch Name:
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Synonyma:
Posaconazole SM2;Posaconazole Impurity 14;Posaconazole Impurity 56;Intermediate of Posaconazole;piperazin-1-yl)phenylcarbamate;Phenyl (4-(4-(4-hydroxyphenyl);Posaconazole Hydroxy Carbamate Impurity;Posaconazole Diastereoisomer 3 (S,R,R,R);4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE;PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
CBNumber:
CB11476162
Summenformel:
C23H23N3O3
Molgewicht:
389.45
MOL-Datei:
184177-81-9.mol
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Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Eigenschaften

Siedepunkt:
603.9±55.0 °C(Predicted)
Dichte
1.296
storage temp. 
Sealed in dry,Room Temperature
pka
12.18±0.30(Predicted)
Aussehen
Off-white to gray Solid
InChI
InChI=1S/C23H23N3O3/c27-21-12-10-20(11-13-21)26-16-14-25(15-17-26)19-8-6-18(7-9-19)24-23(28)29-22-4-2-1-3-5-22/h1-13,27H,14-17H2,(H,24,28)
InChIKey
IKRKMYDCUZYKHX-UHFFFAOYSA-N
SMILES
C(OC1=CC=CC=C1)(=O)NC1=CC=C(N2CCN(C3=CC=C(O)C=C3)CC2)C=C1
CAS Datenbank
184177-81-9
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H410 Sehr giftig für Wasserorganismen mit langfristiger Wirkung. Langfristig (chronisch) gewässergefährdend Kategorie 1 Warnung GHS hazard pictogramssrc="/GHS09.jpg" width="20" height="20" /> P273, P391, P501
Sicherheit
P273 Freisetzung in die Umwelt vermeiden.
P391 Verschüttete Mengen aufnehmen.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a piperazine derivative that inhibits the growth of gram-positive bacteria.Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)) carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Human activity on human erythrocytes using the membrane clamp technique is frequent. This active form is metabolised by a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or binding to glucuronic acid.

Verwenden

PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE is a carboxylic acid ester organic substance and can be used as a pharmaceutical intermediate.

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Phenylchlorformiat

Downstream Produkte

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 206)Lieferanten
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184177-81-9()Verwandte Suche:

4-Methoxyphenol 1-(4-Methoxyphenyl)piperazin Toluol-4-sulfonohydrazid
  • CarbaMic acid, [4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester (9CI)
  • Posaconazole Impurity 14
  • PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
  • [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester
  • Posaconazole Diastereoisomer 3 (S,R,R,R)
  • Phenyl (4-(4-(4-hydroxyphenyl)
  • phenyl N-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]carbamate
  • 4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE
  • piperazin-1-yl)phenylcarbamate
  • Posaconazole Impurity 56
  • Posaconazole Hydroxy Carbamate Impurity
  • Carbamic acid, N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester
  • Posaconazole SM2
  • Phenyl {4-[4-(4-Hydroxyphenyl)Piperazin-1-Yl]Phenyl}Carbamat...
  • Intermediate of Posaconazole
  • Phenyl {4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl}carbamate
  • [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamicacidphenylester(SCR-4387)
  • [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester phenyl (4-(4-(4-hydroxyphenyl) piperazin-1-yl) phenyl)carbamate
  • [4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]Phenyl carbamate
  • 184177-81-9
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