ChemicalBook > Produktkatalog >Aktive pharmazeutische Wirkstoffe (APIs) >Spezialarzneimittel >Zahnärztliche Arzneimittel >Cevimeline

Cevimeline

107233-08-9

CAS-Nr.: 107233-08-9

Englisch Name:: Cevimeline

Synonyma:: Evoxac;AF-102B;SNI-2011;3R)-rel-;Hsdb 7286;Cevimeline;3]oxathiolane];AF-102B;FKS-508;CevimelineHClSalt;CeviMeline(Evoxac)

CBNumber:: CB1490161

Summenformel:: C10H17NOS

Molgewicht:: 199.31

MOL-Datei:: 107233-08-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 99

Cevimeline Eigenschaften

Schmelzpunkt:: 195-197°C

Siedepunkt:: 308.5±42.0 °C(Predicted)

Dichte: 1.19

storage temp.: Sealed in dry,Store in freezer, under -20°C

Löslichkeit: Soluble in DMSO

Aggregatzustand: Powder

pka: 9.51±0.40(Predicted)

CAS Datenbank: 107233-08-9

Sicherheit

Giftige Stoffe Daten	107233-08-9(Hazardous Substances Data)

Cevimeline Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Off-White Solid

Verwenden

A muscarinic M1 and M3 receptor agonist. Sialagogue

Synthese

The synthesis of cevimeline commences with the epoxidation of the starting material 3-quinuclidinone (2) to yield the intermediate epoxide of 3-methylenequinuclidine (3). This reacts with thiol carboxylic acid RCOSH to form compound (4), which is subsequently converted to the intermediate 3-hydroxy-3-mercaptomethylquinuclidine (5) in the presence of acid or base. and finally purified via a one-pot process.
synthesis of CEVIMELINE, HYDROCHLORIDE SALT

synthesis of CEVIMELINE, HYDROCHLORIDE SALT

Cevimeline Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Cevimeline Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 99)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
AFINE CHEMICALS LIMITED	+86-571-85134551 +86-18958018566	info@afinechem.com	China	15030	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Guangzhou TongYi biochemistry technology Co.,LTD		tongyibiochem@163.com	China	2988	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501	product@acmec-e.com	China	33301	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58

107233-08-9()Verwandte Suche:

Gefarnat Succimer Tetrabenazin Pilocarpin Citalopram (R)-Chinuclidin-3-ol Chinuclidin-3-olhydrochlorid

CevimelineHClSalt
(+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3quinuclidine
Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, (2'R,3R)-rel-
Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, cis-
2-methyspiro(1,3-oxathiolane-5,3)quinuclidine
AF-102B
Evoxac
SNI-2011
Cevimeline
(+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine]
Hsdb 7286
3]oxathiolane]
3R)-rel-
2-Methyspiro(1,3-oxathiol
CeviMeline(Evoxac)
AF-102B;FKS-508
rac,cis-Cevimeline
cis-2-Methyl-1'-azaspiro[[1,3]oxathiolane-5,3'-bicyclo[2.2.2]octane
Cevimeline (AF-102B)
107233-08-9
C10H18ClNOS
C10H17NOSHCl
Heterocycles
Intermediates & Fine Chemicals
Neurochemicals
Pharmaceuticals