1,2-Oxathian-2,2-dioxid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R68:Irreversibler Schaden möglich.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
1,4-Butane sultone is an impurity in sulfobutyl ether β-cyclodextrin (SBE-β-CD), and has been reported to be a weak carcinogen. 1,4-Butane sultone can be used for preparation of Brnsted acidic ionic liquids and the ionic liquid is green, highly water soluble, thermally stable, specific and catalytically stable, and can be used for the preparation of symmetrical 3,3'-diaryloxyoctanone compounds
[1-2].
Chemische Eigenschaften
Butanesultone is a viscous, clear, colourless – or yellowish/brown – and odourless liquid. When heated, vapours of butanesultone are known to form explosive mixtures with air and are reported to cause explosion hazards.
Verwenden
1,4-Butane Sultone is an alkylating agent with weak carcinogenic activity.
Application
1,4-Butane sultone is an intermediate widely used for sulfonated surfactants.It is also applied in photo development and electroplating.It is
used as the Intermediate for the production of APIs.It used in
sulfobutylether-β-cyclodextrin（SEBCD).
Chemische Reaktivität
The reactivity of 1,4-butane sultone:
Under conditions involving an excess of diol, the reaction of 1,4-butanesultone (BS) with 1,4-butanediol (BD) yields only a negligible amount of (4-hydroxybutoxy)butane-1-sulfonic acid (BDSA), and the formation of tetrahydrofuran (THF) (accounting for 30 mol% of the initial BD) is observed.
BD was reacted with Na₂CO₃, used as the base, at a molar ratio of 10:1 for 1 hour at room temperature. After distilling off the unreacted BD, BS was added. The resulting BDSS was purified by precipitation, yielding a 45% yield
[3].
Sicherheitsprofil
Suspected carcinogen
with experimental tumorigenic data. Poison
by subcutaneous, intravenous, and
intraperitoneal routes. Moderately toxic by
ingestion. Experimental reproductive
effects. Human mutation data reported. See
also SULFONATES. When heated to
decomposition it emits toxic fumes of SOx
Synthese
Performing sulfonation on 3-butylene-1-alcohol or 3-butylene-1-chlorine serving as a raw material and a sulfonating agent under the oxidation-reduction of an initiator;performing acidification after the reaction is finished;performing lactonization by high vacuum dehydration cyclization and azeotropic dehydration cyclization;and finally refining to obtain a 1,4-butane sultone finished product.
1,2-Oxathian-2,2-dioxid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
