Thalidomide-NH-CH2-COOH

927670-97-1

CAS-Nr.: 927670-97-1

Englisch Name:: Thalidomide-NH-CH2-COOH

Synonyma:: Thalidomide-NH-CH2-COOH;Thalidomide-4-NH-C1-COOH;6-dioxopiperidin-3-yl)-1;Pomalidomide acetic acid;3-dioxoisoindolin-4-yl)glycine;3-dioxoisoindol-4-yl]amino]acetic acid;Thalidomide-NH-CH2-COOH, 10 mM in DMSO;(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine;2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]acetic acid;Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

CBNumber:: CB18197022

Summenformel:: C15H13N3O6

Molgewicht:: 331.28

MOL-Datei:: 927670-97-1.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 43

Thalidomide-NH-CH2-COOH Eigenschaften

Siedepunkt:: 713.9±60.0 °C(Predicted)

Dichte: 1.637±0.06 g/cm3(Predicted)

storage temp.: 2-8°C

Löslichkeit: DMSO : 50 mg/mL (150.93 mM; Need ultrasonic)

pka: 3.92±0.10(Predicted)

Aggregatzustand: Solid

Farbe: Light yellow to green yellow

InChI: InChI=1S/C15H13N3O6/c19-10-5-4-9(13(22)17-10)18-14(23)7-2-1-3-8(12(7)15(18)24)16-6-11(20)21/h1-3,9,16H,4-6H2,(H,20,21)(H,17,19,22)

InChIKey: LRGLFYOYKPSPJQ-UHFFFAOYSA-N

SMILES: C(O)(=O)CNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

Sicherheit

Thalidomide-NH-CH2-COOH Chemische Eigenschaften,Einsatz,Produktion Methoden

Definition

Thalidomide-NH-CH2-COOH contains a thalidomide group, an amide, an alkylC2 chain, and a terminal carboxylic acid. This product is ready for conjugation to target proteins for PROTAC R&D. It is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. This compound also can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937).

Thalidomide-NH-CH2-COOH Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Thalidomide-NH-CH2-COOH Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 43)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32435	58
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8647	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39035	58
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +8613523716970	Lingzhiyue@aliyun.com	China	3145	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43339	58
Suzhou ARTK Medchem Co., Ltd.	+86-512-68323658 +86-18168183658	sales1@artkmedchem.com	China	39002	58
Shaanxi Dideu New Materials Co. Ltd	+86-18192503167 18192503167;	1036@dideu.com	China	6838	58
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	4396	65
Hangzhou J&H Chemical Co., Ltd.	0571-87396432	sales@jhechem.com	China	14909	59
Shanghai Chaolan Chemical Technology Center	021-QQ：65489617 15618227136	Sales@ATKchemical.com	China	9985	58

[(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)amino]acetic acid
Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
Thalidomide-NH-CH2-COOH
3-dioxoisoindol-4-yl]amino]acetic acid
3-dioxoisoindolin-4-yl)glycine
6-dioxopiperidin-3-yl)-1
(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine
inhibit,Ligands for E3 Ligase,E3 ligase-recruiting Moiety,Inhibitor,Thalidomide NH CH2 COOH,ThalidomideNHCH2COOH,cereblon,Thalidomide-NH-CH-2-COOH,CRBN,Thalidomide
2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]acetic acid
Thalidomide-4-NH-C1-COOH
Thalidomide-NH-CH2-COOH, 10 mM in DMSO
Pomalidomide acetic acid
927670-97-1