EPOXOMICIN

EPOXOMICIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Epoxomicin has been used:

• as an ubiquitin–proteosome system (UPS) inhibitor in pheochromocytoma PC12 cells
• as a proteasome inhibitor in mammary epithelial MCF-10A cells
• as a proteasome inhibitor in chymotryptic assay in cardiomyocytes

Definition

ChEBI: A tripeptide consisting of an Ile-Ile-Thr-NH2 sequence N-substituted on the threonamide amidic nitrogen with a (2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl group and with acetyl and meth l groups on the nitrogen of the isoleucine residue distal to the threonamide; a naturally occurring selective proteasome inhibitor with anti-inflammatory activity.

Allgemeine Beschreibung

Epoxomicin is a linear peptide consisting of a threonine or serine residue with α′, β′-epoxyketonederived from leucine or a γ,δ-dehydroleucine. It is a natural product isolated fromActinomycessp., and is a cell-permeable, potent, selective and irreversible proteasome inhibitor.

EPOXOMICIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

EPOXOMICIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9037	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49859	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501	product@acmec-e.com	China	33301	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58
Zjartspharm Co., Ltd	15068876005	jocelynpan@zjarts.com	China	9957	58

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• BU-4061T
• EPOXOMICIN, SYNTHETIC
• EPOXOMICIN
• (2R)-2-[ACETYL-(N-METHYL-L-ISOLEUCYL)-L-ISOLEUCYL-L-THREONYL-L-LEUCYL]-2-METHYLOXIRANE
• n-acetyl-n-methyl-l-isoleucyl-l-isoleucyl-n-[(1s)-3-methyl-1-[[(2r)-2-methyloxiranyl]carbonyl]butyl]-l-threoninamide
• Aids010837
• Aids-010837
• L-Threoninamide, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-
• Epoxomicin, 99.5%
• CS-1626
• Epoxomicin(BU-4061T)
• EPOXOMICIN;BU4061T;BU-4061T
• (2S,3S)-2-[[(2S,3S)-2-[acetyl(Methyl)aMino]-3-Methylpentanoyl]aMino]-N-[(2S,3R)-3-hydroxy-2-[[(2S)-4-Methyl-1-[(2R)-2-Methyloxiran-2-yl]-1-oxopentan-2-yl]aMino]butanoyl]-3-MethylpentanaMide
• N-Acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-threoninamide
• Epoxomicin, 97%, a selective proteasome inhibitor
• BU-4061T,Aids010837
• L-Threoninamide, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-
• 134381-21-8 supplier in China
• Epoxomicin, 20S proteasome inhibitor
• Epoxomicin, 10 mM in DMSO
• Epoxomicin solution
• 134381-21-8
• C28H50N4O7
• Enzymes, Inhibitors, and Substrates
• Proteasomes
• Proteasome, Calpain and Lysosomal Proteases
• Inhibitors
• BioChemical
• Biochemicals and Reagents
• Application Index
• Cell Signaling Enzymes
• peptides
• ProteasomeInhibitors