Furan-2(5H)-on
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- CAS-Nr.
- 497-23-4
- Bezeichnung:
- Furan-2(5H)-on
- Englisch Name:
- 2(5H)-Furanone
- Synonyma:
- FURANONE;FURAN-2(5H)-ONE;Butenolide;γ-Crotonolactone;2-Furanone;4-Hydroxy-2-butenoic acid gamma-lactone;CARMELAN;2-Butenolide;2H-furan-5-one;Crotonolactone
- CBNumber:
- CB3201475
- Summenformel:
- C4H4O2
- Molgewicht:
- 84.07
- MOL-Datei:
- 497-23-4.mol
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Furan-2(5H)-on Eigenschaften
- Schmelzpunkt:
- 4-5 °C (lit.)
- Siedepunkt:
- 86-87 °C/12 mmHg (lit.)
- Dichte
- 1.185 g/mL at 25 °C (lit.)
- Brechungsindex
- n20/D 1.469(lit.)
- FEMA
- 4138 | 4-HYDROXY-2-BUTENOIC ACID GAMMA-LACTONE
- Flammpunkt:
- 214 °F
- storage temp.
- 2-8°C
- Löslichkeit
- Chloroform, Ethyl Acetate (Slightly)
- Aggregatzustand
- Liquid
- Farbe
- Clear colorless to pale yellow or amber
- Geruch (Odor)
- buttery
- Geruchsart
- buttery
- Wasserlöslichkeit
- Immiscible with water.
- JECFA Number
- 2000
- BRN
- 383585
- Henry's Law Constant
- 3.5×10-1 mol/(m3Pa) at 25℃, Wang et al. (2017)
- Stabilität:
- Moisture Sensitive
- InChI
- 1S/C4H4O2/c5-4-2-1-3-6-4/h1-2H,3H2
- InChIKey
- VIHAEDVKXSOUAT-UHFFFAOYSA-N
- SMILES
- O=C1OCC=C1
- LogP
- -0.600
- CAS Datenbank
- 497-23-4(CAS DataBase Reference)
- NIST chemische Informationen
- 2(5H)-Furanone(497-23-4)
- EPA chemische Informationen
- 2(5H)-Furanone (497-23-4)
Furan-2(5H)-on Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
2(5H)-Furanone is light brown liquid
Occurrence
Reported found in coffee
Verwenden
2(5H)-Furanone is a versatile reagent used in Michael addition reactions1 for synthesis of lignans.2 Also employed in three-component Michael-Aldol reactions with an aldehyde anda thiolate3 or carbanion.4
Definition
2(5H)-Furanone is a mycotoxin that contains an α,β-unsaturated lactone moiety.
Allgemeine Beschreibung
Chiral urea compounds catalyzed hetero-Michael addition reaction of 2(5
H)-furanone (γ-crotonolactone) to pyrrolidine. The quorum sensing inhibition activity by 2(5
H)-furanone was studied using bioindicator strains.
Hazard
Extremely toxic.
läuterung methode
Fractionally distil the lactone under reduced pressure. IR: (CCl4) 1784 and 1742 cm-1, UV no max above 205nm ( 1160 cm-1 M-1) and 1HR: (CCl3) : 2.15 (pair of triplets 1H), 3.85 (pair of triplets 1H) and 5.03 (triplet 2H). [Price & Judge Org Synth Coll Vol V 255 1973, Smith & Jones Can J Chem 37 2007, 2092 1959, Beilstein 17/9 V 112.]
Furan-2(5H)-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Furan-2(5H)-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 286)Lieferanten
497-23-4(Furan-2(5H)-on)Verwandte Suche:
Furan
Furazolidon
Benzofuran
4-Methoxy-2,5-dimethylfuran-3(2H)-on
3,4-Diphenylfuran-2,5-dion
3-β,14-Dihydroxy-5-β,14-β-card-20(22)-enolid
3-(6-Desoxy-alpha-L-mannopyranosy-loxy)-1,5,11a,14,19-pentahydroxy-card-20(22)-enolid
6-O-Palmitoylascorbinsure
2,3-Didehydro-D-erythro-hexono-1,4-lacton
Cymarin
Rubratoxin B
Citraconsäureanhydrid
Digoxin
Dichlormaleinsureanhydrid
Dimethylmaleinsureanhydrid
Maleinsäureanhydrid
Digitoxin
Furaneol acetate
- .alpha.,.beta.-Crotonolactone
- γ-Crotonolactone, 2-Buten-1,4-olide
- 2,5-Dihydrofuranone
- 5-Oxo-2,5-dihydrofuran-3-yl ester
- a,b-Crotonolactone
- Crotonic acid, 4-hydroxy-
- 2,5-Dihydrofuran-2-one
- 2(5H)-Furanone,γ-Crotonolactone, 2-Buten-1,4-olide
- 2(5H)-Furanone
2-Oxo-2,5-dihydrofuran
- 2(5H)-FURANONE FOR SYNTHESIS 1 ML
- 2-Furanone
- 2(5H)-Furanone 98%
- but-2-en-4-olide
- 2H-furan-5-one
- .delta.,.alpha.,.beta.-Butenolide
- .gamma.-Crotolactone
- .gamma.-Hydroxycrotonicacidlactone
- 2(5H)-Furanone (.gamma.-crotonolactone)
- AKOS BBS-00003279
- GAMMA-CROTONOLACTONE
- CARMELAN
- 2-Buten-4-olide
- 2-Butenoic acid, 4-hydroxy-, gamma-lactone
- 2-Butenoic acid-gamma-lactone
- 2-Butenoicacid,4-hydroxy-,.gamma.-lactone
- 2-Butenoicacid.gamma.-lactone
- 2-butenoicacidgamma-lactone
- 2-Butenolide
- 2-Oxo-2,5-dihydrofuran(2-[5H]-furanone)
- 4-Hydroxy-2-butenoic acid lactone
- 4-Hydroxy-2-butenoicacid.gamma.-lactone
- 4-hydroxy-2-butenoicacidgamma-lactone
- 4-Hydroxy-2-butenoicacidlactone
- 4-hydroxy-2-butenoicacigamma-lactone
- 4-hydroxy-crotonicacigamma-lactone
- 5H-Furan-2-one
- alpha,beta-Crotonolactone
- Crotonic acid, 4-hydroxy-, gamma-lactone
- Crotonicacid,4-hydroxy-,.gamma.-lactone
- Crotonolactone
- delta,alpha,beta-Butenolide
- gamma-Crotolactone
- gamma-Hydroxycrotonic acid lactone
- gamma-hydroxycrotonicacidlactone
- Isocrotonolactone
- 2-BUTEN-1,4-OLIDE
- 2-OXO-2,5-DIHYDROFURAN
- 2(5H)-FURANONE
- 2,5-DIHYDRO-2-FURANONE
- 2(5H)-Furanone,98%
- 5-HYDROFURAN-2-ONE
- 2-Buten-1,4-olide~gamma-Crotonolactone
- g-Crotonolactone
- γ-Crotonolactone>
- 2(5H)-Furanone 497-23-4
- γ-Crotonolactone
- Ramelteon Impurity 41
- 2(5H)-Furanone
