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Ponesterone A

Ponesterone A Struktur
13408-56-5
CAS-Nr.
13408-56-5
Englisch Name:
Ponesterone A
Synonyma:
PONASTERONE A;(2S,3R,5R,9R,10R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one;ponesterone A;25-DEOXYECDYSTERONE;Ponasterone A, >=98%;25-DEOXY-20-HYDROXYECDYSONE;Ponasterone A, Ecdysone analog;2B,3B,14A,20R,22R-PENTAHYDROXY-5B-CHOLEST-7-EN-6-ONE;2β,3β,14α,20r,22r-pentahydroxy-5β-cholest-7-en-6-one;(20R,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7-ene-6-one
CBNumber:
CB4155274
Summenformel:
C27H44O6
Molgewicht:
464.63
MOL-Datei:
13408-56-5.mol
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Ponesterone A Eigenschaften

Schmelzpunkt:
259-260° (dec)
alpha 
D15 +90° (methanol)
Siedepunkt:
640.5±55.0 °C(Predicted)
Dichte
1.22±0.1 g/cm3(Predicted)
storage temp. 
−20°C
Löslichkeit
Methanol (Slightly, Sonicated), Pyridine (Slightly)
pka
14.13±0.70(Predicted)
Aggregatzustand
White to off-white powder.
Farbe
White to Off-White
Biologische Quelle
synthetic (organic)
InChIKey
PJYYBCXMCWDUAZ-JJJZTNILSA-N
SMILES
C12=CC([C@]3([H])C[C@@H](O)[C@@H](O)C[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21O)[C@](O)(C)[C@H](O)CCC(C)C)=O |&1:3,6,8,11,13,17,19,22,24,27,r|
CAS Datenbank
13408-56-5(CAS DataBase Reference)

Sicherheit

WGK Germany  3
Speicherklasse 11 - Combustible Solids

Ponesterone A Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ponesterone A, a steroidal compound, falls under the category of ecdysone and can be found in various sources throughout nature. It was first isolated from insect plants by Nakanishi and Horm in 1966. Compared to β-ecdysone, Ponesterone proves to be 3-100 times more potent in specific neurosensory systems.

Biochem/physiol Actions

Ponasterone A is an analogue of ecdysone. It induced death of non-adapted insects may be related to PoA regulating different set of genes when compared to 20E.

Ponesterone A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Ponesterone A Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • 2β,3β,14α,20r,22r-pentahydroxy-5β-cholest-7-en-6-one
  • 2B,3B,14A,20R,22R-PENTAHYDROXY-5B-CHOLEST-7-EN-6-ONE
  • 2BETA, 3BETA, 14ALPHA, 20R,22R-PENTAHYDROXY-5BETA-CHOLEST-7-EN-6-ONE
  • 25-DEOXY-20-HYDROXYECDYSONE
  • 25-DEOXYECDYSTERONE
  • Ponasterone A, >=98%
  • 25-Deoxy-20-hydroxyecdysone, 25-Deoxyecdysterone, 2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one
  • (20R,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7-ene-6-one
  • (20R,22R)-2β,3β,14α,20β,22α-Pentahydroxy-5β-cholesta-7-ene-6-one
  • Cholest-7-en-6-one, 2,3,14,20,22-pentahydroxy-, (2β,3β,5β,22R)-
  • gene,ecdysone,ecdysteroid,25-Deoxyecdysterone,expression,inhibit,Ponasterone A,Inhibitor
  • ponesterone A
  • Ponasterone A, Ecdysone analog
  • (2S,3R,5R,9R,10R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
  • PONASTERONE A
  • 13408-56-5
  • C27H44O6
  • Hormones
  • Other Steroid Products
  • Cytokines, Growth Factors and Hormones
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Steroid Hormones
  • Steroids
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