5-Bromindol
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- CAS-Nr.
- 10075-50-0
- Bezeichnung:
- 5-Bromindol
- Englisch Name:
- 5-Bromoindole
- Synonyma:
- 5-BROMO-1H-INDOLE;5-BI;SW-43;SWF-43;B2310G25;5-Bromindole;5-BROMOINDOLE;5-bromonindole;Bromoindole-99%;5-Bromide indole
- CBNumber:
- CB4164351
- Summenformel:
- C8H6BrN
- Molgewicht:
- 196.04
- MOL-Datei:
- 10075-50-0.mol
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5-Bromindol Eigenschaften
- Schmelzpunkt:
- 90-92 °C (lit.)
- Siedepunkt:
- 228.5°C (rough estimate)
- Dichte
- 1.5466 (rough estimate)
- Brechungsindex
- 1.6550 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Löslichkeit
- 126mg/l (calculated)
- Aggregatzustand
- Powder or Chunks
- pka
- 16.04±0.30(Predicted)
- Farbe
- White to light brown
- BRN
- 112877
- InChI
- InChI=1S/C8H6BrN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H
- InChIKey
- VXWVFZFZYXOBTA-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(Br)C=C2)C=C1
- CAS Datenbank
- 10075-50-0(CAS DataBase Reference)
- EPA chemische Informationen
- 1H-Indole, 5-bromo- (10075-50-0)
5-Bromindol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
white to light brown powder or chunks
Verwenden
A potential inhibitor of GSK-3
Application
The 5-bromoindole is an important medicine intermediate that produces important source material for preventing and treating medicines such as cardiovascular disorders, sacred diseases, tumours and strengthening immunity. one of its important uses is the synthesis of indole derivative as tryptamines compounds, etc. These indole derivativeses are closely related with human vital movement, wherein melatonin and verivate thereof are regulated circadian rhythm, sleep, aspect such as antitumor very effectively.
läuterung methode
Purify it by steam distillation from a faintly alkaline solution. Cool the aqueous distillate, collect the solid, dry it in a vacuum desiccator over P2O5 and recrystallise it from aqueous EtOH (35% EtOH) or pet ether/Et2O. UV in MeOH has at 279, 287 and 296nm (log 3.70, 3.69 and 3.53). The picrate has m 137-138o(dec) (from max Et2O/pet ether). [UV: Thesing et al. Chem Ber 95 2205 1962, UV and NMR: Lallemand & Bernath Bull Soc Chim Fr 4091 1970, Beilstein 20/7 V 36.]
5-Bromindol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-Bromindol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 859)Lieferanten
10075-50-0(5-Bromindol)Verwandte Suche:
- 5-BROMOINDOLE
- 5-BI
- 5-BROMO-1H-INDOLE
- 5-Bromindole
- 5-bromonindole
- 5-Bromide indole
- Bromoindole-99%
- 5-Bromoindole99%
- 5-Bromoindole 99%
- 5-BROMOBENZOTHOAZOLE
- 5-BROMOINDAN-1-ONE
- 5-BROMO INDOLE pure
- 1H-Indole, 5-bromo-
- 5-BroMoindole, 99% 5GR
- 5-broMo-2H-indole
- 5-BroMoindole (KSM-II)
- 5-broMinatedindole
- 5-broMine indole
- 1H-Indole, 5-bromo- (9CI)
- B2310G25
- RARECHEM AH BS 0082
- 5-Bromoindole in stock Factory
- 5-Bromo-1H-indole 99%
- 5-Bromoindole COA TDS MSDS
- 5-Bromoindole TDS Free Sample
- 5-Bromoindole >
- SWF-43
- SW-43
- 5-Bromoindole, 98%
- 10075-50-0
- 10070-50-0
- 10075-50-5
- Indoles
- Simple Indoles
- Heterocyclic Building Blocks
- Halogenated Heterocycles
- Building Blocks
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- IndolesBuilding Blocks
- Organohalides
- Simple Indoles
- Pyrroles & Indoles
- Heterocycle-Indole series
- Indoles
- Pharmaceutical Intermediates
- Indole Derivatives
- Indole/indoline/oxindole
- Indoles and derivatives
- IndoleDerivative
- Halides
- Pyrroles & Indoles
- Indole
- blocks
- Bromides
- IndolesOxindoles
- bc0001
