Fmoc-Gly-OH
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- CAS-Nr.
- 29022-11-5
- Englisch Name:
- Fmoc-Gly-OH
- Synonyma:
- FMOC-GLY-OH;FMOC-GLY;FMOC-L-GLY-OH;FMOC-L-GLY;FMOC-GLYCINE;Fmoc-g;Fmoc-GL;Fomc-Gly-OH;FMOC-L-GLYCINE;N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]GLYCINE
- CBNumber:
- CB4288480
- Summenformel:
- C17H15NO4
- Molgewicht:
- 297.31
- MOL-Datei:
- 29022-11-5.mol
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Fmoc-Gly-OH Eigenschaften
- Schmelzpunkt:
- 174-175 °C(lit.)
- Siedepunkt:
- 438.82°C (rough estimate)
- Dichte
- 1.1671 (rough estimate)
- Brechungsindex
- 1.4500 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- almost transparency in Methanol
- Aggregatzustand
- Powder
- pka
- 3.89±0.10(Predicted)
- Farbe
- White
- BRN
- 2163967
- Major Application
- peptide synthesis
- InChI
- InChI=1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20)
- InChIKey
- NDKDFTQNXLHCGO-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
- CAS Datenbank
- 29022-11-5(CAS DataBase Reference)
Fmoc-Gly-OH Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
Fmoc-Gly-OH is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.
synthetische
Glycine (Gly) (0.5 g, 6.66 mmol) was dissolved in 10% NaCO
3 (14 ml) under stirring in a 50-ml flask. To the resulting solution, which had been put into an ice bath, 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl) (1.72 g, 6.66 mmol) in dioxane (12 ml) was gradually added. The reaction mixture was stirred at room temperature for 4 hours. Then added water (150 ml) to the mixture. The aqueous phase layer was separated from the reaction mixture and stripped with ether three times (75 ml×3). The stripped aqueous layer was acidified with 2N HCl aqueous solution to a pH=2, followed by extraction with ethyl acetate three times (75 ml×3). The organic phase layer was recovered and concentrated to obtain crude product of 1.70 g. The crude product was recrystallized in a mixed solvent of ethyl acetate hexane=1:2 (30 ml), and white solid denoted as Fmoc-Gly-OH was obtained after filtration at a reduced pressure.
Allgemeine Beschreibung
Fmoc-Gly-OH is used for fmoc solid-phase peptide synthesis.
Fmoc-Gly-OH Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Fmoc-Gly-OH Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 673)Lieferanten
29022-11-5()Verwandte Suche:
- 9-FLUORENYLMETHOXYCARBONYL-GLYCINE
- FMOC-GLY-OH
- F-FMOC-GLYCINE
- N-alpha-(9-fluorenylmethyloxycarbonyl)-L-glycine
- FMOC-Glycine,98%
- Fmoc-glycine
N-(9-Fluorenylmethoxycarbonyl)-glycine
- N-Fmoc-glycine
Fmoc-Gly-OH
- FMoc-DL-Glycine
- FMoc-Gly-OH >=98.0% (T)
- GLYCINE-N-FMOC (13C2,15N)
- GLYCINE-N-FMOC (13C2,2,2-D2,15N)
- N-(fluoren-9-ylmethoxycarbonyl)glycine
- Fmoc-glycine≥ 99% (HPLC)
- N-(9-Fluorenylmethoxycarbonyl)-glycine for synthesis
- (9H-Fluoren-9-yl)MethOxy]Carbonyl Gly-OH
- FMOC-GLY-OH(29022-11-5)
- FMOC-Gly-OH 98%
- npc14692
- N-ALPHA-FMOC-GLYCINE
- N-(9-FLUORENYLMETHOXYCARBONYL)-GLYCINE
- N-9-FMOC-L-GLYCINE
- N-9-FLUORENYLMETHYLOXYCARBONYLGLYCINE
- N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-GLYCINE
- N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-GLYCINE
- N-FMOC-GLYCINE
- N-FMOC-L-GLYCINE
- 2-[(9H-Fluorene-9-yl)methoxycarbonylamino]acetic acid
- N-[(9H-Fluorene-9-yl)methoxycarbonyl]glycine
- Glycine-1-13C-N-FMOC
- Glycine-2-13C-N-FMOC
- Glycine-UL-13C2,15N-N-FMOC
- Fmoc-Gly-OH (Fmoc-Glycine)
- FMOC-GLYCINE-OH
- glutanmic acid
- FMOC-L-GLYCINE extrapure
- Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- N-(9-Fluorenylmethoxycarbonyl)glycine ,98%
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine>
- FMOC-GLY-OH 25 G
- FMOC-GLY-OH 100 G
- FMOC-GLY-OH 250 G
- FMOC-Glycine USP/EP/BP
- FMOC-Glycine extrapure, 99%
- Fmoc-glycocoll
- N-Fmoc-glycine, 95%
- FMOC-L-GLYCINE
- FMOC-L-GLY-OH
- FMOC-GLYCINE
- Fmoc-GL
- Fmoc-Gly-OH Fmoc-Gly-OH
- FMOC-L-GLY
- FMOC-GLY
- Fmoc-g
- Fomc-Gly-OH
- N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]GLYCINE
- 29022-11-5
- 29011-11-5
- 26022-11-5
