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2-Naphthacencarboxamid, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochlorid, [4S-(4α,4aα,5α,5aα,6α,12aα)]-

Doxycycline hydrochloride Struktur
10592-13-9
CAS-Nr.
10592-13-9
Bezeichnung:
2-Naphthacencarboxamid, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochlorid, [4S-(4α,4aα,5α,5aα,6α,12aα)]-
Englisch Name:
Doxycycline hydrochloride
Synonyma:
DOXYCYCLINE HCL;Hyclate;DOXYCYCLINE HYDROCHLORIDE HEMIETHANOLATE HEMIHYDRATE;Doxycyclini Hyclas;DOXYCYCLINE HYCLATE HYDRATE;DoxycChemicalbookyclinehydrochloride;Doxycycline Hydrochloride, Ready Made Solution;retens;ecodox;novadox
CBNumber:
CB4489445
Summenformel:
C22H25ClN2O8
Molgewicht:
480.9
MOL-Datei:
10592-13-9.mol
Request For Quotation

2-Naphthacencarboxamid, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochlorid, [4S-(4α,4aα,5α,5aα,6α,12aα)]- Eigenschaften

Schmelzpunkt:
195-201℃
Flammpunkt:
87℃
storage temp. 
Inert atmosphere,2-8°C
Löslichkeit
H2O: 50 mg/mL, clear, yellow-green
Aggregatzustand
powder
Farbe
yellow
Biologische Quelle
synthetic
Wasserlöslichkeit
Soluble in water.
BCS Class
1
InChIKey
RUYHIJHUVHIMIR-PGTYNCOMNA-N
SMILES
O[C@@]12C(C(C(=O)N)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]([C@]1([H])[C@H](C3C=CC=C(O)C=3C(=O)C1=C2O)C)O)=O.Cl |&1:1,9,13,15,16,18,r|
CAS Datenbank
10592-13-9(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn,Xi
R-Sätze: 22-36/37/38
S-Sätze: 26-36/37
RIDADR  NA 1993 / PGIII
WGK Germany  3
F  8
HS Code  29413000
Speicherklasse 10 - Combustible liquids
Bildanzeige (GHS) Exclamation Mark (GHS07)Health Hazard (GHS08)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P308+P313 BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

2-Naphthacencarboxamid, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochlorid, [4S-(4α,4aα,5α,5aα,6α,12aα)]- Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

Chemische Eigenschaften

Yellow Crystalline powder

Verwenden

Doxycycline hydrochloride is a salt prepared from doxycycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.

Definition

ChEBI: The hydrochloride salt of doxycycline.

2-Naphthacencarboxamid, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochlorid, [4S-(4α,4aα,5α,5aα,6α,12aα)]- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

5-Sulfosalicylsure Glucose Ethanol oxytetracyclin Chinaldin Strke Acetanilid Doxycyclin Hydrogenchlorid Wasser

Downstream Produkte

Doxycycline monohydrate

2-Naphthacencarboxamid, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochlorid, [4S-(4α,4aα,5α,5aα,6α,12aα)]- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 528)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi TNJONE Pharmaceutical Co., Ltd

sarah@tnjone.com China 1081 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325
sales1@chuanghaibio.com China 5214 58
shandong perfect biotechnology co.ltd 		+86-53169958659 +86-13153181156
 sales@sdperfect.com China 293 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		+86-15350851019; +86-15383190639
 admin@86-ss.com China 999 58
Shaanxi Xianhe Biotech Co., Ltd 		+86-17709210191; +86-17709210191
 Jerry@xhobio.com China 901 58
Hefei Lbao Physical & Chemical Science Co.,Ltd 		+1-5184799099;
lbaochemicals@gmail.com China 670 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21533 55
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +86-18949832763
 info@tnjchem.com China 2984 55
career henan chemical co 		+86-0371-86658258
sales@coreychem.com China 29766 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19935 58

10592-13-9(2-Naphthacencarboxamid, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochlorid, [4S-(4α,4aα,5α,5aα,6α,12aα)]-)Verwandte Suche:

N,N-Dimethylpyridin-4-amin Topotecan hydrochloride 1,4-Dioxan Oxytetracycline dihydrate N,N-Dimethyl-1,3-diaminopropan 4-Dimethylamino-benzaldehyd Demeclocyclinhydrochlorid (8S-cis)-10-[(3-Amino-2,3,6-tridesoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacen-5,12-dionhydrochlorid Doxorubicin hydrochloride 4-Dimethylaminobenzoesure Doxycyclin 2-Dimethylaminoethanol oxytetracyclin Naphthacen Doxycycline hyclate 2-Naphthacencarboxamid, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochlorid, [4S-(4α,4aα,5α,5aα,6α,12aα)]-
  • 11-Hydroxy-5-methyl-2-(1,2-dihydroxy-1-oxiranylethyl)-4H-anthra[1,2-b]pyran-4,7,12-trione
  • Doxycycline hyclate,Doxycycline hydrochloride hemiethanolate hemihydrate
  • 6- Deoxy-5-hydroxytetracycline hydrochloride, 6-Deoxyoxytetracycline hydrochloride, Doxytetracycline hydrochloride
  • Thedoxycycline hydrochloride
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,6R,12aS)-
  • Doxycycline Hydrochloride, Ready Made Solution
  • liomycin
  • mespafin
  • midoxin
  • nivocilin
  • novadox
  • retens
  • roximycin
  • DOXYCYCLINI HYDROCHLORIDUM
  • DOXYCYCLINE HYDROCHLORIDE
  • 2-(AMINO-HYDROXY-METHYLIDENE)-4-DIMETHYLAMINO-5,10,11,12A-TETRAHYDROXY-6-METHYL-4A,5,5A,6-TETRAHYDRO-4H-TETRACENE-1,3,12-TRIONE
  • ALPHA-6-DEOXY-5-HYDROXYTETRACYCLINE
  • Doxycycline Hydrochloride Anhydrous
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha)]-
  • Doxycicline Hcl
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride (8CI)
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,6α,12aα)]-
  • 2-Naphthacenecarboxamide, 4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (6CI)
  • 6-Deoxyoxytetracycline hydrochloride
  • 6-Desoxy-5-hydroxytetracycline hydrochloride
  • Deoxy-5-hydroxytetracycline hydrochloride
  • Deoxyoxytetracycline hydrochloride
  • Doxylin
  • Idocyklin
  • Vibramycin hydrochloride
  • α-6-Deoxy-5-hydroxytetracycline hydrochloride
  • (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
  • VIBRAMYCIN, HCL
  • ,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride
  • biocamycin
  • doxigalumicina
  • doxy-ii
  • doxy-tablinen
  • ecodox
  • hydramycin
  • samecin
  • tanamicin
  • tecacin
  • tetradox
  • vibradox
  • vibramycinhyclate
  • vibra-tabs
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro- 3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
  • Dossiciclina Iclato
  • 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
  • Paldomycin
  • Piperamycin
  • Rasenamycin
  • DOXYCYCLINE 5G
  • -6-Deoxy-5-hydroxytetracycline Hydrochloride
  • oxycyclineHCl
  • Doxycycline Hydrochloride Discontinued. Please see D561500.
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