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N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1)

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Struktur
1374744-69-0
CAS-Nr.
1374744-69-0
Englisch Name:
N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1)
Synonyma:
CL121;TG101348(2ClH.H2O);Fedratinib HCl hydrate;Fedratinib Hydrochloride;Fedratinibdihydrochloride;TG-101348 hydrochloride hydrate;Fedratinib HCl hydrate，TG101348;Fedratinib hydrochloride hydrate;SAR 302503 hydrochloride hydrate;TG-101348 dihydrochloride hydrate
CBNumber:
CB52651162
Summenformel:
C27H40Cl2N6O4S
Molgewicht:
615.6153
MOL-Datei:
1374744-69-0.mol
Request For Quotation

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Eigenschaften

Löslichkeit
DMSO:250.0(Max Conc. mg/mL);409.09(Max Conc. mM)
Aggregatzustand
Solid
Farbe
White to yellow
InChIKey
QAFZLTVOFJHYDF-UHFFFAOYSA-N
SMILES
C1(S(NC(C)(C)C)(=O)=O)=CC=CC(NC2C(C)=CN=C(NC3=CC=C(OCCN4CCCC4)C=C3)N=2)=C1.[H]O[H].[H]Cl.[H]Cl

Sicherheit

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A potent, highly selective and ATP-competitive JAK2 inhibitor with an IC50 of 3 nM for JAK2 and JAK2V617F.

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 52)Lieferanten
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TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354
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InvivoChem 		+1-708-310-1919 +1-13798911105
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TargetMol Chemicals Inc. 		+1-781-999-5354;
support@targetmol.com United States 39031 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8615965530500
 nickzhang@hangyubiotech.com China 10997 58
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Amadis Chemical Company Limited 		571-89925085
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Shanghai Thunder Biological Technology Co., Ltd. 18621609968
 1162686636@qq.com China 830 58
  • CL121
  • N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1)
  • TG101348(2ClH.H2O)
  • TG-101348 dihydrochloride hydrate
  • N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate
  • Fedratinib hydrochloride hydrate
  • N-(tert-Butyl)-3-((5-methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)amino)benzenesulfonamide dihydrochloride hydrate
  • Fedratinib (TG101348) dihydrochloride hydrate
  • SAR 302503 hydrochloride hydrate
  • TG-101348 hydrochloride hydrate
  • Fedratinib Hydrochloride
  • Fedratinib HCl hydrate，TG101348
  • Fedratinib dihydrochloride monohydrate
  • Fedratinibdihydrochloride
  • STAT5,JAK2V617F,myeloproliferative,TG-101348 hydrochloride,Janus kinase,phosphorylation,anti-proliferation,FLT3,Apoptosis,inhibit,RET,orally,JAK,SAR 302503 hydrochloride,Fedratinib hydrochloride hydrate,anti-cancer,JAK2,Inhibitor,Fedratinib hydrochloride
  • Fedratinib HCl hydrate
  • Fedratinib hydrochloride hydrate, 10 mM in DMSO
  • 1374744-69-0
  • C27H36N6O3S2HClH2O
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