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Etelcalcetide

Etelcalcetide Struktur
1262780-97-1
CAS-Nr.
1262780-97-1
Englisch Name:
Etelcalcetide
Synonyma:
Parsavib;Etelcalcetide;AMG-416 (Velcalcetide);D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine;S-(((S)-2-Acetamido-3-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-amino-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-oxopropyl)thio)-L-cysteine
CBNumber:
CB53154325
Summenformel:
C38H73N21O10S2
Molgewicht:
1048.25
MOL-Datei:
1262780-97-1.mol
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Etelcalcetide Eigenschaften

Dichte
1.58±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
Soluble in DMSO
pka
2.01±0.10(Predicted)
Sequenz
H-Cys(1)-OH,Ac-D-Cys(1)-D-Ala-D-Arg-D-Arg-D-Arg-D-Ala-D-Arg-NH2(Disulfide bridge Cys1-(D-Cys1))/C(1),Ac-（D-C（1）-（D-A）-（D-R）-（D-R）-（D-R）-（D-A）-（D-R）-NH2(Disulfide bridge Cys1-(D-Cys1))
InChIKey
HQGWMVNIZKNABK-TZUZSESWNA-N

Sicherheit

Etelcalcetide Chemische Eigenschaften,Einsatz,Produktion Methoden

Mechanism of action

Etelcalcetide is a calcimimetic agent that allosterically modulates the calcium-sensing receptor (CaSR). Etelcalcetide binds to the CaSR and enhances activation of the receptor by extracellular calcium. Activation of the CaSR on parathyroid chief cells decreases PTH secretion.

Etelcalcetide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Etelcalcetide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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1262780-97-1()Verwandte Suche:

Sincalid Protirelin
  • Etelcalcetide
  • D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine
  • AMG-416 (Velcalcetide)
  • Parsavib
  • S-(((S)-2-Acetamido-3-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-amino-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-oxopropyl)thio)-L-cysteine
  • 1262780-97-1
  • C38H73N21O10S2
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