Procaine penicilline G hydrate
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- CAS-Nr.
- 6130-64-9
- Englisch Name:
- Procaine penicilline G hydrate
- Synonyma:
- PROCAINE PENICILLIN;Penicillin G procaine salt hydrate,Benzylpenicillin procaine salt, Procaine penicilline G hydrate;D02461;mylipen;neoproc;wycillin;afsillin;kabipenin;pen-fifty;cilicaine
- CBNumber:
- CB5334892
- Summenformel:
- C29H38N4O6S
- Molgewicht:
- 570.71
- MOL-Datei:
- 6130-64-9.mol
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Procaine penicilline G hydrate Eigenschaften
- Schmelzpunkt:
- 106-110° (with decompn)
- Dichte
- 1.255-1.256
- storage temp.
- Refrigerator
- Löslichkeit
- Slightly soluble in water, sparingly soluble in ethanol (96 per cent).
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Major Application
- pharmaceutical (small molecule)
- InChIKey
- WHRVRSCEWKLAHX-RLWRCNEPNA-N
- SMILES
- C(C1C=CC(N)=CC=1)(=O)OCCN(CC)CC.C([C@H]1C(S[C@]2([H])[C@H](NC(=O)CC3C=CC=CC=3)C(=O)N12)(C)C)(=O)O |&1:18,21,23,r|
- CAS Datenbank
- 6130-64-9(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
42/43 |
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| S-Sätze: |
36 |
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| WGK Germany |
WGK 1 |
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| RTECS-Nr. |
XH9450000 |
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| HS Code |
2941102000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Skin Sens. 1 |
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| Toxizität |
LD50 s.c. in mice: 2.3 g/kg (Soehring) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
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P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
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Procaine penicilline G hydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R42/43:Sensibilisierung durch Einatmen und Hautkontakt möglich.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White Solid
Verwenden
Procaine penicilline G hydrate is a composed of the β-lactam antibiotic of Penicillin G and the sodium channel blocker Procaine. As an antibiotic, Penicillin G is noted to posses effectiveness mainly against gram-positive organisms. Procaine Penicillin G is used a growth stimulant for poultry.
Antimicrobial activity
The procaine salt of benzylpenicillin. Poorly soluble (1:200 in
water). Administered intramuscularly as a suspension of crystals
which slowly dissolve at the site of the injection.
It must not be given intravenously. Intramuscular administration
produces a flat sustained plasma concentration of
penicillin, which is much lower than that achieved by an
equivalent dose of benzylpenicillin, with plasma levels still
detectable 24 h later. An injection of 0.6 g yields a peak plasma
concentration of 1–2 mg benzylpenicillin/L after 2–4 h. Free
procaine is detectable in the plasma within 30 min.
Very severe and potentially fatal reactions resembling those
of anaphylactic shock, but non-allergic in character, may
occur, probably due to accidental entry into the vascular system
at the site of injection and blockage of pulmonary and
cerebral capillaries by crystals of the suspension. Reactions
due to liberated procaine may include acute anxiety, hypertension,
tachycardia, vomiting, audiovisual hallucinations and
acute psychotic disturbance. The most severe reactions lead
to convulsions and cardiac arrest. Other reactions are those to
liberated benzylpenicillin.
Procaine penicilline G hydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Procaine penicilline G hydrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 106)Lieferanten
6130-64-9()Verwandte Suche:
- abbocillin-dc
- crysticillin
- despacilina
- distaquaine
- duracillin
- enylacetamido)-,compd.with2-(diethylamino)ethylp-aminobenzoate(1:1),mono
- flo-cillin
- flo-cillinaqueous
- kabipenin
- ledercillin
- mylipen
- neoproc
- novocainepenicillin
- parencillin
- penaquacaineg
- pen-fifty
- penicillingcompd.with2-(diethylamino)ethylp-aminobenzoatehydrate
- penicillingprocainehydrate
- premocillin
- procainebenzylpenicillinatehydrate
- procainepenicillinghydrate
- procainepenicillingmonohydrate
- procanodia
- prostabillin
- sharcillin
- wycillin
- PENICILLIN G PROCAINE SALT
- PENICILLIN-G PROCAIN
- Procaine penicilline G hydrate
- 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxilicacid,3,3-dimethyl-7-oxo-6-(2-ph
- 4-Thia-1-azabicyclo3.2.0heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(phenylacetyl)amino- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1), monohydrate
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)- (2S-(2alpha,5alpha,6beta))-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1), monohydrate (9CI)
- (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 2-diethylaminoethyl 4-aminobenzoate hydrate
- BENXYLPENICILLIN PROCAINE SALT
- Benzylpenicillin procaine salt, Procaine penicilline G hydrate
- Penicillin G hydrate procaine salt
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- [2S-(2.alpha.,5.alpha.,6.beta.)]-, compound with 2-(diethylamino)ethyl 4-aminobenzoate (1:1), monohydrate
- Benzylpenicillin procaine salt
- D02461
- Duracillin (tn)
- Penicillin G procaine (usp)
- Penicillin G Procaine (200 mg)
- Penicillin G Procaine COS/CGMP
- Penicillin G procaine salt hydrate
- afsillin
- ampin-penicillin
- aquacillin
- aquasuspen
- avloprocil
- benzylpenicillinicacidprocainesalthydrate
- benzylpenicillinprocainemonohydrate
- cilicaine
- 2-(diethylamino)ethyl 4-aminobenzoate (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
- Procaine penicilline G hydrate USP/EP/BP
- Penicillin G procaine (PGP)
- Penicillin G Procaine (1502552)
- Procaine penicillin hydrate
- Procaine penicilline G
