Arbidol hydrochloride
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- CAS-Nr.
- 131707-23-8
- Englisch Name:
- Arbidol hydrochloride
- Synonyma:
- Umifenovir hydrochloride;Umifenovir HCl;ARBIDOL HCL;Abidol;Doxetine;Abiduoer.HCI;Arbidole HCl;yansuanabiduoer;Soluble Arbidol;Arbidol hydrochlorid
- CBNumber:
- CB5438596
- Summenformel:
- C22H26BrClN2O3S
- Molgewicht:
- 513.88
- MOL-Datei:
- 131707-23-8.mol
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Arbidol hydrochloride Eigenschaften
- Schmelzpunkt:
- 133-137C
- storage temp.
- -20°C
- Löslichkeit
- DMSO: soluble20mg/mL protein, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
- Stabilität:
- Hygroscopic
- InChI
- InChI=1S/C22H25BrN2O3S.ClH/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;/h6-11,26H,5,12-13H2,1-4H3;1H
- InChIKey
- OMZHXQXQJGCSKN-UHFFFAOYSA-N
- SMILES
- C(C1=C(N(C)C2=CC(Br)=C(O)C(CN(C)C)=C12)CSC1C=CC=CC=1)(=O)OCC.Cl
- CAS Datenbank
- 131707-23-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi |
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| R-Sätze: |
36/38 |
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| S-Sätze: |
26 |
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| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Eye Irrit. 2
Skin Irrit. 2 |
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| Toxizität |
guinea pig,LD50,oral,> 3gm/kg (3000mg/kg),Drugs of the Future. Vol. 17, Pg. 1079, 1992. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
| P332+P313 |
Bei Hautreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
| P337+P313 |
Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
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Arbidol hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Umifenovir is a broad-spectrum antiviral agent. It inhibits the replication of H5N1 influenza (IC
50 = 30 μg/ml) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
in vitro (IC
50 = 3.537 μM). Umifenovir inhibits entry of hepatitis C virus (HCV) pseudoparticles in Huh7 cells (IC
50 = 6 μg/ml) and inhibits Zika virus protein synthesis in Vero cells.
In vivo, umifenovir (45 mg/kg) reduces the formation of influenza-induced lung lesions in ferrets.
Chemische Eigenschaften
Off White to Pale Yellow Solid
Verwenden
Arbidol hydrochloride (ARB) is a small monocular compound. It is used to prevent severe pneumonia and virus-associated cytokine dysregulation induced by influenza viruses (IFV). ARB also possesses some immunomodulatory properties, including the effects of interferon induction and macrophage activation.
Arbidol is a broad-spectrum antiviral that has demonstrated activity against a number of enveloped and non-enveloped viruses, and is used clinically to treat influenza. Arbidol inhibits viral entry into host cell and stimulates immune response. Arbidol inhibits fusion between the viral capsid and the cell membrane of the target cell, thus preventing viral entry.
Arbidol hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Arbidol hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 476)Lieferanten
131707-23-8()Verwandte Suche:
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5,11-Dihydro-11-[(4-methylpiperazin-1-yl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-ondihydrochlorid
Robenidinhydrochlorid
- 1H-INDOLE-3-CARBOXYLIC ACID, 6-BROMO-4-[(DIMETHYLAMINO)METHYL]-5-HYDROXY-1-METHYL-2-[(PHENYLTHIO)METHYL]-, ETHYL ESTER, MONOHYDROCHLORIDE
- 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1h-indole-3-carboxylic acid ethyl ester monohydrochloride
- ARBIDOL HYDROCHLORIDE
- Arbidol hydrochloride hydrate
- ARBIDOLHYDROCHLORIDE(FORR&DONLY)
- HYDROCHLORIDEOFETHYL6-BROMO-4-((DIMETHYLAMINO)METHYL)-5.
- 1h-indole-3-carboxylic acid, 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-, ethyl ester, monohydrochloride, hydrate
- 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-,1H-indole-3-carboxylic Acid Ethyl Ester Hydrochloride
- 6-bromo-4-[(dimethykamino)methyl]-5-hydroxy-1-methyl-2[(phenylthio)-methy]-1H-indol-3-carboxylata hydrochloride
- Abiduoer.HCI
- 6-bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-[(phenylthio)methyl]indole-3-carboxylic acid ethyl ester hydrate hydrochloride
- ethyl 6-bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate hydrate hydrochloride
- Arbidol & Arbidol Hydrochloride
- ethyl 6-broMo-4-[(diMethylaMino)Methyl]-5-hydroxy-1-Methyl-2-[(phenylsulfanyl)Methyl]-1H-indole-3-carboxylate hydrochloride
- Ethyl 6-broMo-4-((diMethylaMino)Methyl)-5-hydroxy-1-Methyl-2-((phenylthio)Methyl)-1H-indole-3-carboxylate hydrochloride
- Ethyl 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-car
- Doxetine
- Arbidol hydrochloride (Umifenovir hydrochloride)
- 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid ethyl ester, hydrochloride (1:1)
- Arbidol hydrochloride
6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid ethyl ester monohydrochloride
- Arbidol Hydrochloride solution,100ppm
- Ethyl 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-
- Arbidole HCl
- (3S,4S,5R)-5-(hydroxymethyl)dihydrofuran-2,2,3,4(3H)-tetraol hydrochloride
- Arbidol HCl 131707-23-8
- Arbidol hydrochloride###131707-23-8
- yansuanabiduoer
- Arbidol hydrochloride, Umifenovir
- ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate,hydrochloride
- Soluble Arbidol
- Arbidol/Arbidol hydrochloride/Arbidol hcl
- Abidol
- Arbidol/Umifenovir Hydrochloride
- hot selling Sultamicillin
- Arbidol hydrochloride USP/EP/BP
- Arbidol HCl (Umifenovir)
- 99% Pure Pharmaceutical Grade CAS 131707-23-8 Arbidol HCl/Arbidol Hydrochloride
- Umifenovir (Arbidol) HCl
- Arbidol-d6Q: What is
Arbidol-d6 Q: What is the CAS Number of
Arbidol-d6
- Arbidol hydrochlorid
- 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-, ethyl ester, hydrochloride (1:1)
- Umifenovir hydrochloride, 10 mM in DMSO
- ARBIDOL HCL
- Umifenovir hydrochloride
- Umifenovir HCl
- 131707-23-8
- 31707-23-8
- C22H25BrN2O3SHClH2O
- C22H25BrN2O3SHCl
- C22H26BrClN2O3S
- C22H25BrN2O3SClH
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