N-(Tri(hydroxymethyl)methyl)glycin
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- CAS-Nr.
- 5704-04-1
- Bezeichnung:
- N-(Tri(hydroxymethyl)methyl)glycin
- Englisch Name:
- Tricine
- Synonyma:
- TRIS-HCL BUFFER;1389475;TROMETHAMINE HYDROCHLORIDE;Ticine;Tricine buffer, free acid;TRI(HYDROXYMETHYL) AMINO METHANE HYDROCHLORIDE;TRICINE;TRIClNE;n-Tricine-D8;Tricine >99%
- CBNumber:
- CB5853856
- Summenformel:
- C6H13NO5
- Molgewicht:
- 179.17
- MOL-Datei:
- 5704-04-1.mol
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N-(Tri(hydroxymethyl)methyl)glycin Eigenschaften
- Schmelzpunkt:
- 186-188 °C (dec.)
- Siedepunkt:
- 311.69°C (rough estimate)
- Dichte
- 1.05 g/mL at 20 °C
- chüttdichte
- 500kg/m3
- Dampfdruck
- 0.002-0.004Pa at 20-25℃
- Brechungsindex
- 1.4240 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Löslichkeit
- H2O: 4 M at 20 °C, clear, colorless
- Aggregatzustand
- crystalline
- Farbe
- clear colorless (40 % (w/w) in H2O) solution
- Säure-Base-Indikators(pH-Indikatoren)
- 7.4 - 8.8
- Geruch (Odor)
- Odorless
- PH
- 4.0-6.0 (1M in H2O)
- pka
- 8.1(at 25℃)
- Biologische Quelle
- synthetic
- Wasserlöslichkeit
- soluble
- Merck
- 14,9651
- BRN
- 1937804
- Stabilität:
- Stable.
- LogP
- -2.87 at 25℃
- CAS Datenbank
- 5704-04-1(CAS DataBase Reference)
- EPA chemische Informationen
- Glycine, N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]- (5704-04-1)
- Absorption
- ≤0.05 at 280 in H2O at 1M
≤0.1 at 260 in H2O at 1M
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H320 |
Causes eye irritation |
Serious eye damage/eye irritation |
Category 2B |
Warnung |
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P264, P305+P351+P338,P337+P313 |
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| Sicherheit |
| P403 |
An einem gut belüfteten Ort aufbewahren. |
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N-(Tri(hydroxymethyl)methyl)glycin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
White/clear crystalline powder
Verwenden
Good's buffers Tricine is used as an electrophoresis buffer and involved in the separation of low molecular weight proteins and peptides. It operates in the pH range between 7.4 and 8.8. It acts as an effective scavenger of hydroxyl radicals during the study of radiation-induced membrane damage. It is also used in resuspension of cell pellets. It is a zwitterionic amino acid commonly useful in the pH range of 7.4-8.8 and the pKa is 8.05 at 25°C. This buffer is also used as an eluent in asymmetrical flow field-flow fractionation (AFFFF).
Allgemeine Beschreibung
Tricine and its salts are used as biological buffers to control the pH of body fluids
in vitro and
in vivo. It acts as a precursor for polymers, oxazolones (with carboxylic acids), and oxazolidines (with aldehydes). Trizma can serve as an alkalizing agent in treating acidosis of the blood.
Biologische Aktivität
Electrophoresis buffer. Working pH range: 7.4 - 8.8. Commonly used in SDS-PAGE to seperate peptides. Also used in other electrophoresis methods, high performance liquid chromatography and ion exchange chromatopgraphy.
läuterung methode
Crystallise Tricine from EtOH and water. [Good et al. Methods Enzymol 24B 53 1968, McGothlin & Jordan Analyt Lett 9 245 1976, Beilstein 18 III/IV 3454.]
N-(Tri(hydroxymethyl)methyl)glycin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-(Tri(hydroxymethyl)methyl)glycin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 372)Lieferanten
5704-04-1(N-(Tri(hydroxymethyl)methyl)glycin)Verwandte Suche:
- LABOTEST-BB LT00454966
- n-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-glycin
- TRICINE
- TRI(HYDROXYMETHYL) AMINO METHANE HYDROCHLORIDE
- TRIMETHYLOLAMINOMETHANE HYDROCHLORIDE
- TRIClNE
- E-Z 96 SIZE SELECT-IT (1 X 96)
- TRIZMA(R) HYDROCHLORIDE
- TROMETHANE HCL
- TROMETHAMINE HYDROCHLORIDE
- N-[2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]GLYCINE
- MOLE-READY-TRIS
- N-[TRIS(HYDROXYMETHYL)METHYL]GLYCINE
- SPECTRIS(R) HYDROCHLORIDE
- SPECTRIS(TM) HYDROCHLORIDE
- N-(tri(hydroxymethyl)methyl)glycine
- Tricine, Molecular Biology Grade N-Tris(hydroxymethyl)methylglycine, Molecular Biology Grade
- Tricine, ULTROL Grade
- TRICINE, BIOTECHNOLOGY PERFORMANCE CERTI FIED
- TRICINE SIGMAULTRA
- TRICINE 1M SOLUTION, BIOTECHNOLOGY PERFO
- Tricine(N-Tris-(Hydroxymethyl)
- Tricine, 98+%
- Tricine, for biochemistry, 98%
- TRICINE, BIOPERFORMANCE CERTIFIED, C
- Tricine, for biochemistry, 99+%
- n-Tricine-D8
- N-[2-hydroxy-1,1-bis(hydroxyme
- Glycine, N-2-hydroxy-1,1-bis(hydroxymethyl)ethyl-
- N-tris(Hydroxymethyl)methylglycine (TRICINE)
- TRICINE ULTRAPURE
- Tricine >99%
- N-TRIS(HYDROXYMETHYL) METHLGLYCINE extrapure
- tris hydrochloride solution
- Trizma(R) hydrochloride solution
- 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-ylaminoacetic acid
- Carboxymethylaminomethylidynetrimethanol
- 1389475
- OmniPur TRICINE - CAS 1389475 - Calbiochem
- Tricine, ULTROL Grade - CAS 1389475 - Calbiochem
- 2-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}acetic acid
- 2-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]ammonio]acetate
- TRIS(HYDROXYMETHYL)AMINOMETHANE, HCL
- TRIS(HYDROXYMETHYL)METHYLAMINE HYDROCHLORIDE
- TRIS(HYDROXYMETHYL)METHYLAMMONIUM CHLORIDE
- TRIS(HYDROXYMETHYL) METHYLGLYCINE
- TRISMAT(R) HYDROCHLORIDE
- TRISMAT(TM) HYDROCHLORIDE
- TROMETAMOL HYDROCHLORIDE
- N-[1,1-Bis(hydroxymethyl)-2-hydroxyethyl]glycine
- N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]glycine
- Tricine Vetec(TM) reagent grade, >=99%
- Tricine,99+%,for biochemistry
- Tricine,98%,for biochemistry
- Tricine
- Ticine
- Tricine, for biocheMistry, 98% 100GR
- Tricine, for biocheMistry, 98% 250GR
