Dabigatran
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- CAS-Nr.
- 211914-51-1
- Englisch Name:
- Dabigatran
- Synonyma:
- Dabigatran Etexilate Mesilate;BIB-953;CS-1864;BIBR 953;BIBR 953ZW;Dabigatran;Dabiga group;Dabigatran API;Dabigatran base;Dabigatran (Acid)
- CBNumber:
- CB61458206
- Summenformel:
- C25H25N7O3
- Molgewicht:
- 471.51
- MOL-Datei:
- 211914-51-1.mol
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Dabigatran Eigenschaften
- Schmelzpunkt:
- 268-272°C
- Siedepunkt:
- 797.1±70.0 °C(Predicted)
- Dichte
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Löslichkeit
- Aqueous Acid
- Aggregatzustand
- Solid
- pka
- 4.17±0.10(Predicted)
- Farbe
- White to Brown
- InChIKey
- YBSJFWOBGCMAKL-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CCN(C(C1=CC=C2N(C)C(CNC3=CC=C(C(N)=N)C=C3)=NC2=C1)=O)C1=NC=CC=C1
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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Dabigatran Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Tan Solid
Verwenden
BIBR 953 (Dabigatran, Pradaxa) is potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM
Definition
ChEBI: An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-b
ta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism.
Dabigatran Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dabigatran Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 322)Lieferanten
211914-51-1()Verwandte Suche:
- 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Met
- BIBR 953(Dabigatran)
- N-[[2-[[[4-(AMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benzo[d]iMidazol-5-yl]carbonyl]-N-pyridin-2-yl-beta-alanine
- N-[(2-{[(4-carbaMiMidoylphenyl)aMino]Methyl}-1-Methyl-1HbenziMidazol-
5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine
- BIBR 953 (Dabigatran, Pradaxa)
- 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Methyl-benzoiMidazole-5-carbonyl]-pyridin-2-yl-aMino]
- BIB-953
- BIBR 953ZW
- Dabigatran (BIBR 953)
- N- (2-{ (4-carbaMiMidoylphenyl)aMino Methyl}-1-Met
- BIBR 953
- Dabigatran Impurity U
- Dabigatran etexilate-1
- BIBR953;BIBR 953;BIBR-953
- CS-1864
- Dabigatran(BIB-953
- BIBR 953;BIBR 953ZW;BIBR953;BIB-953
- β-Alanine,N-[[2-[[[4-(aMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-
- 3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
- 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid Dabigatran (BIBR 953)
- Dabigatran Impurity b
- Dabigatran (Acid)
- 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic
- Dabigatran3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
- 3-[[2-[[(4-carbamimidoylphenyl)amino]methyl]-1-methyl-benzoimidazole-5-carbonyl]-pyridin-2-yl-amino]propanoic acid
- 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid
- ethyl 3-(2-(((4-(N'-((hexan-2-yloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate
- Dabigatran
- Dabigatran Ester Impurity B
- b-Alanine,N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
- N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine
- Dabigatran USP/EP/BP
- Dabigatran base
- Dabiga group
- N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-ben...
- Dabigatran etexilate impurity189
- Dabigatran etexilate impurity1513
- DabigatranQ: What is
Dabigatran Q: What is the CAS Number of
Dabigatran Q: What is the storage condition of
Dabigatran Q: What are the applications of
Dabigatran
- Dabigatran API
- Dabigatran Standard
- Dabigatran AKSci B955
- 3-[2-[[(4-Carbamimidoylphenyl)amino]methyl]-1-methyl-N-(2-pyridyl)benzimidazole-5-carboxamido]propanoic Acid
- Dabigartan -IP/BP/HIS
- Dabigatran in acetonitrile
- Desethyl Dabigatran Etexilate Impurity D
- D4-Dabigatran hydrochloride
- 3-[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido]propanoic acid
- Dabigatran Etexilate Mesilate
- 211914-51-1
- C25H25N7O3
- Inhibitor
- Intermediates & Fine Chemicals
- Nucleotides
- Pharmaceuticals
- benzimidazol
- Dabigatran impurity
- Aromatics
- Bases & Related Reagents
