cis-4-Hydroxy-L-prolin
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- CAS-Nr.
- 618-27-9
- Bezeichnung:
- cis-4-Hydroxy-L-prolin
- Englisch Name:
- cis-4-Hydroxy-L-proline
- Synonyma:
- (2S,4S)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID;H-CIS-HYP-OH;CIS-4-HYDROXYPROLINE;CIS-HYP-OH;CIS-HYDROXYPROLINE;cis-Hydroxy-L-proline;(4S)-4-hydroxypyrrolidine-2-carboxylic acid;CHYP;cis L;cis-L-Hyp-OH
- CBNumber:
- CB6158895
- Summenformel:
- C5H9NO3
- Molgewicht:
- 131.13
- MOL-Datei:
- 618-27-9.mol
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cis-4-Hydroxy-L-prolin Eigenschaften
- Schmelzpunkt:
- 257 °C (dec.) (lit.)
- alpha
- -59 º (c=2, H2O)
- Siedepunkt:
- 242.42°C (rough estimate)
- Dichte
- 1.3121 (rough estimate)
- Brechungsindex
- -59 ° (C=2, H2O)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Löslichkeit
- soluble
- Aggregatzustand
- Powder
- pka
- 2.14±0.40(Predicted)
- Farbe
- White to beige
- Wasserlöslichkeit
- soluble
- Merck
- 14,4840
- BRN
- 81440
- Major Application
- peptide synthesis
- InChI
- 1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
- InChIKey
- PMMYEEVYMWASQN-IMJSIDKUSA-N
- SMILES
- O[C@@H]1CN[C@@H](C1)C(O)=O
- CAS Datenbank
- 618-27-9(CAS DataBase Reference)
- EPA chemische Informationen
- L-Proline, 4-hydroxy-, (4S)- (618-27-9)
cis-4-Hydroxy-L-prolin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getränkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White to beige powder
Verwenden
cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.
Definition
ChEBI: L-Proline in which a hydrogen at the 4-position of the pyrrolidine ring is substituted by a hydroxy group (S-configuration).
cis-4-Hydroxy-L-prolin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
cis-4-Hydroxy-L-prolin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 360)Lieferanten
618-27-9(cis-4-Hydroxy-L-prolin)Verwandte Suche:
- L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLIC ACID
- L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLLIC ACID
- L-ALLO-HYDROXYPROLINE
- CIS-4-HYDROXY-L-PROLINE
- CIS-L-4-HYDROXYPROLINE
- CHYP
- HYDROXY-L-PROLINE [ALLO]
- H-PRO(CIS-4-OH)-OH
- H-L-CIS-HYP-OH
- cis-4-Hydroxy-L-proline, 97.0%(T)
- cis-L-4-Hydroxyproline≥ 99% (NMR)
- cis-L-Hyp-OH
- cis-4-Hydroxy-L-proline Hydrochloride,99%e.e.
- cis-4-Hydroxy-L-proline Vetec(TM) reagent grade, 98%
- (4S)-4-hydroxypyrrolidine-2-carboxylic acid
- CIS-4-HYDROXY-L-PROLINE HYDROLORIDE
- (2S,4S)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid 97%
- L-CIS-4-HYDROXYPROLINE
- L-CIS-HYDROXYPROLINE
- (2S,4S)-(-)-4-HYDROXY-2-PYRROLINECARBOXYLIC ACID
- ALLO-4-HYDROXY-L-PROLINE
- cis-4-L-Hydroxyproline
- (2S,4S)-(-)-4-Hydroxypyrrolidin-2-ylcarboxylic acid
- CIS-4-HYDROXY-L-PROLINE NATURAL ISOMER
- -ALLO-HYDROXYPROLINE
- 4-CIS-HYDROXYPROLINE
- L-CIS-HYDROXYPROLINE, (2S,4S)-(-)-4-HYDROXY-2-PYRROLINECARBOXYLIC ACID
- (2S,4S)-4-HYDROXY-L-PROLINE
- (2S)-4α-Hydroxy-2α-pyrrolidinecarboxylic acid
- (4S)-4-Hydroxy-L-proline
- cis-Hydroxy-L-proline
- cis-4-Hydroxy-L-proline,99%
- Cis-4-Hydroxy-L-proline methyl ester
- (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid hydrochloride
- Cis-4-hydroxy-L-proline Hyadrochloride
- (2S,4S)-4-Hydroxyproline
- (S)-Allo-hydroxyproline
- cis-4-Hydroxy-L-proline collagen synthesis inhibitor
- cis L
- cis-4-Hydroxy-L-proline>
- cis-4-Hydroxy-L
- L-Proline, 4-hydroxy-, (4S)-
- cis-4-Hydroxy-L-proline USP/EP/BP
- proline,collagen,Inhibitor,cis4HydroxyLproline,tumor,cis 4 Hydroxy L proline,inhibit,Endogenous Metabolite,fibroblast
- Coclaurine Impurity 4
- (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid/cis-4-Hydroxy-L-proline
- cis-4-Hydroxy-L-proline
- (2S,4S)-cis-4-hydroxy-L-proline
- (2S,4S)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
- CIS-HYP-OH
- CIS-HYDROXYPROLINE
- CIS-4-HYDROXYPROLINE
- H-CIS-HYP-OH
- 618-27-9
- 618-21-7
- Specialty Synthesis
- Proline Derivatives
- Peptide Synthesis
