Adenosin-5'-(trihydrogen-diphosphat), 2'-(Dihydrogen-phosphat), 5'-5'-Ester mit 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium-hydroxid, inneres Salz, Mononatriumsalz Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36:Reizt die Augen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White to slightly yellowish powder
Verwenden
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions.
β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt Hydrate is a substrate NADP which plays a role in a variety of metabolic processes.
Biosynthese
A process for preparing NADP sodium salt comprising performing phosphorylation using a polyphosphoric acid or a salt thereof and nicotinamide adenine dinucleotide (NAD+) as substrates in the presence of a polyphosphate-dependent NAD+ kinase from a Mycobacterium, wherein the reaction solution contains 0.1-15% by weight of the polyphosphoric acid or a salt thereof, and 5-150 mM of a divalent metal ion.
Biologische Funktion
NADP sodium salt is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. It plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes.
Biochem/physiol Actions
Electron acceptor
Mechanism of action
NADP sodium salt exerts its effect by competitively inhibiting nucleotide metabolism through the suppression of enzymes like nucleoside diphosphate kinase (NDPK) and adenosine kinase (ADK). Additionally, it serves as a substrate for enzymes like DNA polymerases and RNA polymerases, enabling the integration of NADP monosodium salt into nucleic acids during replication and transcription.
Adenosin-5'-(trihydrogen-diphosphat), 2'-(Dihydrogen-phosphat), 5'-5'-Ester mit 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium-hydroxid, inneres Salz, Mononatriumsalz Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
