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Difamilast

Difamilast Struktur
937782-05-3
CAS-Nr.
937782-05-3
Englisch Name:
Difamilast
Synonyma:
OPA15406);Difamilast;Difa Misite;Difamilast (OPA-15406;Difamilast 937782-05-3;Difamilast, 10 mM in DMSO;N-((2-(4-(difluoromethoxy)-3-isopropoxyphenyl)oxazol-4-yl)methyl)-2-ethoxybenzamide;N-[[2-[4-(Difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxybenzamide;N-[[2-[4-(difluoromethoxy)-3-propan-2-yloxyphenyl]-1,3-oxazol-4-yl]methyl]-2-ethoxybenzamide;Benzamide, N-[[2-[4-(difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxy-
CBNumber:
CB64694667
Summenformel:
C23H24F2N2O5
Molgewicht:
446.44
MOL-Datei:
937782-05-3.mol
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Difamilast Eigenschaften

Dichte
1.223±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
DMSO : 100 mg/mL (223.99 mM; Need ultrasonic)
pka
13.12±0.46(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white
InChI
InChI=1S/C23H24F2N2O5/c1-4-29-18-8-6-5-7-17(18)21(28)26-12-16-13-30-22(27-16)15-9-10-19(32-23(24)25)20(11-15)31-14(2)3/h5-11,13-14,23H,4,12H2,1-3H3,(H,26,28)
InChIKey
VFBILHPIHUPBPZ-UHFFFAOYSA-N
SMILES
C(NCC1=COC(C2=CC=C(OC(F)F)C(OC(C)C)=C2)=N1)(=O)C1=CC=CC=C1OCC

Sicherheit

Difamilast Chemische Eigenschaften,Einsatz,Produktion Methoden

Trademarks

Moizerto

Biologische Aktivität

Difamilast is a novel atopic dermatitis drug candidate discovered by Otsuka that has phosphodiesterase 4 (PDE4) inhibitory activity. 

Difamilast Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Difamilast Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 45)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hefei TianRui Pharmaceutical Chemical Co., Ltd.
+86-0551-68665055 +86-+86-18616906106
 sales@trywchem.com China 149 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354
 marketing@targetmol.com United States 32433 58
Jiangxi Huihe Chemical Co., Ltd. 		+86-19189228086 +8618858568638
 wuzhouding@huihecrop.com China 886 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Chongqing jooe co., ltd 		+86-19923400328 +86-15223382610
 info@jooe.com China 5617 58
Bayee Biotech (Anqing) Co., Ltd. 0556-5032306 18917961636
 wtx@bayeebio.com China 231 61
Hefei TianRui Pharmaceutical Chemistry Co., Ltd. 0551-68933033 13956024211
 trchem@163.com China 92 58
Shanghai Yatan Pharmaceutical Research and Development Co. LTD 58003085 13524705178
 sunk@neutanpharma.com China 182 58
Nanjing Chemlin Chemical Co., Ltd 025-83697070
info@chemlin.com.cn China 14827 64
Zhengzhou HSH Science & Technology Co., Ltd. 0371-55932928 18937192232
 1282296214@qq.com China 498 55
  • Difamilast 937782-05-3
  • Difamilast (OPA-15406
  • OPA15406)
  • Benzamide, N-[[2-[4-(difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxy-
  • N-[[2-[4-(difluoromethoxy)-3-propan-2-yloxyphenyl]-1,3-oxazol-4-yl]methyl]-2-ethoxybenzamide
  • Difamilast,PDE4,OPA 15406,Inhibitor,atopic,phosphodiesterase-4,OPA15406,Phosphodiesterase (PDE),OPA-15406,dermatitis,subtype,inhibit
  • Difamilast
  • N-((2-(4-(difluoromethoxy)-3-isopropoxyphenyl)oxazol-4-yl)methyl)-2-ethoxybenzamide
  • Difamilast, 10 mM in DMSO
  • N-[[2-[4-(Difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxybenzamide
  • Difa Misite
  • 937782-05-3
  • API
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