1,3-Dimethylpentylamin

1,3-Dimethylamylamine Struktur
105-41-9
CAS-Nr.
105-41-9
Bezeichnung:
1,3-Dimethylpentylamin
Englisch Name:
1,3-Dimethylamylamine
Synonyma:
1,3-Dimethylamylamine;Methylhexanamine;DiMethylaMylaMine;Methylhexaneamine;4-Methylhexan-2-amine;2-Hexanamine, 4-methyl-;4-Methyl-2-hexanamine;1,3-Dimethylpentylamine;2-AMINO-4-METHYLHEXANE;1,3-diMethylaMylaMine HCl
CBNumber:
CB8211488
Summenformel:
C7H17N
Molgewicht:
115.22
MOL-Datei:
105-41-9.mol

1,3-Dimethylpentylamin Eigenschaften

Schmelzpunkt:
-19°C (estimate)
Siedepunkt:
bp760 130-135°
Dichte
0.7620-0.7655
Brechungsindex
n20/D1.417-1.419
Flammpunkt:
43℃
pka
pKa 10.54(H2O,t =24±1,I=0.002) (Uncertain)
Henry's Law Constant
2.3×10-1 mol/(m3Pa) at 25℃, HSDB (2015)
InChI
InChI=1S/C7H17N/c1-4-6(2)5-7(3)8/h6-7H,4-5,8H2,1-3H3
InChIKey
YAHRDLICUYEDAU-UHFFFAOYSA-N
SMILES
CC(N)CC(C)CC
CAS Datenbank
105-41-9(CAS DataBase Reference)
NIST chemische Informationen
2-Hexanamine, 4-methyl-(105-41-9)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher C
R-Sätze: 10-22-34
S-Sätze: 26-36/37/39-45
RIDADR  UN 2734PSN1 3(8) / PGII
WGK Germany  3
RTECS-Nr. SC0800000
Giftige Stoffe Daten 105-41-9(Hazardous Substances Data)
Bildanzeige (GHS) Flame (GHS02)Corrosion (GHS05)Exclamation Mark (GHS07)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H226 Flüssigkeit und Dampf entzündbar. Entzündbare Flüssigkeiten Kategorie 3 Warnung
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H314 Verursacht schwere Verätzungen der Haut und schwere Augenschäden. Ätzwirkung auf die Haut Kategorie 1B Achtung P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P210 Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P233 Behälter dicht verschlossen halten.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P303+P361+P353 BEI BERÜHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen oder duschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

1,3-Dimethylpentylamin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

1,3-dimethylamylamine or methylexaneamine (DMAA) is a synthetic pharmaceutical patented in the 1940s as a nasal decongestant which can be used as a recreational stimulant. Alleged to occur in nature,DMAA has become a widely used ingredient in sports food supplements, despite its status as a doping agent and concerns over its safety. The most popular brands containing DMAA include Jack3d and OxyElite Pro, both marketed by USP Labs and both detained by the FDA in July 2013 (however, some can still be found on Amazon and other online retail stores).

Chemische Eigenschaften

White or almost white powder

Verwenden

DMAA (1,3-dimethylamylamine) is an amphetamine derivative that has been widely used in sports supplements sold in the United States. Also known as methylhexanamine or geranium extract, DMAA is often touted as a "natural" stimulant, with many claimed functional uses including a body-building aid, an athletic performance enhancer, and a weight-loss aid. Although DMAA at one time was approved as a drug for nasal decongestion, no medical use of DMAA is recognized today. FDA is not aware of any reliable science indicating that DMAA exists naturally in plants.

Application

1,3-Dimethylamylamine (1,3-DMAA) is a neural stimulant with a structure similar to ephedrine and adrenaline that has been used as a pre-workout stimulant. It is useful in compositions, for example as dietary supplements, and for appetite suppression. Methylhexaneamine is a botanical ingredient in dietary supplements. Methylhexaneamine and caffeine has been combined in attempts to improve exercise performance and related variables.

Pharmakokinetik

Oral Clearance (CL) values (CL/F; F represents oral bioavailability) were found to be relatively low (20±5.0 L/hr), whereas oral Volume of distribution (V/F) was relatively high (236±38.0 L). A 25 mg single oral dose resulted in a maximum plasma concentration (Cmax) of 76.5 ng/mL, which occurred approximately 4 hours post-ingestion. Cmaxvalues were approximately 15-30 times lower than those reported in case studies linking 1,3-Dimethylamylamine (DMAA) intake with severe adverse events, suggesting that the reported adverse events were associated with a DMAA intake much higher than the 25 mg dose in our study [9,10]. Additionally, the potential impact of drug-drug interactions should be considered when interpreting DMAA adverse event reports. Because DMAA PK data suggest that a significant fraction of an orally administered DMAA dose is metabolized, concomitant administration of common ingredients that are also metabolized (e.g., caffeine), may lead to exaggerated DMAA concentrations by inhibiting DMAA clearance.

Nebenwirkungen

Taking 1,3-Dimethylamylamine (DMAA) can raise blood pressure and lead to cardiovascular problems ranging from shortness of breath and tightening in the chest to heart attack. It  may also cause stroke, a condition called lactic acidosis, heart attack, liver injury, and death.

1,3-Dimethylpentylamin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1,3-Dimethylpentylamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 142)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
NingBo Sialon Chem Co., Ltd. 0574-28809768 18658497215
sales@newsialon.com China 40 58
INTATRADE GmbH +49 3493/605464
sales@intatrade.de Germany 3563 66
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960
info@chemlin.com.cn China 16306 64
Syntechem Co.,Ltd
info@syntechem.com China 12973 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771
sales@heowns.com China 14412 57
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 452520369
sales@maya-r.com China 11693 57
Tongchuang Pharma(Suzhou). Co., Ltd. 0512-63263366 18912765016
tongtf110@sina.com China 984 62
T&W GROUP 021-61551611 13296011611
contact@trustwe.com China 9884 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611
China 9874 58
Candia Thamtech Company Limited 0371-86615086 18203638366 0371-86159066 13526786601
China 2011 60

105-41-9(1,3-Dimethylpentylamin)Verwandte Suche:


  • Fouramin
  • Metexaminum
  • Methexaminum
  • Methylhexamine
  • GERANAMINE
  • 2-AMINO-4-METHYLHEXANE HYDROCHLORIDE 98%
  • Inchi=1/C7H17N/C1-4-6(2)5-7(3)8/H6-7H,4-5,8H2,1-3h
  • 1,3-DiMethylpentylaMine2-AMino-4-Methylhexane
  • 1,3-Dimethylpentanamine
  • 1,3-Dimethylamylamine
  • 1,3-Dimethylamylamineforthane
  • 1,3-dimethyl-pentylamin
  • 4-Methyl-2-hexanamine
  • 4-Methyl-2-hexylamine
  • Forthan
  • Forthane
  • Pentylamine, 1,3-dimethyl-
  • RARECHEM AN KC 0206
  • 4-METHYL-2-AMINO HEXANE
  • 2-amino-4-methylhexanehcl
  • Methylhexaneamine(Mixture of Diastereomers) (Discontinued, see D476600)
  • 1,3-Dimethylpentylamine/Methylhexanamine/ DMAA powder
  • 1,3-Dimethylpentylamine Basic information
  • 1,3-dimethylamylamin HCL
  • Methylhexanamine (1,3-Dimethylamylamine, DMAA)
  • 1,3-dimethyl-pentylamine HCl salt
  • 1,3-dimethylbenzoyl chloride
  • 1,3-Dimethylpentylamine,98.5%
  • 4-methylhexan-2-amine(methylhexaneamine)
  • 1,3-dimethylamylamine HCl / DMAA
  • DMAA,1,3-Dimethylamylamine
  • 1,3-Dimethylamylamine 100 μg/mL in Acetonitrile
  • 2-AMINO-4-METHYLHEXANE
  • 1,3-diMethylaMylaMine HCl
  • 1,3-Dimethylpentylamine
  • 2-Hexanamine, 4-methyl-
  • 4-Methylhexan-2-amine
  • DiMethylaMylaMine
  • Methylhexaneamine
  • Methylhexanamine
  • 105-41-9
  • 105419
  • intermediates
  • Aliphatics
  • Amines
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Small molecule
  • 105-41-9
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