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Tocoretinate

Tocoretinate Struktur
40516-48-1
CAS-Nr.
40516-48-1
Englisch Name:
Tocoretinate
Synonyma:
tretinoin tocoferil;N 021;L 300;Olcenon;TOCORETINATE;dl-a-Tocopheryl Retinoate;dl-α-Tocopheryl Retinoate;VITAMIN E VITAMIN A ACID ESTER;Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, (±)-;Retinoic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+-)-
CBNumber:
CB8700933
Summenformel:
C49H76O3
Molgewicht:
713.13
MOL-Datei:
40516-48-1.mol
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Tocoretinate Eigenschaften

Siedepunkt:
761.3±60.0 °C(Predicted)
Dichte
0.959±0.06 g/cm3(Predicted)
CAS Datenbank
40516-48-1(CAS DataBase Reference)

Sicherheit

Toxizität LD50 in mice (mg/kg): >1000 i.v.; >2000 orally (Fukawa, 1975)

Tocoretinate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tretinoin tocoferil, the a-tocopherol ester of all-trans-retinoic acid, was launched for the treatment of bedsores and skin ulcers such as burn, leg, and diabetic ulcers. It is also an orally active agent for gastric ulcer treatment. Tretinoin tocoferil represents a new class of antiulcer drugs which act by directly promoting tissue repair, distinguished from common drugs that exert an indirect function by suppression of acid-secretion and mucosa protection. The mode of its action has been proposed to relate to its ability to stimulate DNA synthesis of growth-arrested human skin fibroblasts by promoting expression of the epidermal growth factor receptor.

Verwenden

dl-α-Tocopheryl Retinoate is an α-tocopherol ester of all-trans retinoic acid (R250200) and is safely used in the treatment of skin ulcer. dl-α-Tocopheryl Retinoate inhibited proliferation of human promyelocytic leukemia HL-60 cells and induced granulocytic differentiation of the cells, but to a lesser extent than did retinoic acid.

Tocoretinate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Tocoretinate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 47)Lieferanten
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CONIER CHEM AND PHARMA LIMITED
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SIMAGCHEM CORP 		+86-5922680277 +86-13806087780
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BOC Sciences 		16314854226; +8616314854226
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Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 17705817739
 info@dycnchem.com China 52693 58
GIHI CHEMICALS CO.,LIMITED 		+86-571-86217390; +8618058761490
 info@gihichemicals.com China 49859 58
Mainchem Co., Ltd. +86-0592-6210733
sale@mainchem.com China 32288 55
Wuhan Wei Shunda Technology Development Co., Ltd. 86-027-88774375
mwmwhot@163.com China 233 65
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2110 70

40516-48-1()Verwandte Suche:

Centchroman Vitamin-A-säure Propyleneglycol alginate Tetrahydropyran Isobuttersure, Monoester mit 2,2,4-Trimethylpentan-1,3-diol [3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]hydrogensuccinat Ethylvanillat α-Tocopherol Vitamin A 3-Pentadecylphenol α-Tocopherylacetat 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol [2R*(4R*,8R*)]-(±)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ylacetat [2R[2R*(4R*,8R*)]]-3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol 3,4-Dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol 4-Hydroxy-2,3,6-trimethylphenylacetat
  • TOCORETINATE
  • 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-yl-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
  • VITAMIN E VITAMIN A ACID ESTER
  • L 300
  • N 021
  • Olcenon
  • Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, rel- (9CI)
  • Retinoic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+-)-
  • Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, (±)-
  • dl-α-Tocopheryl Retinoate
  • dl-a-Tocopheryl Retinoate
  • tretinoin tocoferil
  • 40516-48-1
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