2-Brom-1-(4-hydroxyphenyl)ethan-1-on
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- CAS-Nr.
- 2491-38-5
- Bezeichnung:
- 2-Brom-1-(4-hydroxyphenyl)ethan-1-on
- Englisch Name:
- 2-Bromo-4'-hydroxyacetophenone
- Synonyma:
- 2-bromo-1-(4-hydroxyphenyl)ethan-1-one;BHAP;BUSAN90;BUSAN1130;Butrol 1130;PTP INHIBITOR I;SHP-1 Inhibitor II;4-HYDROXYPHENACYL BR;4-(Bromoacetyl)phenol;(+)-alpha-isolupanine
- CBNumber:
- CB9306895
- Summenformel:
- C8H7BrO2
- Molgewicht:
- 215.04
- MOL-Datei:
- 2491-38-5.mol
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2-Brom-1-(4-hydroxyphenyl)ethan-1-on Eigenschaften
- Schmelzpunkt:
- 123-126°C
- Siedepunkt:
- 338.7±17.0 °C(Predicted)
- Dichte
- 1.622±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- White powder
- pka
- 7.69±0.15(Predicted)
- Farbe
- White to Light Beige
- Sensitive
- Lachrymatory
- BRN
- 1865388
- Stabilität:
- Hygroscopic
- InChI
- InChI=1S/C8H7BrO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,10H,5H2
- InChIKey
- LJYOFQHKEWTQRH-UHFFFAOYSA-N
- SMILES
- C(=O)(C1=CC=C(O)C=C1)CBr
- CAS Datenbank
- 2491-38-5(CAS DataBase Reference)
- EPA chemische Informationen
- 2-Bromo-4-hydroxyacetophenone (2491-38-5)
2-Brom-1-(4-hydroxyphenyl)ethan-1-on Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with a K
i value of 43 μM and PTP1B with a K
i value of 42 μM. SHP-1 and PTP1B both have known roles in regulating insulin signaling as well as myeloid and lymphoid cell differentiation, making inhibitors of these phosphatases of interest in diabetes, cancer, allergy, and inflammation research.
Chemische Eigenschaften
Pale Beige Solid
Verwenden
A covalent inhibitor of protein tyrosine phosphatases (PTPs)
synthetische
Also obtained by reaction of pyridinium hydrobromide perbromide with 4-hydroxyacetophenone in THF at r.t. for 3 h.
2-Brom-1-(4-hydroxyphenyl)ethan-1-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Brom-1-(4-hydroxyphenyl)ethan-1-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 340)Lieferanten
2491-38-5(2-Brom-1-(4-hydroxyphenyl)ethan-1-on)Verwandte Suche:
- PTP INHIBITOR I
- PROTEIN TYROSINE PHOSPHATASE INHIBITOR I
- ALPHA-BROMO-4-HYDROXYACETOPHENONE
- 4-HYDROXYPHENACYL BR
- 4-HYDROXYPHENACYL BROMIDE
- 2-BROMO-1-(4-HYDROXY-PHENYL)-ETHANONE
- 2'-BROMO-4'-HYDROXYACETOPHENONE
- 4-Hydroxy α-Bromoacetophenone
- 4-HYDROXY A-BROMOACETOPHENONE
- Ethanone, 2-bromo-1-(4-hydroxyphenyl)-
- A-BROMO-4-HYDROXY ACETOPHENONE
- 1-(4-hydroxyphenyl)-2-bromoethanone
- BROMOHYDROXYACETOPHENONE
- BHAP
- BUSAN1130
- BUSAN90
- 2-Brom-1-(4-hydroxyphenyl)ethan-1-on
- α-Bromo-4-hydroxyacetophenone
- 4-Hydroxy-alpha-bromoacetophenone
- 2-Bromo-4-Hydroxyacetophenone98%
- Alpha broMine generation of hydroxy acetophenone
- α-broMo p-hydroxyacetophenone
- 4-(Bromoacetyl)phenol
- p-Hydroxy α-Bromoacetophenone
- 2-Bromo-4'-hydroxyacetophenone, 2-Bromo-1-(4-hydroxyphenyl)ethan-1-one
- Aipha-BroMo-4-hydroxyacetophenone
- Butrol 1130
- p-Hydroxyphenacyl BroMide
- 4-Hydroxyphenacyl bromide 97%
- PTP Inhibitor I - CAS 2491-38-5 - Calbiochem
- 2-Bromo-4'-hydroxyacetophenone >
- SHP-1 Inhibitor II
- 2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I)
- 2-Bromo-4'-hydroxyacetophenone
- Cyclohexane Impurity 5
- Isavuconazole Impurity N16
- 2-Bromo-4''-hydroxyacetophenone
- 2-Bromo-4''-hydroxyacetophenone, 10 mM in DMSO
- (+)-alpha-isolupanine
- 2-bromo-1-(4-hydroxyphenyl)ethan-1-one
- 2491-38-5
- Aromatics
- Inhibitors
- Aromatic Acetophenones & Derivatives (substituted)
