Alectinib Intermediates

Alectinib Intermediates Struktur
1256584-77-6
CAS-Nr.
1256584-77-6
Englisch Name:
Alectinib Intermediates
Synonyma:
Alectinib Impurity 7;Aletinib Impurity 8(hydrochloride);tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate;tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate HCl;tert-Butyl 6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate Hydrochloride;tert-butyl 6-cyano-2-(2-{4-ethyl-3-[4-(morpholin-4-yl)piperidin-1-yl]phenyl}propan-2-yl)-1H-indole-3-carboxylate hydrochloride (1:1);6-Cyano-2-[1-[4-ethyl-3-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester hydrochloride;6-Cyano-2-[1-[4-ethyl-3-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester hydrochloride (1:1)
CBNumber:
CB93151786
Summenformel:
C34H45ClN4O3
Molgewicht:
593.21
MOL-Datei:
1256584-77-6.mol

Alectinib Intermediates Eigenschaften

InChIKey
VDZPTVLTFFGRJW-UHFFFAOYSA-N
SMILES
C(C1C2=CC=C(C#N)C=C2NC=1C(C1C=CC(CC)=C(N2CCC(N3CCOCC3)CC2)C=1)(C)C)(=O)OC(C)(C)C.Cl

Sicherheit

Alectinib Intermediates Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

tert-Butyl 6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate Hydrochloride is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.

Alectinib Intermediates Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Alectinib Intermediates Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate
  • Alectinib Impurity 7
  • tert-Butyl 6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate Hydrochloride
  • 6-Cyano-2-[1-[4-ethyl-3-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester hydrochloride
  • tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate HCl
  • Aletinib Impurity 8(hydrochloride)
  • tert-butyl 6-cyano-2-(2-{4-ethyl-3-[4-(morpholin-4-yl)piperidin-1-yl]phenyl}propan-2-yl)-1H-indole-3-carboxylate hydrochloride (1:1)
  • 6-Cyano-2-[1-[4-ethyl-3-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester hydrochloride (1:1)
  • 1256584-77-6
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