β-Chlorpropiophenon
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- CAS-Nr.
- 936-59-4
- Bezeichnung:
- β-Chlorpropiophenon
- Englisch Name:
- 3-Chloropropiophenone
- Synonyma:
- 3-chloro-1-phenylpropan-1-one;3-CHLORO-1-PHENYL-1-PROPANONE;1-Propanone, 3-chloro-1-phenyl-;NSC 37238;NSC 227202;JACS-936-59-4;oropropiophenone;β-Chlorpropiophenon;á-chloropropiophenone;B-CHLOROPROPIOPHENONE
- CBNumber:
- CB9332104
- Summenformel:
- C9H9ClO
- Molgewicht:
- 168.62
- MOL-Datei:
- 936-59-4.mol
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β-Chlorpropiophenon Eigenschaften
- Schmelzpunkt:
- 48-50 °C(lit.)
- Siedepunkt:
- 113-115 °C4 mm Hg(lit.)
- Dichte
- 1.1115 (rough estimate)
- Brechungsindex
- 1.5350 (estimate)
- Flammpunkt:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- Off-White to Pale Yellow
- Wasserlöslichkeit
- Insoluble
- BRN
- 2043580
- Stabilität:
- Stable. Incompatible with strong bases, strong oxidizing agents.
- CAS Datenbank
- 936-59-4(CAS DataBase Reference)
- NIST chemische Informationen
- 1-Propanone, 3-chloro-1-phenyl-(936-59-4)
- EPA chemische Informationen
- 1-Propanone, 3-chloro-1-phenyl- (936-59-4)
β-Chlorpropiophenon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
3-Chloropropiophenone is a chiral compound that is used as an antidepressant drug. It was first synthesized in the 1950s and has been studied extensively for its pharmacological effects. It is a racemic mixture of two enantiomers, one of which is active and the other inactive. The active enantiomer binds to serotonin receptors and inhibits the reuptake of serotonin, which leads to an increase in serotonin levels. The inactive enantiomer does not bind to serotonin receptors and does not inhibit the reuptake of serotonin. 3-Chloropropiophenone has been shown to be effective when administered at an optimum concentration of 5 milligrams per kilogram body weight.
Chemische Eigenschaften
faintly yellow to tan crystalline powder
Verwenden
3-Chloropropiophenone is an Impurity of Fluoxetine (F597100).
Synthese
Adding 3' -chlorobenzene acetone and levorotatory prolinol into 95% ethanol and stirring; cooling after the reaction liquid is wholly dissolved; adding potassium borohydride into the reaction solution in batches, and preserving heat after adding; heating the reaction solution for reflux reaction, and concentrating the reaction solution under reduced pressure; adding n-hexane into the reaction solution, heating, and adding active carbon for heat preservation and decoloration; filtering the reaction solution, leaching a filter cake by using normal hexane, and collecting filtrate; crystallizing and filtering the filtrate, leaching the filter cake once with n-hexane, and drying in vacuum to obtain 3-Chloropropiophenone.
β-Chlorpropiophenon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
β-Chlorpropiophenon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 486)Lieferanten
936-59-4(β-Chlorpropiophenon)Verwandte Suche:
- 3-CHLORO-1-PHENYL-1-PROPANONE
- 3-CHLORO-1-OXO-1-PHENYLPROPANE
- B-CHLOROPROPIOPHENONE
- BETA-CHLOROPROPIOPHENONE
- 3-Chloropropiophenone98%
- Chloropropiophenone, 98+%
- beta-Chloropropiophenone,98+%
- 3-Chloropropiophenone, tech., 90%
- á-chloropropiophenone
- SS-CHLORO -PHENYL-1-PROPANONE
- 3-chloro-1-phenylpropan-1-one
- 3-Chloropropiophenone 90%
- 1-Propanone, 3-chloro-1-phenyl-
- 3-Chloropropiophenone, 90%, tech.
- -Chloro-Phenyl-1-Propanone
- (3-Chloropropionyl)benzene
- 1-Phenyl-3-chloro-1-propanone
- 2-Chloro-1-benzoylethane
- 3-Chloropropiophenone,95%
- 1-Propanone,3-chloropropiophenone
- 3-CHLOROPROPIOPHENONE pure
- β-Chloropropiophenone, 3-Chloro-1-phenyl-1-propanone
- NSC 227202
- NSC 37238
- β-Chloroethyl phenyl ketone
- 3-Chloropropiophenone
- 2-Chloroethyl phenyl ketone
- 3-chloro-1-phenyl-1-propanon
- 3-Chloropropanophenone
- beta-Chloroethyl phenyl ketone
- omega-Chloropropiophenone
- Propiophenone, 3-chloro-
- 3-Chloropropiophenone, technical grade
- 3-CHLOROPROPIOPHENONE 99+%
- oropropiophenone
- JACS-936-59-4
- 3-Chloropropiophenone >
- Bupropion 3-CPP Impurity
- β-Chlorpropiophenon
- Bupropion Des-t-tbutylamine Impurity (3’-Chloropropiophenone)
- TIANFUCHEM--936-59-4---3-Chloropropiophenone
- 3-Chloro-1-Phenyl Propanone pure, 98%
- 3-Chloropropiophenone / β-Chloropropiophenone
- Meta Chloro Propiophenone
(MCPP)
- B-Chloropropiophenone
3-Chloropropiophenone
- β-chloropropiophenone
- 3-Chloropropiophenone, 10 mM in DMSO
- 936-59-4
- ClCH2CH2COC6H5
- C9H9CIO
- KETONE
- Building Blocks
- C9
- Carbonyl Compounds
- Ketones
- Organic Building Blocks
- Building Blocks
- C9
