Epitinib (succinate)
- CAS No.
- 2252334-12-4
- Chemical Name:
- Epitinib (succinate)
- Synonyms
- Epitinib (succinate)
- CBNumber:
- CB010222443
- Molecular Formula:
- C28H32N6O6
- Molecular Weight:
- 548.6
- MDL Number:
- MOL File:
- 2252334-12-4.mol
| storage temp. | Store at -20°C |
|---|---|
| form | Solid |
| color | White to light yellow |
| FDA UNII | 2138WW3F3R |
Epitinib (succinate) Chemical Properties,Uses,Production
Uses
Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer[1][2]. Epitinib (succinate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References
[1] Zhou et al. The safety profile of a selective EGFR TKI epitinib (HMPL-813) in patients with advanced solid tumors and preliminary clinical efficacy in EGFRm+ NSCLC patients with brain metastasis. Journal of Clinical Oncology 2016 34:15_suppl, e20502-e20502
[2] Zhou et al. Phase I study of the safety and pharmacokinetics of epitinib, an oral EGFR tyrosine kinase inhibitor, in patients with advanced solid tumors. Journal of Clinical Oncology 2013 31:15_suppl, e19042-e19042
Epitinib (succinate) Preparation Products And Raw materials
Raw materials
Preparation Products
Epitinib (succinate) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32432 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4808 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29545 | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 6710 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
| Guangzhou Junze Biotechnology Co., Ltd. | 17688489295 | CHINA | 188 | 58 |
View Lastest Price from Epitinib (succinate) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-22 | Epitinib succinate
2252334-12-4
|
US $69.00-173.00 / mg | 99.79% | 10g | TargetMol Chemicals Inc. |
-
- Epitinib succinate
2252334-12-4
- US $69.00-173.00 / mg
- 99.79%
- TargetMol Chemicals Inc.
