Bapotulimab
- CAS No.
- 2359413-58-2
- Chemical Name:
- Bapotulimab
- Synonyms
- Bapotulimab;Bapotulimab (anti-ILDR2);Research Grade Bapotulimab;Research Grade Bapotulimab (DHB96301)
- CBNumber:
- CB010617007
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | I92BM16NTD |
Bapotulimab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 591690 | Bapotulimab ≥95% | 2359413-58-2 | 100ug | $829 | 2026-06-03 | Buy |
| ChemScene | CS-0627732 | Bapotulimab 99.00% | 2359413-58-2 | 1mg | $498 | 2026-06-04 | Buy |
| ChemScene | CS-0627732 | Bapotulimab 99.00% | 2359413-58-2 | 5mg | $1062 | 2026-06-04 | Buy |
| ChemScene | CS-0627732 | Bapotulimab 99.00% | 2359413-58-2 | 10mg | $1517 | 2026-06-04 | Buy |
| aablocks | AA029VJH | Bapotulimab ≥95%(SDS-PAGE&SEC-HPLC) | 2359413-58-2 | 1mg | $732 | 2026-06-02 | Buy |
Bapotulimab Chemical Properties, Uses, Production
Uses
Bapotulimab (BAY-1905254) is a fully human IgG2 antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2). Bapotulimab has antitumor and immunosuppressive effects[1].
in vivo
Bapotulimab (BAY-1905254; 10 mg/kg; i.p.; on days 1 and 4) shows significantly increased antigen-specific T-cell proliferation and cytotoxicity[1].
| Animal Model: | 8- to 12-week-old CD45.1-expressing C57BL/6 wild-type mice injected with OT-I transgenic T cells[1] |
| Dosage: | 10 mg/kg |
| Administration: | i.p.; on days 1 and 4 |
| Result: | Showed significantly increased antigen-specific T-cell proliferation and cytotoxicity. |
References
[1] Julia Huetter, et al. Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2). Cancer Immunol Res. 2020 Jul;8(7):895-911. DOI:10.1158/2326-6066.CIR-19-0321
Bapotulimab Preparation Products And Raw materials
Raw materials
Preparation Products
Bapotulimab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
| Wanxin Biotechnology (Jiaxing) Co., LTD | 0573-83568680 18057391398 | 3956524501@qq.com | China | 1441 | 58 |
| Atagenix Laboratories | 027-87008169 17762441161 | info@atagenix.com | China | 9997 | 58 |
| Wuhan Maixi Biotechnology Co., Ltd | 18007167883 18007167883 | Service@mabnus.com | China | 921 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
