Lusvertikimab
- CAS No.
- 2375835-91-7
- Chemical Name:
- Lusvertikimab
- Synonyms
- Lusvertikimab;Lusvertikimab (anti-CD127);Research Grade Lusvertikimab;Research Grade Lusvertikimab (DHD19401)
- CBNumber:
- CB010617047
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | H1V41MWX63 |
Lusvertikimab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 591987 | Lusvertikimab ≥95% | 2375835-91-7 | 100ug | $829 | 2026-06-03 | Buy |
| ChemScene | CS-0624134 | Lusvertikimab 99.41% | 2375835-91-7 | 1mg | $303 | 2026-06-04 | Buy |
| ChemScene | CS-0624134 | Lusvertikimab 99.41% | 2375835-91-7 | 5mg | $737 | 2026-06-04 | Buy |
| ChemScene | CS-0624134 | Lusvertikimab 99.41% | 2375835-91-7 | 10mg | $1137 | 2026-06-04 | Buy |
| aablocks | AA02A2PJ | Lusvertikimab ≥95%(SDS-PAGE&SEC-HPLC) | 2375835-91-7 | 1mg | $532 | 2026-06-02 | Buy |
Lusvertikimab Chemical Properties, Uses, Production
Uses
Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research[1].
in vivo
OSE-127 treated mice shows a reduction of peripheral blood (PB) blasts in 21/22 (95%) PDX samples in vivo when the corresponding control mice showed clinical signs of overt leukemia[1].
IC 50
IL7R
References
[1] Lennart Lenk, et al. The IL7R-Antagonist OSE-127 Blocks Acute Lymphoblastic Leukemia Development Via a Dual Mode of Action. ACUTE LYMPHOBLASTIC LEUKEMIAS: BIOMARKERS, MOLECULAR MARKERS AND MINIMAL RESIDUAL DISEASE IN DIAGNOSIS AND PROGNOSIS| NOVEMBER 15, 2022.
[2] Elodie Rivière,, et al. Interleukin-7/Interferon Axis Drives T Cell and Salivary Gland Epithelial Cell Interactions in Sjgren's Syndrome. Arthritis Rheumatol. 2021 Apr;73(4):631-640. DOI:10.1002/art.41558
Lusvertikimab Preparation Products And Raw materials
Raw materials
Preparation Products
Lusvertikimab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
View Latest Price from Lusvertikimab manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Lusvertikimab
2375835-91-7
|
$228.00-868.00 | 95.00% | 10g | TargetMol Chemicals Inc. |
-
- Lusvertikimab
2375835-91-7
- $228.00-868.00
- 95.00%
- TargetMol Chemicals Inc.
