ChemicalBook >> CAS DataBase List >>Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2)

Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2)

Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2) structure

CAS No.: 1781932-33-9

Chemical Name:: Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2)

Synonyms: Compound T5398(SC);Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2)

CBNumber:: CB010714166

Molecular Formula:: C27H28ClFN8O3

Molecular Weight:: 567.02

MDL Number:

MOL File:: 1781932-33-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:22:16

Request For Quotation

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P305+P351+P338

Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA01LQRW	BMS-599626 2HCL(714971-09-2 Free base)	1781932-33-9	1mg	$60	2026-05-30	Buy
aablocks	AA01LQRW	BMS-599626 2HCL(714971-09-2 Free base)	1781932-33-9	5mg	$111	2026-05-30	Buy
aablocks	AA01LQRW	BMS-599626 2HCL(714971-09-2 Free base)	1781932-33-9	10mg	$163	2026-05-30	Buy
aablocks	AA01LQRW	BMS-599626 2HCL(714971-09-2 Free base)	1781932-33-9	25mg	$322	2026-05-30	Buy
aablocks	AA01LQRW	BMS-599626 2HCL(714971-09-2 Free base)	1781932-33-9	50mg	$467	2026-05-30	Buy

Product number	Packaging	Price	Buy
AA01LQRW	1mg	$60	Buy
AA01LQRW	5mg	$111	Buy
AA01LQRW	10mg	$163	Buy
AA01LQRW	25mg	$322	Buy
AA01LQRW	50mg	$467	Buy

Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2) Chemical Properties, Uses, Production

Uses

BMS-599626 dihydrochloride is a small molecule pan-HER (human epidermal growth factor receptor) kinase inhibitor. BMS-599626 dihydrochloride primarily targets HER1 (IC50=20 nmol/L) and HER2 (IC50=30 nmol/L) kinase activity in the HER family. BMS-599626 inhibits the kinase activity of HER1 and HER2 by competing with their ATP-binding sites, and can inhibit the downstream signaling pathway by blocking the heterodimer formation of HER1 and HER2. BMS-599626 dihydrochloride can be used to study the antitumor effects of multiple HER1 or HER2 overexpressed tumor models[1].

IC 50

HER1: 20 nM (IC₅₀); HER2: 30 nM (IC₅₀)

References

[1] Wong T W, et al. Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling[J]. Clinical cancer research, 2006, 12(20): 6186-6193. DOI:10.1158/1078-0432.CCR-06-0642

Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2) Preparation Products And Raw materials

Raw materials

Preparation Products

Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2) Suppliers

Global Suppliers ( 10)

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	5985	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11963	58
Shanghai Amole Biotechnology Co., Ltd.	13370042665 18916960931	2596183085@qq.com	China	17234	58
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58
Aladdin Scientific		tp@aladdinsci.com	United States	50089	58

Supplier	Advantage
BOC Sciences	58
TargetMol Chemicals Inc.	58
Nantong QuanYi Biotechnology Co., Ltd	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Shanghai Amole Biotechnology Co., Ltd.	58
TargetMol	58
Aladdin Scientific	58

Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2) Spectrum

Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2)(1781932-33-9)¹HNMR

1781932-33-9 (Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2)) Related Search:

EGFR Protein, HUMAN (621A.A, HEK293, FC) EGFR protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) HER2/CD340 protein, HUMAN (BIOTINYLATED, HEK293, HIS) HER3 Protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) AZD-9291

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Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, hydrochloride (1:2) Compound T5398(SC) 1781932-33-9