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ChemicalBook >> CAS DataBase List >>3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole Structure
3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole structure
CAS No.
936250-20-3
Chemical Name:
3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
Synonyms
5-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;5-Methylpyrazole-4-boronic acid, pinacol ester;5-Methylpyr;3-Methyl-4-(4;3-Methyl-4-pyrazole boronic acid pinacol ester;3-Methyl-1H-pyrazole-4-boronic acid pinacol ester;3-Methyl-1H-pyrazole-4-boronicacid,pinacolester96%;(3-METHYL-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER;3-Methyl-1H-pyrazole-4-boronic acid pinacol ester 97%;5-Methyl-1H-pyrazole-4-boronic acid, pinacol ester 96%
CBNumber:
CB01113235
Molecular Formula:
C10H17BN2O2
Molecular Weight:
208.07
MDL Number:
MFCD08690235
MOL File:
936250-20-3.mol
MSDS File:
SDS
Last updated:2026-05-27 17:22:33
Request For Quotation

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole Properties

Melting point 129-134℃
Boiling point 350.3±30.0 °C(Predicted)
Density 1.07±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
pka 13.92±0.50(Predicted)
color White
InChI InChI=1S/C10H17BN2O2/c1-7-8(6-12-13-7)11-14-9(2,3)10(4,5)15-11/h6H,1-5H3,(H,12,13)
InChIKey MSJAEFFWTBMIKT-UHFFFAOYSA-N
SMILES N1C=C(B2OC(C)(C)C(C)(C)O2)C(C)=N1
CAS DataBase Reference 936250-20-3
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HS Code  29349990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 706078 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester 97% 936250-20-3 250mg $153 2026-04-30 Buy
Sigma-Aldrich 706078 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester 97% 936250-20-3 1g $349 2026-04-30 Buy
Usbiological 283459 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester Asreported 936250-20-3 250mg $442 2026-06-03 Buy
Usbiological 283459 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester Asreported 936250-20-3 500mg $631 2026-06-03 Buy
Usbiological 283459 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester Asreported 936250-20-3 1g $887 2026-06-03 Buy
Product number Packaging Price Buy
706078 250mg $153 Buy
706078 1g $349 Buy
283459 250mg $442 Buy
283459 500mg $631 Buy
283459 1g $887 Buy

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole Chemical Properties, Uses, Production

Chemical Properties

Solid

Uses

suzuki reaction

Synthesis

tert-Butyl 4-bromo-3-methyl-1H-pyrazole-1-carboxylate

1021919-24-3

Bis(pinacolato)diboron

73183-34-3

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

936250-20-3

The general procedure for the synthesis of 3-methylpyrazole-4-boronic acid pinacol ester from 4-bromo-3-methyl-1H-pyrazole-1-carboxylic acid tert-butyl ester and pinacol ester of bis-boronic acid is as follows: 1. tert-butyl 4-bromo-3-methyl-1H-pyrazole-1-carboxylate (0.48 g, 1.84 mmol), bis(pinacolato)diboron (0.535 g, 2.1 mmol), dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct (0.156 g, 0.19 mmol), and potassium acetate ( 0.56 g, 5.7 mmol) were added sequentially to a sealed tube. 2. Add DMSO (5 mL) as a solvent to ensure that all solids are fully dissolved. 3. Flush the reaction system with nitrogen to remove oxygen and subsequently seal the reaction tube. 4. Heat the reaction mixture to 90°C and maintain this temperature for 18 hours. 5. 5. Upon completion of the reaction, the solvent was removed and the crude product was purified by silica gel column chromatography (eluent: 50% ethyl acetate in hexane solution) to afford the target compound, 3-methylpyrazole-4-boronic acid pinacol ester (0.2 g, 50% yield). 6. The structure of the product was confirmed by mass spectrometry (ESI), m/z 209.1 [M + 1]+.

References

[1] Patent: WO2008/51493, 2008, A2. Location in patent: Page/Page column 181
[2] Patent: US2013/123281, 2013, A1. Location in patent: Paragraph 0127

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole Preparation Products And Raw materials

Raw materials

tert-Butyl 4-bromo-3-methyl-1H-pyrazole-1-carboxylate Bis(pinacolato)diboron Potassium Acetate Dimethyl sulfoxide

Preparation Products

1,5-Dimethyl-1H-pyrazole-4-boronic acid,pinacol ester

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole Suppliers

Global Suppliers ( 147)
Supplier Tel Email Country ProdList Advantage
Shanghai Youmede Technology Co., LTD 18964944463 56810034@qq.com China 40 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Shanghai Chem-Milestone Co., Ltd 021-50273253 13641951838 chemmilestone@163.com China 149 62
Supplier Advantage
Shanghai Youmede Technology Co., LTD 58
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Pure Chemistry Scientific Inc. 62
Adamas Reagent, Ltd. 59
Accela ChemBio Co.,Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Syntechem Co.,Ltd 57
Shanghai Chem-Milestone Co., Ltd 62

View Latest Price from 3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Methyl-1H-pyrazole-4-boronic acid pinacol ester pictures 2026-08-25 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester
936250-20-3
 $3.00-9.00 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole pictures 2021-07-13 3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
936250-20-3
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole pictures 2021-07-10 3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
936250-20-3
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole Spectrum

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole(936250-20-3)1HNMR

936250-20-3 (3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole) Related Search:

Boric acid 5-Amino-3-methylpyrazole-4-boronic acid pinacol ester 1-(2,2-Dimethoxy-ethyl)-3,5-dimethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole 5-Methyl-1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1-tert-Butoxycarbonyl-3,5-dimethylpyrazole-4-boronic acid, pinacol ester
1,3,5-Trimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1,5-Dimethyl-1H-pyrazole-4-boronic acid,pinacol ester 1,3-Dimethyl-1H-pyrazole-4-boronic acid,pinacol ester 3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

1of2

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole (3-METHYL-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER 5-Methylpyr 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester 5-Methyl-1H-pyrazole-4-boronic acid, pinacol ester 96% 5-Methylpyrazole-4-boronic acid, pinacol ester 1H-Pyrazole, 3-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- 3-Methyl-4-pyrazole boronic acid pinacol ester 3-Methyl-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-methyl-1H-pyrazol-4-yl)boronate 3-Methyl-1H-pyrazole-4-boronicacid,pinacolester96% 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester 97% 3-Methyl-4-(4 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-... 936250-20-3 3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole 3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester 2-?Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole 3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole - [M10036] 5-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 936250-20-3