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Methanol-d4

Methanol-d4 Structure
Methanol-d4 structure
CAS No.
811-98-3
Chemical Name:
Methanol-d4
Synonyms
CD3OD;Deuterated methanol;Methanol-d4, 99.5 atom % D, for NMR;METHYL-D3 ALCOHOL-D;99.96 atom % D, 99% (CP);trideuterio(deuteriooxy)methane;METHANOL-D4;METHANOL-4D;D4-Methanol;% (v/v) TMS
CBNumber:
CB0111579
Molecular Formula:
CD4O
Molecular Weight:
36.07
MDL Number:
MFCD00044637
MOL File:
811-98-3.mol
MSDS File:
SDS
Last updated:2026-08-28 09:17:35
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Methanol-d4 Properties

Melting point -99 °C
Melting point -97,8°C
Boiling point 64,7°C
Boiling point 65.4 °C(lit.)
Density 0.888 g/mL at 25 °C(lit.)
Density d = 0,89
vapor pressure 129 hPa (20 °C)
refractive index n20/D 1.326(lit.)
Flash point 52 °F
storage temp. no restrictions.
solubility Chloroform (Slightly), Water (Slightly)
form Liquid
color Colorless
Specific Gravity 0.89
Solvent Residual Peak 1H NMR：3.31 ppm (quint)
13C NMR：49.00±0.01 ppm (sept)
explosive limit 5.5-36.5%(V)
Water Solubility Miscible with water, ethanol, ether, acetone and chloroform.
BRN 1733278
Exposure limits ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)
OSHA: TWA 200 ppm(260 mg/m3)
NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3)
Stability Stable. Incompatible with moisture, acids, acid chlorides, acid anhydrides, oxidizing agents, reducing agents, alkali metals. Highly flammable.
InChI 1S/CH4O/c1-2/h2H,1H3/i1D3,2D
InChIKey OKKJLVBELUTLKV-MZCSYVLQSA-N
SMILES [2H]OC([2H])([2H])[2H]
CAS DataBase Reference 811-98-3(CAS DataBase Reference)
EPA Substance Registry System Methanol-d4 (811-98-3)
UNSPSC Code 12352104
NACRES NA.22
CAS Number Unlabeled 67-56-1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P233-P280-P301+P310-P303+P361+P353-P304+P340+P311
target organs Eyes,Central nervous system
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  7-16-36/37-45
RIDADR  UN 1230 3/PG 2
WGK Germany  1
RTECS  PC1400000
F  10-21
Autoignition Temperature 440 °C
TSCA  TSCA listed
HazardClass  3
PackingGroup  II
HS Code  28459000
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1
Toxicity LD50 orally in Rabbit: 5628 mg/kg LD50 dermal Rabbit 17100 mg/kg
Limited Quantities 1.0 L (0.3 gallon) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
3
1 0

Methanol-d4 price More Price(128)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 444758 Methanol-d4 "100%", 99.96 atom % D 811-98-3 1g $106 2026-04-30 Buy
Sigma-Aldrich 444758 Methanol-d4 "100%", 99.96 atom % D 811-98-3 10g $570 2026-04-30 Buy
Sigma-Aldrich 151947 Methanol-d4 ≥99.8 atom % D 811-98-3 1g $38.1 2026-04-30 Buy
Sigma-Aldrich 151947 Methanol-d4 ≥99.8 atom % D 811-98-3 10g $185 2026-04-30 Buy
Sigma-Aldrich 151947 Methanol-d4 ≥99.8 atom % D 811-98-3 50g $719 2026-04-30 Buy
Product number Packaging Price Buy
444758 1g $106 Buy
444758 10g $570 Buy
151947 1g $38.1 Buy
151947 10g $185 Buy
151947 50g $719 Buy

Methanol-d4 Chemical Properties, Uses, Production

Chemical Properties

colourless liquid

Characteristics

Methanol-d4 has a slightly higher density than methanol because deuterium atoms are heavier than hydrogen atoms. It exhibits distinct characteristics in its nuclear magnetic resonance (NMR) spectrum, with characteristic deuterium signals arising from the nuclear spin of deuterium.

Uses

Methanol-d4 may be used as a solvent to analyze the rate of exchange of methoxyl group in camphor and norcamphor dimethyl ketals.

Application

Methyl Alcohol-d4 is the labeled analog of methyl alcohol, a common laboratory solvent used primarily in spectroscopic techniques (UV/VIS, NMR, IR).

Definition

ChEBI: Methanol-d4 is a deuterated compound that is methanol in which all four hydrogen atoms are replaced by deuterium. It is commonly used as a solvent in NMR spectroscopy. It has a role as an amphiprotic solvent.

General Description

Methanol-d4 (CD3OD) is a deuterated NMR solvent used for NMR-based research and analyses. It has the highest isotopic enrichment and will not interfere with the desired level of detection.
The absolute infrared absorption intensities of CD3OD have been reported between 8000 and 350cm-1.

Synthesis

A preparation method for providing per-deuterated methanol is provided, specifically: opening the valve of deuterium gas and carbon monoxide, and controlling the volume ratio to be 1:1 to carry out premixing (deuterium gas and carbon monoxide are respectively 2kg and 14kg, a total of 16kg). Under the pressure of 5.5MPa, at a speed of 2L/s, through the catalyst bed layer of gold oxide: platinum oxide: rhodium oxide = 1:3:2 (mass ratio) at 210~380℃, after continuous circulation reaction for 24 hours, in The per-deuterated methanol reaction solution was obtained from the separation kettle, and the obtained reaction solution was rectified to give Methanol-d4: 3.2 kg, yield 35.5%, purity 99.8%.

Methanol-d4 Preparation Products And Raw materials

Raw materials

Preparation Products

Tetrahydrofuran-d8 Ethanol-d 4-Methylbenzyl acetate KISVAASFGZJBCY-BMSJAHLVSA-N Methyl Salicylate-d3
3-Methyl-d3-indole

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Methanol-d4 Suppliers

Global Suppliers ( 284)
Supplier Tel Email Country ProdList Advantage
China Langchem Inc. 021-58956006,021-58950017 15800617331 sales@langchem.com China 209 57
CHINA ISOTOPE CO., LIMITED 02151600108 13062666369 info@isotopechem.com China 4721 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan eastop Technology Co., ltd.6 18086015167 17702779303 service@isotopechina.com China 268 58
Ningbo cuiying chemical technology co. LTD 0574-88162057 18957423231 2317559463@qq.com China 323 58
Shanghai Chemisci Technology Co., Ltd 021-58690851 15690882017 1877080091@qq.com China 7514 58
Shanghai wechem chemical co., ltd 18824865657 2684615189@qq.com China 428 58
Anhui Weihe Chemical Technology Co., Ltd. 13505592528 13505592528 49141484@qq.com China 2671 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Supplier Advantage
China Langchem Inc. 57
CHINA ISOTOPE CO., LIMITED 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Energy Chemical 61
Wuhan eastop Technology Co., ltd.6 58
Ningbo cuiying chemical technology co. LTD 58
Shanghai Chemisci Technology Co., Ltd 58
Shanghai wechem chemical co., ltd 58
Anhui Weihe Chemical Technology Co., Ltd. 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58

View Latest Price from Methanol-d4 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methanol-D4 pictures 2026-09-18 Methanol-D4
811-98-3
 $54.00-606.00 5g 0.99 25kg Shanghai UCHEM Inc.
Methanol-d4 pictures 2026-09-02 Methanol-d4
811-98-3
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
Methanol-d4 pictures 2026-06-30 Methanol-d4
811-98-3
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
  • Methanol-D4 pictures
  • Methanol-D4
    811-98-3
  • $54.00-606.00
  • 0.99
  • Shanghai UCHEM Inc.
  • Methanol-d4 pictures
  • Methanol-d4
    811-98-3
  • $1.00-100.00
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • Methanol-d4 pictures
  • Methanol-d4
    811-98-3
  • $0.00
  • 99%
  • Shaanxi Dideu New Materials Co. Ltd

Methanol-d4 Spectrum

Methanol-d4(811-98-3)MSMethanol-d4(811-98-3)1HNMRMethanol-d4(811-98-3)13CNMRMethanol-d4(811-98-3)IR1Methanol-d4(811-98-3)Raman

811-98-3 (Methanol-d4) Related Search:

1-AMINOCYCLOPROPYL-METHANOL 1,1,1-DIPHENYL-(N-METHYL-PYRROLINE-2YL)-METHANOL (1,5-Dimethyl-1H-pyrazol-3-yl)methanol (1,4-Dimethyl-2-piperazinyl)methanol Methanol-d4
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Methanol-d4, 99.6+ atom % D, for NMR Methanol-d4, 99.8 atom % D, for NMR Methanol-d4, contains 0.03% V/V % TMS, 99.8 atom % D, for NMR Methanol-d4, packaged in 0.50 ml ampules, 100.0 atom % D, for NMR Methanol-d4, packaged in 0.75 ml ampules, 100.0 atom % D, for NMR Methanol-d4 99 atom % D Methanol-d4 99.8 atom % D, contains 0.05 % (v/v) TMS (2H4)methanol METHANOL-D4, 100.0 ATOM % D (1PK=10 X 0.25ML) METHANOL-D4 , 99.8 + ATOM % D (1PK=5 X 0.5ML) METHYL-D3 ALCOHOL-D, 99.8+ ATOM % D (CON TAINS 1% V/V TMS) Methanol-D4 METHANOL-D4, 99.8 + ATOM % D (1PK=10 X 1ML) METHYL-D3 ALCOHOL-D, 100.0 ATOM % D METHYL-D3 ALCOHOL-D, 99.8+ATOM % D (SEPTUM VIALS) METHYL-D3 ALCOHOL-D, 99.8+ ATOM % D (CON TAINS 0.03% V/V TMS) METHYL-12C-D3 ALCOHOL-D, 99.95 ATOM % 12 C, 99.5 ATOM % D METHYL ALCOHOL-D4+0.05% TMS (V/V) (~0.7 METHYL-D3 ALCOHOL-D, 99.8 ATOM % D, ANH& METHANOL-D4, 99.8 ATOM % D METHYL-D3 ALCOHOL-D, 99+ ATOM % D METHYL-D3 ALCOHOL-D, 99.95 ATOM % D (1PK =10 X 0.5ML) METHYL-D3 ALCOHOL-D, 99.8 ATOM % D (CONT METHYL-D3 ALCOHOL-D, 100 ATOM % D(CONTAINS 0.03% V/V TMS) METHANOL-D(4) VIAL WITH 10 ML >99.95 ( METHYL-D3 ALCOHOL-D, 99.8+ ATOM % D, AN& METHANOL-D4, 99.8 + ATOM % D (1PK=10 X 0.75ML) METHYL-D3 ALCOHOL-D, 99.8+ ATOM % D (CON TAINS 0.1% V/V TMS) METHYL-D3 ALCOHOL-D, 99.8 + ATOM % D (0.0 3% V/V TMS, 1PK=10 X 1ML) Methanol-d4, isotopic purity 99.5+% Methanol-d4,99.8%(Isotopic) Methanol-d4,99.8%(Isotopic),contains0.05%v/vTMS Methanol-d4, 100.0 atom % D, for NMR Methanol-d4 99.8atom%D (0.75mL*10) ACETIC ANHYDRIDE SOLUTION R1 PHE CALCIUM NITRATE TETRAHYDRATE GRAN HYDROXYDE CUPRIETHYLE SOL. PHE SOLUTION IC MORPHOLINE 1G/L IN H2O Methyl-d3 alcohol-d,99.5 atom Methanol-d4, contains 0.05% TMS, 99.8% Isotopic METHANOL-D4, >=99.8 ATOM % D, CONTAINS & MethanolD4>99.8%(+0.03%tms) MethanolD4>99.8%10x0.75ml MethanolD4>99.96%10x0.75ml MethanolD4>99.8%10X0.6ml Tetradeuterio-methanol Methanol-D4 "100%" >99.95 Atom % D Methanol-D4 >99.5 Atom % D Methanol-d4, 100%(Isotopic) Methyl-d3 alcohol d, Tetradeuteromethanol (1,1,1,O-2H4)Methanol (O-2H,2H3)Methanol Methanol-d4,for NMR,packaged in 0.50 ml ampules, 100.0 atom % D Methanol-d4,for NMR,contains 0.03 v/v% TMS, 99.8% atom% D Methanol-d4,for NMR,packaged in 0.75 ml ampules, 99.8 atom % D Methanol-d4,packaged in 0.75 ml ampules, 99.95 atom % D Methanol-d4,for NMR,with 0.03% TMS, in 0.75 ml ampules, 99.8 atom % D Methanol-d4,for NMR,99.5 atom % D