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2-Bromo-4-(trifluoro methyl)pryrimidine

2-Bromo-4-(trifluoro methyl)pryrimidine Structure
2-Bromo-4-(trifluoro methyl)pryrimidine structure
CAS No.
785777-87-9
Chemical Name:
2-Bromo-4-(trifluoro methyl)pryrimidine
Synonyms
2-Bromo-4-(trifluoro methyl)pryrimidine;Pyrimidine, 2-bromo-4-(trifluoromethyl)-;2-Bromo-4-(trifluoro methyl)pryrimidine ISO 9001：2015 REACH
CBNumber:
CB01154401
Molecular Formula:
C5H2BrF3N2
Molecular Weight:
226.98
MDL Number:
MFCD09802248
MOL File:
785777-87-9.mol
MSDS File:
SDS
Last updated:2026-05-27 16:58:06
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2-Bromo-4-(trifluoro methyl)pryrimidine Properties

Melting point 21-23 °C
Boiling point 247℃
Density 1.807
refractive index 1.475
Flash point 103℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form low melting solid
pka -4.12±0.20(Predicted)
color Light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P261-P271-P280
HS Code  2933599590

2-Bromo-4-(trifluoro methyl)pryrimidine price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC908649 2-Bromo-4-(trifluoromethyl)pyrimidine 97% 785777-87-9 250mg $28 2026-06-04 Buy
Apolloscientific PC908649 2-Bromo-4-(trifluoromethyl)pyrimidine 97% 785777-87-9 1g $70 2026-06-04 Buy
Apolloscientific PC908649 2-Bromo-4-(trifluoromethyl)pyrimidine 97% 785777-87-9 5g $225 2026-06-04 Buy
Activate Scientific AS22206 2-Bromo-4-(trifluoromethyl)pyrimidine 98% 785777-87-9 1g $94 2026-06-04 Buy
Activate Scientific AS22206 2-Bromo-4-(trifluoromethyl)pyrimidine 98% 785777-87-9 5g $265 2026-06-04 Buy
Product number Packaging Price Buy
PC908649 250mg $28 Buy
PC908649 1g $70 Buy
PC908649 5g $225 Buy
AS22206 1g $94 Buy
AS22206 5g $265 Buy

2-Bromo-4-(trifluoro methyl)pryrimidine Chemical Properties, Uses, Production

Synthesis

2-Hydroxy-4-(trifluoromethyl)pyrimidine

104048-92-2

2-Bromo-4-(trifluoro methyl)pryrimidine

785777-87-9

General procedure for the synthesis of 2-bromo-4-trifluoromethylpyrimidines from 4-(trifluoromethyl)pyrimidin-2(1H)-ones:[0604] Synthesis of 2-bromo-4-(trifluoromethyl)pyrimidines:[0605] To a stirred toluene solution (40 mL) of 6-(trifluoromethyl)-1,2-dihydropyrimidin-2-ol (2 g, 12.19 mmol), protected by argon gas To this solution, phosphorus bromide (5.24 g, 18.20 mmol) and N,N-dimethylaniline (156 mg, 1.20 mmol) were sequentially added at room temperature. The reaction mixture was heated to 100 °C and stirred for 3 hours. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was diluted with 50 mL of water and extracted with hexane (2 x 50 mL). The organic phases were combined, washed with 50 mL of water, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 2-bromo-4-(trifluoromethyl)pyrimidine as a light yellow oil (800 mg, 29% yield). The product was characterized by 1H-NMR (CDCl3, 500MHz): δ 8.82 (d, 1H), 7.64 (d, 1H); TLC conditions: 10% EtOAc/hexane (Rf 0.8).

References

[1] Patent: WO2013/142269, 2013, A1. Location in patent: Paragraph 0604; 0605; 0606

2-Bromo-4-(trifluoro methyl)pryrimidine Preparation Products And Raw materials

Raw materials

2-Hydroxy-4-(trifluoromethyl)pyrimidine N,N-Dimethylaniline Toluene Phosphorus oxybromide

Preparation Products

2-Bromo-4-(trifluoro methyl)pryrimidine Suppliers

Global Suppliers ( 92)
Supplier Tel Email Country ProdList Advantage
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Nan Jing Dirise Chemcial Co.,LTD 025-52161033 15312098939 2432674894@qq.com China 585 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2853 52
Abblis Chemicals LLC +1-832-373-8299 info@abblis.com United States 322 57
Supplier Advantage
Pure Chemistry Scientific Inc. 62
Accela ChemBio Co.,Ltd. 64
Nan Jing Dirise Chemcial Co.,LTD 64
Shandong Xiya Chemical Co., Ltd 57
Shanghai Topbiochem Technology Co., Ltd 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
SynAsst Chemical. 55
Shanghai Witofly Chemical Co.,Ltd 52
Abblis Chemicals LLC 57

View Latest Price from 2-Bromo-4-(trifluoro methyl)pryrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-4-(trifluoro methyl)pryrimidine pictures 2026-08-20 2-Bromo-4-(trifluoro methyl)pryrimidine
785777-87-9
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-Bromo-4-(trifluoro methyl)pryrimidine pictures 2020-02-19 2-Bromo-4-(trifluoro methyl)pryrimidine
785777-87-9
 $7.00 1KG 99% 100kg Career Henan Chemical Co

2-Bromo-4-(trifluoro methyl)pryrimidine Spectrum

2-Bromo-4-(trifluoro methyl)pryrimidine(785777-87-9)1HNMR2-Bromo-4-(trifluoro methyl)pryrimidine(785777-87-9)FT-IR

785777-87-9 (2-Bromo-4-(trifluoro methyl)pryrimidine) Related Search:

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Pyrimidine, 2-bromo-4-chloro-6-(trifluoromethyl)-

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2-Bromo-4-(trifluoro methyl)pryrimidine Pyrimidine, 2-bromo-4-(trifluoromethyl)- 2-Bromo-4-(trifluoro methyl)pryrimidine ISO 9001：2015 REACH 785777-87-9 alkyl bromide Fluorine series