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Cafedrine

Cafedrine Structure
Cafedrine structure
CAS No.
58166-83-9
Chemical Name:
Cafedrine
Synonyms
Cafedrine;Cafedrina;Brn 0583473;l-Cafedrine;(-)-Cafedrine;Cafedrina [inn-spanish];7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline;7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline;7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione
CBNumber:
CB01178203
Molecular Formula:
C18H23N5O3
Molecular Weight:
357.412
MDL Number:
MFCD00865826
MOL File:
58166-83-9.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51
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Cafedrine Properties

Boiling point 591.6±52.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
pka 13.90±0.20(Predicted)
FDA UNII 0UYY5V4U2Q
ATC code C01CA21

Cafedrine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00EIKN (-)-Cafedrine 58166-83-9 1mg $255 2026-05-28 Buy
aablocks AA00EIKN (-)-Cafedrine 58166-83-9 5mg $598 2026-05-28 Buy
aablocks AA00EIKN (-)-Cafedrine 58166-83-9 10mg $810 2026-05-28 Buy
aablocks AA00EIKN (-)-Cafedrine 58166-83-9 25mg $1236 2026-05-28 Buy
aablocks AA00EIKN (-)-Cafedrine 58166-83-9 50mg $1604 2026-05-28 Buy
Product number Packaging Price Buy
AA00EIKN 1mg $255 Buy
AA00EIKN 5mg $598 Buy
AA00EIKN 10mg $810 Buy
AA00EIKN 25mg $1236 Buy
AA00EIKN 50mg $1604 Buy

Cafedrine Chemical Properties, Uses, Production

Originator

Praxinor,Merck Lipha Sante

Uses

(-)-Cafedrine is composed of linked Phenylpropanolamine (P336100) and Theophylline (T343850). It is used to regulate and restore blood pressure.

Manufacturing Process

7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of 7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline hydrochloride was filtered off and dried. MP 243°-244°C.
In practice it is usually used as free base.

Therapeutic Function

Analeptic

Cafedrine Preparation Products And Raw materials

Raw materials

Preparation Products

Cafedrine Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
BOC Sciences 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Amole Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from Cafedrine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cafedrine pictures 2026-05-11 Cafedrine
58166-83-9
 $293.00-987.00 99.77% 10g TargetMol Chemicals Inc.
  • Cafedrine pictures
  • Cafedrine
    58166-83-9
  • $293.00-987.00
  • 99.77%
  • TargetMol Chemicals Inc.

Cafedrine Spectrum

Cafedrine(58166-83-9)1HNMR

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Cafedrine Fenethylline 7-(2-aminoethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione

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Cafedrine 3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione 7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione 7-(2-((Alphas,betar)-beta-hydroxy-alpha-methylphenethylamino)ethyl)-1,3-dimethyl-2,6(1H,3H)purindion 7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline 7-(2-{[(1R,2S)-1-Hydroxy-1-phenyl-2-propanyl]amino}ethyl)-1,3-dim ethyl-3,7-dihydro-1H-purine-2,6-dione 7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline Brn 0583473 Cafedrina Cafedrina [inn-spanish] 1H-Purine-2,6-dione, 3,7-dihydro-7-[2-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]ethyl]-1,3-dimethyl- (-)-Cafedrine l-Cafedrine 58166-83-9