2-hydroxypentanedioic acid
- CAS No.
- 13095-47-1
- Chemical Name:
- 2-hydroxypentanedioic acid
- Synonyms
- R-2-HYDROXYGLUTARATE;D-2-hydroxyglutarate;D--Hydroxyglutaric Acid;D-α-Hydroxyglutaric Acid;D-2-Hydroxyglutaric acid;(2R)-hydroxyglutaric acid;(R)-2-Hydroxyglutaric acid;2-hydroxypentanedioic acid;D-2-Hydroxyglutaric acid D4;D-alpha-Hydroxyglutaric acid
- CBNumber:
- CB01235779
- Molecular Formula:
- C5H8O5
- Molecular Weight:
- 148.11
- MDL Number:
- MOL File:
- 13095-47-1.mol
| Boiling point | 394.2±27.0 °C(Predicted) |
|---|---|
| Density | 1.508±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; PBS (pH 7.2): 10 mg/mL |
| pka | 3.67±0.10(Predicted) |
| FDA UNII | R9UK2G8Y79 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
2-hydroxypentanedioic acid price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25895 | D-α-Hydroxyglutaric Acid ≥95% | 13095-47-1 | 10mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 25895 | D-α-Hydroxyglutaric Acid ≥95% | 13095-47-1 | 25mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 25895 | D-α-Hydroxyglutaric Acid | 13095-47-1 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 25895 | D-α-Hydroxyglutaric Acid | 13095-47-1 | 5mg | $100 | 2024-03-01 | Buy |
| AK Scientific | 2654CC | (2R)-2-Hydroxypentanedioicacid | 13095-47-1 | 1mg | $133 | 2021-12-16 | Buy |
2-hydroxypentanedioic acid Chemical Properties,Uses,Production
Uses
2-Hydroxypentanedioic Acid is a mouse metabolite
Definition
ChEBI: (R)-2-hydroxyglutaric acid is the (R)-enantiomer of 2-hydroxyglutaric acid. It has a role as an algal metabolite. It is an enantiomer of a (S)-2-hydroxyglutaric acid.
in vivo
D-α-Hydroxyglutaric acid strongly inhibits glucose utilization, CO2 production and the respiratory chain in rat cerebral cortex and human skeletal muscle, as well as in submitochondrial particles from bovine heart, suggesting an impairment of the aerobic metabolism[5].
D-α-Hydroxyglutaric acid has also been proposed as an endogenous excitotoxic organic acid because it significantly decreased cell viability in neuronal cultures from chick embryo telencephalons and from neonatal rat hippocampus through stimulation of specific NMDA glutamate receptors[5].
D-α-Hydroxyglutaric acid (0.01-1 mM) significantly increases chemiluminescence and thiobarbituric acid-reactive substances (TBA-RS) and decreased total antioxidant reactivity (TAR) values in the cortical supernatants in 30-day-old-rats[5].
IC 50
Microbial Metabolite; Human Endogenous Metabolite
2-hydroxypentanedioic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-hydroxypentanedioic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15178 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 | shenlinxing@macklin.cn | China | 15874 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Aikon International Limited | 025-66113011 13155353615 | qzhang@aikonchem.com | China | 15394 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Jiangsu Shengkang Meixiang Technology Co., Ltd. | 18217475093 | 1615396342@qq.com | China | 4309 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29770 | 58 |
| Shijizhuang Zhoukun Pharmaceutical Technology Co., LTD | 0311-83784138 18633934202 | zhoukunpharma@163.com | China | 2026 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62320 | 58 |
