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1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]-

1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]- structure

CAS No.: 1505579-77-0

Chemical Name:: 1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]-

Synonyms: ALKBH5-IN-3;ALKBH5 inhibitor 2;ALKBH5 inhibitor 2 (Cpd 20m);5-Hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylic acid;1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]-

CBNumber:: CB012561920

Molecular Formula:: C11H7F3N2O3

Molecular Weight:: 272.18

MDL Number:

MOL File:: 1505579-77-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:50

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1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]- Properties

Boiling point	447.7±45.0 °C(Predicted)
Density	1.56±0.1 g/cm3(Predicted)
form	Solid
pka	3.71±0.10(Predicted)
color	White to off-white

1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-1234547	ALKBH5-IN-3 99.63%	1505579-77-0	5mg	$54	2026-06-04	Buy
ChemScene	CS-1234547	ALKBH5-IN-3 99.63%	1505579-77-0	10mg	$87	2026-06-04	Buy
ChemScene	CS-1234547	ALKBH5-IN-3 99.63%	1505579-77-0	25mg	$173	2026-06-04	Buy
ChemScene	CS-1234547	ALKBH5-IN-3 99.63%	1505579-77-0	50mg	$282	2026-06-04	Buy
aablocks	AA02ALVL	5-Hydroxy-1-(3-(Trifluoromethyl)Phenyl)-1H-Pyrazole-3-Carboxylic Acid >98%	1505579-77-0	5mg	$91	2026-06-02	Buy

Product number	Packaging	Price	Buy
CS-1234547	5mg	$54	Buy
CS-1234547	10mg	$87	Buy
CS-1234547	25mg	$173	Buy
CS-1234547	50mg	$282	Buy
AA02ALVL	5mg	$91	Buy

1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]- Chemical Properties, Uses, Production

Uses

ALKBH5-IN-3 (Compound 20m) is a potent and selective ALKBH5 inhibitor, with an IC50 of 21 nM. ALKBH5-IN-3 could efficiently stabilize ALKBH5 in HepG2 cells and increase m6A level in intact cells[1].

References

[1] Fang Z, et, al. Discovery of a potent, selective and cell active inhibitor of m6A demethylase ALKBH5. Eur J Med Chem. 2022 Aug 5:238:114446. DOI:10.1016/j.ejmech.2022.114446

1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]- Suppliers

Global Suppliers ( 12)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2994	55
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9729	58
Changzhou Chenhong Biotechnology Co., Ltd.	+86-0519-85788828 +86-13775037613	sales@chemrenpharm.com	China	4058	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	psaitong@jm-bio.com	China	27626	58
InvivoChem	13549236410	sales@invivochem.cn	China	6745	58
Shanghai Haozhu Pharmaceutical Technology Co. , Ltd.	18912729622	66161984@qq.com	China	962	58
SuZhou GoodChemTech Co., Ltd	18136139868; 18136139868	jinlun@goodchemtech.cn	China	321	58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.	025-66061636 19370895928	qqyang@aikonchem.com	China	9995	58
Shaoguan Qicheng Biotechnology Co., Ltd	18122215013	780229652@qq.com	China	1392	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Shanghai Beckham Medical Technology Co., Ltd	55
Shanghai Chaolan Chemical Technology Center	58
Changzhou Chenhong Biotechnology Co., Ltd.	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
InvivoChem	58
Shanghai Haozhu Pharmaceutical Technology Co. , Ltd.	58
SuZhou GoodChemTech Co., Ltd	58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.	58
Shaoguan Qicheng Biotechnology Co., Ltd	58

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1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-[3-(trifluoromethyl)phenyl]- ALKBH5 inhibitor 2 (Cpd 20m) ALKBH5 inhibitor 2 ALKBH5-IN-3 5-Hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylic acid 1505579-77-0