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1H-Indole-3-carboxamide(9CI)

1H-Indole-3-carboxamide(9CI) Structure
1H-Indole-3-carboxamide(9CI) structure
CAS No.
1670-85-5
Chemical Name:
1H-Indole-3-carboxamide(9CI)
Synonyms
1H-Indole-3-carboxamide(9CI);indole-3-yl carboxylic acid amide;2,6-Piperidinedione,3-[(6-chlorophenyl)methyl]-
CBNumber:
CB01282935
Molecular Formula:
C9H8N2O
Molecular Weight:
160.17
MDL Number:
MOL File:
1670-85-5.mol
MSDS File:
SDS
Last updated:2026-05-27 17:17:24
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1H-Indole-3-carboxamide(9CI) Properties

Melting point 201 °C
Boiling point 457.6±18.0 °C(Predicted)
Density 1.328±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 15.80±0.30(Predicted)
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
HS Code  2933998090

1H-Indole-3-carboxamide(9CI) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 280667 1H-Indole-3-carboxylic acid amide Asreported 1670-85-5 1g $581 2026-06-03 Buy
Usbiological 280667 1H-Indole-3-carboxylic acid amide Asreported 1670-85-5 2g $772 2026-06-03 Buy
Usbiological 280667 1H-Indole-3-carboxylic acid amide Asreported 1670-85-5 5g $1027 2026-06-03 Buy
Usbiological 280667 1H-Indole-3-carboxylic acid amide Asreported 1670-85-5 10g $1310 2026-06-03 Buy
Usbiological 280667 1H-Indole-3-carboxylic acid amide Asreported 1670-85-5 25g $1699 2026-06-03 Buy
Product number Packaging Price Buy
280667 1g $581 Buy
280667 2g $772 Buy
280667 5g $1027 Buy
280667 10g $1310 Buy
280667 25g $1699 Buy

1H-Indole-3-carboxamide(9CI) Chemical Properties,Uses,Production

Synthesis

3-Cyanoindole

5457-28-3

1H-Indole-3-carboxamide(9CI)

1670-85-5

GENERAL METHOD: To an anhydrous ethanol solution of 3-cyanoindole (15 mmol) was added 40% aqueous NaOH (5 mL) under stirring conditions. The reaction process was monitored by thin layer chromatography (TLC). Subsequently, 30% aqueous H2O2 solution (10.5 mL, 104.7 mmol) was slowly added dropwise to the reaction mixture. Upon completion of the reaction, the precipitated solid was collected by filtration, washed with water and recrystallized with anhydrous ethanol. Finally, the product was dried under vacuum to give 1H-indole-3-carboxamide (20a). The product was a white solid in 75% yield with a melting point of 195-197 °C (literature value 197-199 °C [31]).1H NMR (δ, ppm): 6.84 (s, 1H, NH), 7.13-7.21 (m, 2H, ArH), 7.47 (d, J = 8.0 Hz, 2H, ArH), 8.08 (s, 1H, NH), 8.20 (d, J = 7.5 Hz, 1H, ArH), 11.60 (s, 1H, NH).

References

[1] Applied Organometallic Chemistry, 2014, vol. 28, # 12, p. 900 - 907
[2] Catalysis Science and Technology, 2015, vol. 5, # 3, p. 1606 - 1622
[3] Synthetic Communications, 2013, vol. 43, # 21, p. 2867 - 2875
[4] Dalton Transactions, 2016, vol. 45, # 34, p. 13590 - 13603
[5] Russian Journal of General Chemistry, 2017, vol. 87, # 12, p. 3006 - 3016

1H-Indole-3-carboxamide(9CI) Preparation Products And Raw materials

Raw materials

3-Cyanoindole Sodium hydroxide Hydrogen peroxide Ethanol

Preparation Products

1H-Indole-3-carboxamide(9CI) Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
DebyeTec.com Inc. 18086626237 18086626237 2693528373@qq.com China 2936 56
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9170 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Shanghai Sealing Biotechnology Co. Ltd.. 15721176654;15710104046 1815535157@qq.com China 984 58
Alfa Chemistry +1-5166625404; Info@alfa-chemistry.com United States 20000 58
Supplier Advantage
Chembest Research Laboratories Limited 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai Raise Chemical Technology Co.,Ltd 55
DebyeTec.com Inc. 56
Alfa Chemistry 60
Amadis Chemical Company Limited 58
Aikon International Limited 58
Shanghai Sealing Biotechnology Co. Ltd.. 58
Alfa Chemistry 58

1H-Indole-3-carboxamide(9CI) Spectrum

1H-Indole-3-carboxamide(9CI)(1670-85-5)1HNMR

1670-85-5(1H-Indole-3-carboxamide(9CI))Related Search:

1-methylindole-3-carboxylic acid methyl ester Piboserod,2H-(1,3)oxazino(3,2-a)indole-10-carboxamide, N-((1-butyl-4-piperidinyl)methyl)-3,4-dihydro- Alosetron Lurosetron 1H-Indole-3-carboxylic acid hydrazide
1H-Indole-3-carboxamide(9CI) FK 888 5,11-dihydro-6H-indolo[3,2-c]quinolin-6-one 3-Carbamoyl-2-methylindole N-(2,6-Dimethylphenyl)-1H-indole-3-carboxamide
N-(4-Chlorophenyl)-1-methyl-2-[(4-methylphenyl)sulfanyl]-1H-indole-3-carboxamide 2-Chloro-1-methyl-N-(4-methylphenyl)-1H-indole-3-carboxamide 2-Chloro-N-(4-chlorophenyl)-1-methyl-1H-indole-3-carboxamide 2-(1H-indole-3-amido)benzoic acid AURORA KA-5158
1H-Indol-3-yl(morpholino)methanone N-(4-Chlorophenyl)-2-[(3-methoxyphenyl)sulfanyl]-1-methyl-1H-indole-3-carboxamide N-(4-Chlorophenyl)-2-[(2,4-dichlorophenyl)sulfanyl]-1-methyl-1H-indole-3-carboxamide

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1H-Indole-3-carboxamide(9CI) indole-3-yl carboxylic acid amide 2,6-Piperidinedione,3-[(6-chlorophenyl)methyl]- 1670-85-5 AMIDE