Prunetin
- CAS No.
- 552-59-0
- Chemical Name:
- Prunetin
- Synonyms
- Cerasin;4',5-DIHYDROXY-7-METHOXYISOFLAVONE;5-Hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one;PRUNETIN;Prunusetin;PRUNETIN(RG);PadMakastein;Prunetin >=98.0% (TLC);Prunetin, 10 mM in DMSO;PRUNASIN(RG)(PLEASE CALL)
- CBNumber:
- CB0131757
- Molecular Formula:
- C16H12O5
- Molecular Weight:
- 284.26
- MDL Number:
- MFCD00016951
- MOL File:
- 552-59-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 240-242°C |
|---|---|
| Boiling point | 346.76°C (rough estimate) |
| Density | 1.2160 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 6.35±0.20(Predicted) |
| color | White to off-white |
| BRN | 292155 |
| InChI | InChI=1S/C16H12O5/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3 |
| InChIKey | KQMVAGISDHMXJJ-UHFFFAOYSA-N |
| SMILES | C1OC2=CC(OC)=CC(O)=C2C(=O)C=1C1=CC=C(O)C=C1 |
| LogP | 3.530 (est) |
| CAS DataBase Reference | 552-59-0(CAS DataBase Reference) |
| FDA UNII | 1TG4H5H11J |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | DJ3100050 |
| F | 10 |
| Storage Class | 11 - Combustible Solids |
Prunetin price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 82415 | Prunetin ≥98.0% (TLC) | 552-59-0 | 5mg | $136 | 2026-04-30 | Buy |
| Sigma-Aldrich | 82415 | Prunetin ≥98.0% (TLC) | 552-59-0 | 25mg | $513 | 2026-04-30 | Buy |
| TCI Chemical | P3232 | Prunetin | 552-59-0 | 50MG | $143 | 2026-04-30 | Buy |
| Cayman Chemical | 29432 | Prunetin ≥95% | 552-59-0 | 5mg | $95 | 2026-04-30 | Buy |
| Cayman Chemical | 29432 | Prunetin ≥95% | 552-59-0 | 10mg | $178 | 2026-04-30 | Buy |
Prunetin Chemical Properties, Uses, Production
Chemical Properties
Yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Rosaceae plant Prunus verecunda Koehne stem Puddun plum P. puddun skin Ziwei family plant wood butterfly Oroxylum indicum Vent. heartwood Leguminosae plant light licorice Glycyrrhiza glabra L.
Uses
Prunetin is isoflavone with diverse biological activities. Prunetin is an antagonist of the progesterone receptor when used at concentrations of 25 and 50 μM.
Definition
ChEBI: A hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group.
Biological Activity
Inhibitor of both cytoplasmic and mitochondrial human liver aldehyde dehydrogenases, possibly by binding at an allosteric site.
Enzyme inhibitor
This Prunus species isoflavone (FW = 284.27 g/mol; CAS 552-59-0; melting point = 240°C), also known as 4’,5-dihydroxy-7- methoxyisoflavone and 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-1- benzopyran-4-one, inhibits alcohol dehydrogenase, aldehyde dehydrogenase, 3’,5’-cyclic-nucleotide phosphodiesterase, phosphodiesterase 4, and protein-tyrosine kinase. Its 4’-glucoside is prunitrin. Methylated isoflavones, such as prunetin, are rapidly converted by CYP1A2 to more active genistein and daidzein, which inhibit.formation of acetaminophen from phenacetin with an IC50 value of 16 μM.
Prunetin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lianyungang Kangcheng Bio Technology Co. | 18151258299 | chuchaosen@126.com | China | 54 | 58 |
| RENI Pharmaceutical Technology Co., Ltd | 028-87865381 18108190480 | 3961643053@qq.com | China | 4321 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
View Latest Price from Prunetin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-08 | Prunetin
552-59-0
|
1g | >=98% | 100kg | Hangzhou ICH Biofarm Co., Ltd | ||
 |
2026-07-27 | Prunetin
552-59-0
|
$32.00-118.00 | 98.43% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-08-11 | Prunetin
552-59-0
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
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