ARV-766
- CAS No.
- 2750830-09-0
- Chemical Name:
- ARV-766
- Synonyms
- Luxdegalutamide;ARV776;ARV-766;JSB-462, ARV-766;Luxdegalutamide ARV-766;4-[4-[[1-[4-[[[trans-3-(4-Cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-N-[(3S)-2,6-dioxo-3-piperidinyl]-2-fluorobenzamide
- CBNumber:
- CB013336286
- Molecular Formula:
- C45H54FN7O6
- Molecular Weight:
- 807.95
- MDL Number:
- MOL File:
- 2750830-09-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
ARV-766 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 41985 | ARV-766 ≥98% | 2750830-09-0 | 1mg | $85 | 2026-04-30 | Buy |
| Cayman Chemical | 41985 | ARV-766 ≥98% | 2750830-09-0 | 5mg | $382 | 2026-04-30 | Buy |
| Cayman Chemical | 41985 | ARV-766 ≥98% | 2750830-09-0 | 10mg | $678 | 2026-04-30 | Buy |
| Cayman Chemical | 41985 | ARV-766 ≥98% | 2750830-09-0 | 25mg | $847 | 2026-04-30 | Buy |
| ChemScene | CS-0693933 | Luxdegalutamide 98.99% | 2750830-09-0 | 1mg | $418 | 2026-06-04 | Buy |
ARV-766 Chemical Properties, Uses, Production
Uses
Luxdegalutamide (ARV-766) is an orally active protein hydrolysis targeted chimeric (PROTAC) targeting androgen receptor (AR), which can degrade AR resistance related mutants, including T878/H875/L702 mutants. Luxdegalutamide has anti-tumor activity and can be used in the study of castration resistant prostate cancer[1][2].
in vivo
Luxdegalutamide exhibits anti-tumor activity in mouse LNCaP and VCaP xenograft models[2].
References
[1] Snyder L, et al. In vitro evaluation of PROTAC degrader ARV-766 for cytochrome P450-and transporter-mediated drug-drug interaction[J]. Drug Metabolism and Pharmacokinetics, 2024, 55: 100881.
[2] Snyder L, et al. Abstract ND03: Discovery of ARV-766, an androgen receptor degrading PROTAC for the treatment of men with metastatic castration resistant prostate cancer[J]. Cancer Research, 2023, 83(7_Supplement): ND03-ND03.
ARV-766 Preparation Products And Raw materials
Raw materials
Preparation Products
ARV-766 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Borl Biotechnology Co.,LTD | 13656121842 | luyan0021@163.com | China | 265 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| Hubei Chuchang Chemical Co., Ltd | 18 15623560702 | info@chuchangbiotech.com | China | 190 | 58 |
| ChemFuture PharmaTech (Jiangsu) Ltd | 5108538618 | suger.wang@chemfuture.com | China | 832 | 65 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1197 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai XingMo Biotechnology Co., Ltd. | +86 13524779951; 13524779951 | 2075692521@qq.com | China | 294 | 55 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 |
View Latest Price from ARV-766 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-10 | Luxdegalutamide
2750830-09-0
|
$318.00-768.00 | 99.95% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-03-16 | Luxdegalutamide (ARV-766)
2750830-09-0
|
5mg | 98%+ HPLC HNMR | 20g | Hubei Chuchang Biotech Co., Ltd. |
-
- Luxdegalutamide
2750830-09-0
- $318.00-768.00
- 99.95%
- TargetMol Chemicals Inc.
-
- Luxdegalutamide (ARV-766)
2750830-09-0
- 98%+ HPLC HNMR
- Hubei Chuchang Biotech Co., Ltd.
