ChemicalBook >> CAS DataBase List >>4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)

4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)

4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) structure

CAS No.: 901128-79-8

Chemical Name:: 4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)

Synonyms: CEP-11981 tosylate;4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)

CBNumber:: CB013384232

Molecular Formula:: C28H27N7O.C7H8O3S

Molecular Weight:: 649.76

MDL Number:

MOL File:: 901128-79-8.mol

Last updated:2025-04-17 18:22:24

Request For Quotation

4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Properties

FDA UNII	YK5DTP8NHU

4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Chemical Properties, Uses, Production

Uses

CEP-11981 (tosylate) (ESK981 (tosylate), BOL 303213X (tosylate)) is an orally active tyrosine kinase inhibitor (TKI), which can target TIE2, VEGFR1-3 and FGFR1, and has potential anti-tumor and anti-angiogenic effects[1].

References

[1] Weiguo Jian, et al. The angiopoietin-TIE2 pathway is a potential therapeutic target in urothelial carcinoma. Anticancer Res. 2014 Jul;34(7):3377-82. PMID:24982343

4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

901128-79-8 (4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)) Related Search:

FGFR-1 alpha (iiic) protein, human (biotinylated, HEK293, His-AVI) FGFR-3 beta (iiic) protein, human (biotinylated, HEK293, His-AVI) FGFR-4 Protein, HUMAN (HEK293, HIS) Futibatinib Formononetin

Ferulic Acid

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4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) CEP-11981 tosylate 901128-79-8