4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)

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4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Basic information
Product Name:4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)
Synonyms:4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1);CEP-11981 tosylate
CAS:901128-79-8
MF:C28H27N7O.C7H8O3S
MW:649.76
EINECS:
Product Categories:
Mol File:901128-79-8.mol
4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Structure
4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Chemical Properties
Safety Information
MSDS Information
4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Usage And Synthesis
UsesCEP-11981 (tosylate) (ESK981 (tosylate), BOL 303213X (tosylate)) is an orally active tyrosine kinase inhibitor (TKI), which can target TIE2, VEGFR1-3 and FGFR1, and has potential anti-tumor and anti-angiogenic effects[1].
References[1] Weiguo Jian, et al. The angiopoietin-TIE2 pathway is a potential therapeutic target in urothelial carcinoma. Anticancer Res. 2014 Jul;34(7):3377-82. PMID:24982343
4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) Preparation Products And Raw materials
Tag:4H-Indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)(901128-79-8) Related Product Information
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